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Tetralisal

Tetralisal

Ask a doctor about a prescription for Tetralisal

5.0(8)
Doctor

Anastasiia Shalko

Family medicine12 years of experience

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Tetralisal

Leaflet attached to the packaging: patient information

Tetralysal, 300 mg, hard capsules

Lymecycline

Read the leaflet carefully before taking the medicine, as it contains important information for the patient

  • Keep this leaflet, you may need to read it again.
  • In case of any doubts, consult a doctor or pharmacist.
  • This medicine has been prescribed specifically for you. Do not pass it on to others. The medicine may harm another person, even if their symptoms are the same.
  • If the patient experiences any side effects, including any side effects not listed in the leaflet, they should tell their doctor or pharmacist. See section 4.

Table of contents of the leaflet

  • 1. What is Tetralysal and what is it used for
  • 2. Important information before taking Tetralysal
  • 3. How to take Tetralysal
  • 4. Possible side effects
  • 5. How to store Tetralysal
  • 6. Contents of the pack and other information

1. What is Tetralysal and what is it used for

Tetralysal is an antibiotic belonging to the tetracycline group. In the treatment of acne, it works:

  • as an antibacterial agent against the microorganism Propionibacterium acnes;
  • as an anti-inflammatory agent (by inhibiting the activity of certain types of white blood cells);
  • by inhibiting the bacterial enzyme that produces free fatty acids, which have an irritating effect. This reduces the number of inflammatory lesions on the skin.

Indications for the use of Tetralysal:

  • common acne of moderate and severe degree, with inflammatory lesions in the form of papules, pustules, nodules, cysts, and infiltrates;
  • rosacea.

2. Important information before taking Tetralysal

When not to take Tetralysal:

  • if the patient is hypersensitive (allergic) to lymecycline or any of the other ingredients of the medicine (listed in section 6);
  • if the patient is allergic to other tetracycline antibiotics;
  • if the patient is taking retinoids (used to treat skin diseases);
  • in children under 8 years of age (due to the risk of permanent tooth discoloration and enamel hypoplasia);
  • during pregnancy and breastfeeding.

Warnings and precautions

Before starting treatment with Tetralysal, discuss it with your doctor.

Stop taking Tetralysal if severe headaches occur. Taking Tetralysal may cause esophageal irritation and ulceration; to avoid this, drink plenty of fluids with the medicine. In case of strong exposure to sunlight or other sources of ultraviolet radiation, the medicine may rarely cause skin reactions (phototoxic effect). Such an effect has been demonstrated after taking high doses of the medicine (1200 mg/day) and concurrent strong exposure to UV radiation (sunbathing, solarium). However, during treatment, it is recommended to avoid sunlight and other sources of ultraviolet radiation (e.g., solarium). If skin changes occur, especially redness or blisters, seek medical attention immediately, as this may be the beginning of rare, life-threatening severe skin complications. If diarrhea occurs during or after treatment with the medicine, seek medical attention immediately. Diarrhea may be a symptom of pseudomembranous colitis caused by toxins of excessively multiplying bacteria Clostridium difficile. Colitis can be mild or severe. Mild cases usually resolve after discontinuation of the medicine. In more severe cases, the doctor may prescribe metronidazole or vancomycin. Do not take medicines that slow down bowel movements or have a constipating effect. If the patient has myasthenia gravis (a disease characterized by muscle weakness), lymecycline treatment may exacerbate the symptoms of this disease. Caution should be exercised when using Tetralysal in patients with myasthenia gravis. If the patient has systemic lupus erythematosus, they should consult a doctor before taking this medicine. Do not take expired medicine, as it may cause kidney damage. The medicine should be used with caution in patients with impaired kidney or liver function. Consult a doctor, even if the above conditions have occurred in the past.

Children and adolescents

Do not give Tetralysal to children under 8 years of age due to the risk of permanent tooth discoloration and enamel hypoplasia.

