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Tribux Bio

Tribux Bio

Ask a doctor about a prescription for Tribux Bio

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Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Tribux Bio

Package Leaflet: Information for the User

Tribux Bio

100 mg, tablets

Trimebutine maleate

Read the leaflet carefully before taking the medicine, as it contains

important information for the patient.
This medicine should always be taken exactly as described in the patient leaflet or as directed by
the doctor or pharmacist.

  • This leaflet should be kept in case it needs to be read again.
  • If advice or additional information is needed, the pharmacist should be consulted.
  • If the patient experiences any side effects, including any possible side effects not listed in the leaflet, they should inform their doctor or pharmacist. See section 4.
  • If there is no improvement or the patient feels worse after 3 days, they should contact their doctor.

Table of Contents of the Leaflet

  • 1. What is Tribux Bio and what is it used for
  • 2. Important information before taking Tribux Bio
  • 3. How to take Tribux Bio
  • 4. Possible side effects
  • 5. How to store Tribux Bio
  • 6. Contents of the pack and other information

1. What is Tribux Bio and what is it used for

Tribux Bio contains 100 mg of trimebutine per tablet. Trimebutine acts directly on the
smooth muscles of the digestive tract and regulates the motility of the digestive tract. It does not
affect the central nervous system.

Indications for the use of Tribux Bio

  • Digestive disorders characterized by: feeling of fullness, bloating, nausea, and abdominal pain.
  • Functional disorders of the digestive system caused by stress (diarrhea, constipation, abdominal pain). Tribux Bio is intended for short-term treatment. If there is no improvement or the patient feels worse after 3 days, they should consult their doctor.

2. Important information before taking Tribux Bio

When not to take Tribux Bio

  • if the patient is allergic to trimebutine or any other component of this medicine (listed in section 6);
  • if the patient is pregnant.

Children and adolescents

Tribux Bio is not recommended for children under 12 years of age.
Before taking Tribux Bio in children and adolescents over 12 years of age, the doctor should be consulted – see section 3, "Use in children and adolescents".

Tribux Bio and other medicines

The doctor or pharmacist should be informed about all medicines the patient is currently taking or has recently taken, as well as any medicines the patient plans to take.
In particular, the following medicines should be mentioned:

  • zotepine (a medicine used to treat schizophrenia),
  • d-tubocurarine (a muscle relaxant used in general anesthesia).
  • cisapride (a medicine used to treat stomach disorders),
  • procainamide (a medicine used to treat heart rhythm disorders),
  • calcium channel blockers (medicines used to treat high blood pressure and heart disease),
  • captopril (a medicine used to treat high blood pressure),
  • reserpine (a medicine used to treat high blood pressure),
  • midazolam (a medicine used to treat sleep disorders).

Tribux Bio with food and drink

Tribux Bio should be taken before meals, with a glass of water.

Pregnancy and breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before taking this medicine.
Pregnancy
Tribux Bio is contraindicated during pregnancy.
Breastfeeding
Tribux Bio may be used by breastfeeding women only if necessary.

Driving and using machines

Tribux Bio, when taken as directed, does not affect the ability to drive or operate machinery and does not impair psychophysical performance.
Tribux Bio contains lactose(a sugar found in milk).
If the patient has previously been diagnosed with intolerance to some sugars, they should consult their doctor before taking this medicine.

3. How to take Tribux Bio

This medicine should always be taken exactly as described in the patient leaflet or as directed by
the doctor or pharmacist. If there are any doubts, the doctor or pharmacist should be consulted.
The medicine should be taken orally.

Dosage

Adults
1 tablet 2 or 3 times a daybefore meals

Use in children and adolescents

Children and adolescents over 12 years of age
The use of Tribux Bio in this age group should be decided by the doctor.
The daily dose should not exceed 6 mg per kilogram of the child's body weight.
Children under 12 years of age
Tribux Bio is not recommended for children under 12 years of age.

Duration of treatment

Tribux Bio should not be taken for more than 3 days without consulting a doctor.

Method of administration

The tablet should be swallowed whole, with a glass of water.

Taking a higher dose of Tribux Bio than recommended

In case of taking a higher dose of the medicine than recommended, the doctor or pharmacist should be consulted immediately.

