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Rupafin

Rupafin

Ask a doctor about a prescription for Rupafin

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Doctor

Tomasz Grzelewski

Dermatology20 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Rupafin

Package Leaflet: Information for the User

Rupafin, 1 mg/ml, Oral Solution

Rupatadine

Read the Package Leaflet Carefully Before Taking the Medication, as it Contains Important Information for the Patient.

  • Keep this Package Leaflet, You May Need to Read it Again.
  • If You Have Any Further Questions, Ask Your Doctor or Pharmacist.
  • This Medication Has Been Prescribed for You Only. Do Not Pass it on to Others. It May Harm Them, Even if Their Symptoms are the Same as Yours.
  • If You Experience Any Side Effects, Including Those Not Listed in this Package Leaflet, Tell Your Doctor or Pharmacist. See Section 4.

Package Leaflet Contents

  • 1. What is Rupafin and What is it Used For
  • 2. Important Information Before Taking Rupafin
  • 3. How to Take Rupafin
  • 4. Possible Side Effects
  • 5. How to Store Rupafin
  • 6. Package Contents and Other Information

1. What is Rupafin and What is it Used For

Rupafin Contains the Active Substance Rupatadine, Which is an Antihistamine.
Rupafin Oral Solution Relieves the Symptoms of Allergic Rhinitis, Such as
Sneezing, Runny Nose, Nasal Congestion, Itchy Eyes and Nose in Children Aged 2 to 11 Years.
Rupafin is Also Used to Relieve the Symptoms of Urticaria (Allergic Skin Rash), Such as Itching and Hives (Local Redness and Swelling of the Skin) in Children Aged 2 to 11 Years.

2. Important Information Before Taking Rupafin

When Not to Take Rupafin

  • If You are Allergic to Rupatadine or Any of the Other Ingredients of this Medication (Listed in Section 6).

Warnings and Precautions

Before Taking Rupafin, Discuss it with Your Doctor or Pharmacist.
If You Have Kidney or Liver Failure, Consult Your Doctor.
Rupafin is Not Recommended for Patients with Kidney or Liver Impairment.
If You Have Low Potassium Levels in the Blood and/or Abnormal Heart Rhythm (Known as Prolonged QTc Interval in the ECG), Which May Occur in Certain Heart Conditions, Consult Your Doctor.

Children

This Medication is Not Intended for Use in Children Under 2 Years of Age or Weighing Less than 10 kg.

Rupafin and Other Medications

Tell Your Doctor or Pharmacist About All Medications You are Currently Taking or Have Recently Taken, as Well as Any Medications You Plan to Take.
If You are Taking Rupafin, Do Not Take Medications Containing Ketokonazole (an Antifungal Medication) or Erythromycin (an Antibiotic).
If You are Taking Medications that Affect the Central Nervous System, Statins (Cholesterol-Lowering Medications), or Midazolam (a Short-Acting Sedative), Consult Your Doctor Before Taking Rupafin.

Rupafin with Food, Drink, and Alcohol

Rupafin Can be Taken with or Without Food.
Do Not Take Rupafin with Grapefruit Juice, as it May Increase the Levels of Rupafin in the Body.
Rupafin at a Dose of 10 mg Does Not Increase Drowsiness Caused by Alcohol.

Pregnancy and Breastfeeding

If You are Pregnant or Breastfeeding, Think You May be Pregnant or are Planning to Have a Baby, Ask Your Doctor or Pharmacist for Advice Before Taking this Medication.

Driving and Using Machines

Rupafin is Not Expected to Affect the Ability to Drive or Use Machines. However, if You are Taking Rupafin for the First Time, Be Cautious and Observe Your Reaction to the Medication Before Driving or Using Machines.