Tetralysal and other medicines

Tell your doctor about all medicines you are taking or have recently taken, as well as any medicines you plan to take. Interaction studies with lymecycline and other medicines have been conducted only in adults. Tell your doctor about the following medicines you are taking:

  • blood thinners, e.g., warfarin
  • HIV treatments, e.g., didanosine
  • other acne treatments
  • other antibiotics, including penicillins
  • oral retinoids and products containing vitamin A (more than 10,000 IU/day): risk of increased intracranial pressure
  • diuretics

Tell your doctor if you are taking any medicines containing lithium, as this medicine may increase lithium levels in the blood. Do not take the following medicines at the same time as Tetralysal, as they may affect the proper functioning of the medicine. Wait at least 2 hours before or after taking Tetralysal with the following types of products:

  • antacids
  • iron-containing products
  • antiepileptics, including barbiturates, e.g., phenobarbital, phenytoin, carbamazepine
  • medicines that reduce stomach acid, e.g., cimetidine and ranitidine
  • antacids (hydroxides and salts of magnesium, aluminum, and calcium), activated charcoal, cholestyramine, bismuth chelates, sucralfate.

The use of methoxyflurane with Tetralysal is not recommended due to the risk of fatal kidney intoxication. Tell your doctor if you have a planned surgery that requires anesthesia, as tetracyclines cannot be used with certain types of anesthetics. Tetralysal may enhance the effect of oral anticoagulants (coumarin derivatives), cytostatics, oral antidiabetic drugs, glucocorticosteroids. It may interfere with the determination of catecholamines and glucose (reduction methods) in urine, giving falsely elevated results.

Tetralysal with food and drink

See section 3.

Pregnancy and breastfeeding

Tetralysal must not be takenduring pregnancy and breastfeeding. The use of tetracycline-like medicines may affect the normal growth of developing teeth and cause permanent tooth discoloration. If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, consult your doctor before taking this medicine.

Driving and using machines

Tetralysal does not affect the ability to drive and use machines.

3. How to take Tetralysal

Always take this medicine exactly as your doctor has told you. If you are not sure, consult your doctor or pharmacist. Adults The recommended dose is:

  • for the treatment of common acne:300 mg (one Tetralysal capsule) per day for 12 weeks;
  • for the treatment of rosacea:initially 600 mg (one Tetralysal capsule twice a day) for 10 days, then 300 mg (one Tetralysal capsule) once a day for 3 to 6 months.

Swallow the capsules with a large amount of water, sitting upright, to avoid esophageal damage. Taking the medicine with food, including milk, does not significantly affect its absorption. Capsules containing 150 mg of the active substance are also available. Your doctor will tell you how long to take Tetralysal.

Use in children

Do not give Tetralysal to children under 8 years of age.

Taking more than the recommended dose of Tetralysal

Overdose may damage the liver. If you have taken more than the recommended dose, seek medical attention immediately.

Missing a dose of Tetralysal

Do not take a double dose to make up for a missed dose.

Stopping treatment with Tetralysal

Do not stop treatment too early, as symptoms may return. Always consult your doctor if you are considering stopping treatment with Tetralysal. If you have any further questions about the use of this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, Tetralysal can cause side effects, although not everybody gets them.

The following side effects are listed by frequency of occurrence.

Frequent (occurring in 1 to 10 in 100 patients)

  • Nausea
  • Abdominal pain
  • Diarrhea
  • Headache

Frequency not known (frequency cannot be estimated from available data)

