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Silifar

Ask a doctor about a prescription for Silifar

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Doctor

Karim BenHarbi

General medicine8 years of experience

Dr. Karim Ben Harbi is a licensed general practitioner based in Italy. He provides online consultations for adults and children, combining international clinical experience with evidence-based medicine. His care approach is focused on accurate diagnosis, preventive care, and personalised health guidance.

Dr. Ben Harbi received his medical degree from Sapienza University in Rome. His training included hands-on experience in diverse settings — tropical medicine, rural healthcare, and urban outpatient practice. He also conducted clinical research in microbiology, exploring the role of the gut microbiome in chronic gastrointestinal issues.

You can consult Dr. Ben Harbi for:

  • General health concerns, prevention, and primary care.
  • Hypertension, type 1 and type 2 diabetes, metabolic issues.
  • Cold, cough, flu, respiratory infections, sore throat, fever.
  • Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
  • Skin rashes, mild allergic reactions, basic dermatological complaints.
  • Medication guidance, treatment adjustments, prescription review.
  • Paediatric concerns — fever, infections, general well-being.
  • Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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Doctor

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Silifar

Leaflet attached to the packaging: information for the user

Sylifar

140 mg of silymarin in terms of silybin, hard capsules

Silybi mariani extractum siccum raffinatum et normatum

Please read the contents of the leaflet carefully before using the medicine, as it contains important information for the patient.

This medicine should always be used exactly as described in the patient leaflet or as directed by a doctor or pharmacist.

  • Please keep this leaflet, so that you can read it again if you need to.
  • If you need advice or additional information, you should consult a pharmacist.
  • If the patient experiences any side effects, including any possible side effects not listed in the leaflet, they should inform their doctor or pharmacist. See section 4.
  • If after 2 weeks of use, there is no improvement or the patient feels worse, they should contact their doctor.

Table of contents of the leaflet

  • 1. What is Sylifar and what is it used for
  • 2. Important information before using Sylifar
  • 3. How to use Sylifar
  • 4. Possible side effects
  • 5. How to store Sylifar
  • 6. Contents of the packaging and other information

1. What is Sylifar and what is it used for

Sylifar is a traditional herbal medicinal product for use in specified indications, resulting solely from its long-term use.
Sylifar contains a dry extract of milk thistle fruit in its composition. The active substance of milk thistle fruit is a complex of flavonoids called silymarin, which includes, among others, silybin.
The traditional herbal medicinal product is used for the symptomatic treatment of digestive disorders, feelings of fullness and indigestion, as well as to support liver function, after excluding serious diseases by a doctor.
If after 2 weeks, there is no improvement or the patient feels worse, they should consult their doctor.

2. Important information before using Sylifar

When not to use Sylifar:

Warnings and precautions

Before starting to use Sylifar, the patient should discuss it with their doctor or pharmacist.
The medicine should not be used to treat acute poisonings.
Harmful factors for the liver (such as alcohol) should be avoided.
If symptoms of jaundice (light to dark yellow discoloration of the skin, yellow discoloration of the eyes) occur, the patient should consult their doctor.
If the symptoms worsen during the use of the medicinal product, the patient should consult their doctor.

Children and adolescents

Due to the lack of data confirming the safety of use, it is not recommended to use the medicine in children under 18 years of age.

Sylifar and other medicines

The patient should tell their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.
No interactions have been found during use with other medicines.

Sylifar with food, drink, and alcohol

It is recommended to use the medicine before a meal.

Pregnancy, breastfeeding, and fertility

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before using this medicine.
The safety of the medicinal product during pregnancy and breastfeeding has not been established.
The use of the medicine during pregnancy and breastfeeding is not recommended due to the lack of sufficient data.

Driving and using machines

No studies have been conducted on the effect of silymarin on the ability to drive and use machines.

Sylifar contains orange yellow (E110) and azorubine (E122).

The medicine may cause allergic reactions.
The medicine contains less than 1 mmol (23 mg) of sodiumper recommended dose, which means the medicine is considered "sodium-free".

3. How to use Sylifar

This medicine should always be used exactly as described in the patient leaflet or as directed by a doctor or pharmacist. If in doubt, the patient should consult their doctor or pharmacist.
At the beginning of treatment, it is recommended to take 1 capsule 3 times a day (which corresponds to 420 mg of silymarin). As a maintenance dose, it is recommended to take 1 capsule 2 times a day (which corresponds to 280 mg of silymarin).
The medicine should be taken whole, without chewing or crushing, before a meal, with a small amount of liquid.
The patient should consult their doctor if the symptoms persist for more than 2 weeks after starting the use of the medicine.

Use in children

Due to the lack of data confirming the safety of use, it is not recommended to use the medicine in children under 18 years of age.

Overdose of Sylifar

There are no data on the symptoms of overdose.

Missed dose of Sylifar

A double dose should not be taken to make up for a missed dose.

Stopping the use of Sylifar

In case of any further doubts related to the use of this medicine, the patient should consult their doctor or pharmacist.

4. Possible side effects

Like all medicines, Sylifar can cause side effects, although not everybody gets them.
During use, mild gastrointestinal disorders, such as dry mouth, nausea, stomach upset, stomach irritation, and diarrhea, may occur. Headache, allergic reactions (skin inflammation, hives, rash, itching, anaphylaxis, asthma), have also been observed. The frequency of these side effects is unknown.