Missing a dose of Tribux Bio

A double dose should not be taken to make up for a missed dose.
If a dose is missed, the next dose should be taken at the usual time.

Stopping treatment with Tribux Bio

If there are any further doubts about taking this medicine, the doctor or pharmacist should be consulted.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects may occur when taking Tribux Bio:

Frequent (in 1 to 10 out of 100 people):

  • drowsiness, lethargy,
  • feeling of fatigue,
  • apathy,
  • dizziness,
  • headache,
  • feeling of heat or cold,
  • dry mouth,
  • numbness of the mouth,
  • taste disorders,
  • diarrhea,
  • indigestion,
  • abdominal pain,
  • nausea,
  • vomiting,
  • constipation,
  • feeling of thirst.

Uncommon (in 1 to 10 out of 1000 people):

  • rash.

Rare (in 1 to 10 out of 10,000 people):

  • irregular heartbeat,
  • liver function disorders, including increased activity of liver enzymes AlAT and AspAT in the blood.

Very rare (less than 1 in 10,000 people, including single cases):

  • anxiety,
  • hearing loss,
  • hepatitis,
  • skin changes (itching, hives, redness, blisters, nodules, exudate, erythema),
  • urinary retention,
  • menstrual disorders,
  • painful breast enlargement in women,
  • breast enlargement in men (gynecomastia),
  • breast pain.

Reporting side effects

If any side effects occur, including any side effects not listed in the leaflet, the doctor or pharmacist should be informed. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products
Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Aleje Jerozolimskie 181C
02-222 Warsaw
tel.: +48 22 49 21 301
fax: +48 22 49 21 309
e-mail: [email protected]
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help gather more information on the safety of the medicine.

5. How to store Tribux Bio

The medicine should be stored out of sight and reach of children.
Store in the original packaging, at a temperature below 25°C.
Do not use this medicine after the expiry date stated on the carton and blister.
The expiry date refers to the last day of the given month.
Medicines should not be disposed of via wastewater or household waste. The pharmacist should be asked how to dispose of unused medicines. This will help protect the environment.

6. Contents of the pack and other information

What Tribux Bio contains

  • The active substance is 100 mg of trimebutine maleate.
  • The other ingredients are: lactose monohydrate, microcrystalline cellulose, povidone, crospovidone, and magnesium stearate.

What Tribux Bio looks like and what the pack contains

White or almost white tablets, round, biconvex.
The tablets are packaged in PVC/PVDC-Aluminum or PVC/PE/PVDC-Aluminum blisters placed in a cardboard box.
The pack contains 10 tablets.

Marketing authorization holder and manufacturer

Biofarm Sp. z o. o.
ul. Wałbrzyska 13
60-198 Poznań
tel.: +48 61 66 51 500
fax: +48 61 66 51 505
[email protected]

Date of last revision of the leaflet:

Alternatives to Tribux Bio in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Tribux Bio in Ukraine

Dosage form: tablets, 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, tablets 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, tablets 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, tablets 100mg
Active substance: trimebutine
Prescription required

Alternative to Tribux Bio in Spain

Dosage form: TABLET, 135 mg
Active substance: mebeverine
Prescription required

Online doctors for Tribux Bio

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Tribux Bio – subject to medical assessment and local rules.

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Antonio Cayatte

General medicine43 years of experience

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic.

His clinical background includes:

  • assessment of sudden or unclear symptoms
  • ongoing care for chronic conditions
  • follow-up after hospital discharge
  • interpretation of test results
  • medical support while abroad
Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

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Yevgen Yakovenko

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Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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  • Chronic pain lasting more than 3 months.
  • Migraines and recurring headaches.
  • Neck, back, lower back, and joint pain.
  • Post-traumatic pain following injury or surgery.
  • Nerve-related pain, fibromyalgia, and neuralgia.
In addition to pain management, Dr. Popov helps patients with:
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  • High blood pressure and metabolic conditions such as diabetes.
  • Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

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Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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She integrates medical analysis, psychological insight, and real-life behaviour change tools to offer treatment plans tailored to each patient’s biochemistry, mental state, and lifestyle.

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Her approach is never one-size-fits-all – each consultation begins with a deep dive into your unique health history, test results, and emotional landscape. Consultations are available in Ukrainian, Polish, and Russian.
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