  • Changes in blood cell count
  • Vision disturbances*
  • Double vision
  • Permanent vision loss
  • Tongue inflammation
  • Enteritis
  • Vomiting
  • Upper abdominal pain
  • Small intestine and colon inflammation
  • Pseudomembranous colitis
  • Pancreatitis
  • Fever
  • Jaundice (yellowing of the skin or eyes)
  • Hepatitis
  • Changes in laboratory test results (blood tests, liver enzyme tests)
  • Allergic reactions (skin itching, especially around the eyes and mouth)
  • Skin itching, rash, or urticaria
  • Sudden, severe allergic reactions with a generalized feeling of being unwell
  • Blastomycosis, candidiasis (thrush)
  • Vaginitis
  • Increased intracranial pressure
  • Dizziness
  • Sensitivity to sunlight
  • Toxic epidermal necrolysis
  • Formation of pimples or skin peeling over large areas, ulceration, or changes in the mouth, lips, genital, and anal areas (Stevens-Johnson syndrome)
  • Depression
  • Nightmares

*Clinical symptoms such as vision disturbances or headaches may be caused by increased intracranial pressure. If symptoms of increased intracranial pressure occur during lymecycline treatment, discontinue the medicine. During tetracycline treatment, mild increased intracranial pressure has been reported, which may manifest as headache, vomiting, vision disturbances, including blurred vision, flashes (dark spots or flashes in the field of vision), diplopia (double vision), or permanent vision loss. Additionally, the following side effects may occur during treatment with other medicines in the same group as Tetralysal (tetracyclines):

  • tooth discoloration and enamel hypoplasia if the medicine is given to children under 8 years of age;
  • changes in blood test results (decrease in red blood cell count, increase in certain white blood cell counts);
  • hyperazotemia (excessive levels of nitrogen compounds in the blood), which may be intensified by concurrent use of diuretics.

Systemic lupus erythematosus and pancreatitis have been reported in association with tetracycline treatment. Stop taking Tetralysal if symptoms of increased intracranial pressure occur.

Reporting side effects

If you experience any side effects, including any side effects not listed in this leaflet, tell your doctor or pharmacist. Side effects can be reported directly to the Department of Drug Safety Monitoring of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products Al. Jerozolimskie 181C 02-222 Warsaw, Poland Tel.: +48 22 49 21 301 Fax: +48 22 49 21 309 Website: https://smz.ezdrowie.gov.pl Side effects can also be reported to the marketing authorization holder. By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Tetralysal

Keep the medicine out of the sight and reach of children. Do not use this medicine after the expiry date stated on the carton. The expiry date refers to the last day of the month. There are no special precautions for storage. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Tetralysal contains

  • The active substance is lymecycline. One hard capsule contains 408 mg of lymecycline, equivalent to 300 mg of tetracycline.
  • The other ingredients are: magnesium stearate, colloidal hydrated silica.
  • Hard capsule shell: gelatin, titanium dioxide (E 171), erythrosine (E 127), quinoline yellow (E 104), indigo carmine (E 132).

What Tetralysal looks like and contents of the pack

Tetralysal is available in the form of red-yellow hard capsules. The pack contains 16 or 28 capsules.

Marketing authorization holder

Galderma Polska Sp. z o.o. ul. Puławska 145 02-715 Warsaw, Poland tel.: 22 331 21 80

Manufacturer

Laboratoires Sophartex S.A. 21, rue de Pressoir, 28500 Vernouillet France Date of last revision of the leaflet:07/2021

  • Country of registration
  • Active substance
  • Prescription required
    Yes
  • Manufacturer
  • Importer
    Laboratoires Sophartex S.A.
  • Alternatives to Tetralisal
    Dosage form: Capsules, 150 mg
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    Prescription required
    Dosage form: Capsules, 300 mg
    Active substance: lymecycline
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Alternatives to Tetralisal in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Tetralisal in Hiszpania

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Active substance: tigecycline
Prescription required
Dosage form: KAPSUŁKA, 50 mg
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Prescription required

Online doctors for Tetralisal

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Tetralisal – subject to medical assessment and local rules.

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Anastasiia Shalko

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Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Experience and qualifications:

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  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Her work also includes developing personalised immunisation plans and supporting families with long-term preventive care.

Known for her structured clinical approach and clear communication, Dr Liudmyla Boichuk offers patients of all ages comprehensive, reliable and evidence-based medical care.

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5.0(2)
Doctor

Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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€50
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