Reporting side effects

If any side effects occur, including any side effects not listed in the leaflet, the patient should inform their doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181 C, 02-222 Warsaw, Tel. 48 22 49 21 301, fax 48 22 49 21 309, e-mail: [email protected].
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will allow for more information to be gathered on the safety of the medicine.

5. How to store Sylifar

Store in a temperature below 30°C.
Store in a place out of sight and reach of children.
Do not use Sylifar after the expiry date stated on the packaging. The expiry date refers to the last day of the specified month.
Medicines should not be disposed of via wastewater or household waste containers. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Contents of the packaging and other information

What Sylifar contains

The active substance of Sylifar is a dry, purified, and standardized extract of milk thistle fruit (Silybi mariani extractum siccum raffinatum et normatum).

  • One capsule contains 241.35 mg of extract (in the form of a dry, purified extract from Silybum marianum(L.) Gaertn., fructus (milk thistle fruit) (22-27:1), which corresponds to 140 mg of silymarin in terms of silybin. The extraction solvent is aceton 95% (V/V).

The nominal content of silymarin in terms of silybin in the extract is 58% (m/m).

  • The other ingredients are: Capsule content: microcrystalline cellulose, colloidal anhydrous silica, meglumine, sodium carboxymethyl cellulose type A, magnesium stearate. Capsule shell: gelatin, titanium dioxide (E171), quinoline yellow (E104), azorubine (E122), patent blue V (E131), orange yellow FCF (E110).

What Sylifar looks like and what the packaging contains

Sylifar are red and dark green hard capsules containing a brown mixture.
The hard capsules are packaged in PVC/PVDC/Aluminum blisters, together with the patient leaflet, in a cardboard box.
The packaging contains 10, 20, 30, 60, or 100 hard capsules.
Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Biofarm Sp. z o.o.
ul. Wałbrzyska 13
60-198 Poznań
Tel. +48 61 66 51 500

Date of the last update of the leaflet:

  • Country of registration
  • Active substance
  • Prescription required
    No
  • Manufacturer
  • Importer
    Biofarm Sp. z o.o.
  • Alternatives to Silifar
    Dosage form: Tablets, 150 mg
    Active substance: silymarin
    Prescription not required
    Dosage form: Tablets, 150 mg
    Active substance: silymarin
    Prescription not required
    Dosage form: Tablets, 150 mg
    Active substance: silymarin
    Prescription not required

Alternatives to Silifar in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Silifar in Ukraine

Dosage form: capsules, 70 mg, 10 capsules in a blister
Active substance: silymarin
Dosage form: capsules, capsules 140mg
Active substance: silymarin
Dosage form: capsules, 140 mg
Active substance: silymarin
Manufacturer: MADAUS GmbH
Prescription not required
Dosage form: tablets, 22.5 mg
Active substance: silymarin
Prescription not required
Dosage form: capsules, 90 mg capsules in blister
Active substance: silymarin
Manufacturer: AT "Sofarma
Prescription not required

Alternative to Silifar in Spain

Dosage form: CAPSULE, 100 mg Dry extract of milk thistle (equivalent to 80 mg of silymarin)
Active substance: silymarin
Prescription required
Dosage form: CAPSULE, 150 mg silymarin
Active substance: silymarin
Prescription required
Dosage form: CAPSULE, 300 mg
Prescription not required
Dosage form: INJECTABLE PERFUSION, 350 mg sodium silibinate
Prescription required
Dosage form: TABLET, 4.6 mg dry extract Cynara scolimus (1:30-31); 1.2 mg dry extract Taraxacum officinalis (1:17-18); 0.7 mg dry extract Peumus boldus (1:10-11); 3.2 mg dry extract Silibum marianum (1:2-2.1)
Prescription not required
Dosage form: CAPSULE, 390 mg
Prescription not required

Online doctors for Silifar

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Silifar – subject to medical assessment and local rules.

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Doctor

Karim BenHarbi

General medicine8 years of experience

Dr. Karim Ben Harbi is a licensed general practitioner based in Italy. He provides online consultations for adults and children, combining international clinical experience with evidence-based medicine. His care approach is focused on accurate diagnosis, preventive care, and personalised health guidance.

Dr. Ben Harbi received his medical degree from Sapienza University in Rome. His training included hands-on experience in diverse settings — tropical medicine, rural healthcare, and urban outpatient practice. He also conducted clinical research in microbiology, exploring the role of the gut microbiome in chronic gastrointestinal issues.

You can consult Dr. Ben Harbi for:

  • General health concerns, prevention, and primary care.
  • Hypertension, type 1 and type 2 diabetes, metabolic issues.
  • Cold, cough, flu, respiratory infections, sore throat, fever.
  • Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
  • Skin rashes, mild allergic reactions, basic dermatological complaints.
  • Medication guidance, treatment adjustments, prescription review.
  • Paediatric concerns — fever, infections, general well-being.
  • Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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Anna Biriukova

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Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

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  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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  • Development of tailored treatment plans based on clinical guidelines.

With a patient-centred approach, Dr. Raevskii helps individuals manage both chronic illnesses and complex oncological cases. His consultations are guided by current medical standards and adapted to each patient’s needs.

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  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
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Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

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  • Chronic pain lasting more than 3 months.
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In addition to pain management, Dr. Popov helps patients with:
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Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
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Additional care areas:

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  • Medical advice and follow-up consultations.
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  • Structured support for undiagnosed complaints.
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Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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