Rupafin Contains Sucrose, Methyl Parahydroxybenzoate, and Propylene Glycol

This Medication Contains Sucrose, Which May be Harmful to Teeth. If You Have Been Diagnosed with Intolerance to Some Sugars, Consult Your Doctor Before Taking this Medication.
This Medication Contains Methyl Parahydroxybenzoate, Which May Cause Allergic Reactions (Possible Late-Stage Reactions).
The Medication Contains 200 mg of Propylene Glycol in Each ml.
Before Administering this Medication to a Child Under 5 Years of Age, Consult Your Doctor or Pharmacist, Especially if the Child is Taking Other Medications Containing Propylene Glycol or Alcohol.
Pregnant or Breastfeeding Women Should Not Take this Medication Without Medical Advice. The Doctor May Decide to Perform Additional Tests on Such Patients.
Patient with Liver or Kidney Impairment Should Not Take this Medication Without Medical Advice. The Doctor May Decide to Perform Additional Tests on Such Patients.
The Medicinal Product Contains Less than 1 mmol (23 mg) of Sodium per 1 ml, i.e., the Medication is Considered "Sodium-Free".

3. How to Take Rupafin

Always Take Rupafin Exactly as Your Doctor Has Told You. If You are Not Sure, Ask Your Doctor or Pharmacist.
Rupafin Oral Solution is for Oral Use Only.
Dosing in Children Weighing 25 kg or More:
5 ml (5 mg of Rupatadine) of Oral Solution Once a Day, with or Without Food.
Dosing in Children Weighing 10 kg or More, but Less than 25 kg:
2.5 ml (2.5 mg of Rupatadine) of Oral Solution Once a Day, with or Without Food.
Your Doctor Will Tell You How Long to Take Rupafin.
Method of Administration:

  • To Open the Bottle, Press the Cap and Turn it in the Opposite Direction of the Clockwise Movement.
  • Take the Syringe and Place it in the Perforated Cork, Turn the Bottle Upside Down.
  • Fill the Syringe with the Prescribed Dose.
  • Administer the Solution Directly from the Measuring Syringe.
  • Wash the Syringe After Use.

Taking More than the Recommended Dose of Rupafin

If You Have Taken More than the Recommended Dose of Rupafin, Contact Your Doctor or Pharmacist Immediately.

Missing a Dose of Rupafin

Do Not Take a Double Dose to Make Up for a Forgotten Dose.

4. Possible Side Effects

Like All Medications, Rupafin Can Cause Side Effects, Although Not Everybody Gets Them.
Common Side Effects (May Affect Up to 1 in 10 People) Include: Headache and Drowsiness. Uncommon Side Effects (May Affect Up to 1 in 100 People) Include: Flu, Pharyngitis, Upper Respiratory Tract Infection, Eosinophilia, Neutropenia, Dizziness, Nausea, Rash, Night Sweats, and Fatigue.

Reporting Side Effects

If You Experience Any Side Effects, Including Those Not Listed in this Package Leaflet, Tell Your Doctor or Pharmacist, or Nurse. Side Effects Can be Reported Directly to the Department of Medicinal Product Monitoring, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181C, 02-222 Warsaw, Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309, Website: https://smz.ezdrowie.gov.pl
Side Effects Can Also be Reported to the Marketing Authorization Holder or Its Representative in Poland.
Reporting Side Effects Will Help to Gather More Information on the Safety of this Medication.

5. How to Store Rupafin

Keep this Medication Out of the Sight and Reach of Children.
There are No Special Precautions for Storage of the Medicinal Product.
Do Not Use this Medication After the Expiry Date Stated on the Bottle and Carton After EXP. The Expiry Date Refers to the Last Day of the Month Stated. The Shelf Life After First Opening is the Same as the Expiry Date on the Carton and Bottle.
Medications Should Not be Disposed of via Wastewater or Household Waste. Ask Your Pharmacist How to Dispose of Medications No Longer Required. This Will Help Protect the Environment.

6. Package Contents and Other Information

What Rupafin Contains

  • The Active Substance is Rupatadine. Each ml Contains 1 mg of Rupatadine (as Rupatadine Fumarate).
  • The Other Ingredients are: Propylene Glycol (E 1520), Citric Acid Anhydrous, Disodium Phosphate Anhydrous, Sodium Saccharin, Sucrose, Methyl Parahydroxybenzoate (E 218), Quinoline Yellow (E 104), Banana Flavor, Purified Water. See Section 2 "Rupafin Contains Sucrose, Methyl Parahydroxybenzoate, and Propylene Glycol".

What Rupafin Looks Like and What the Package Contains

Rupafin is a Clear, Yellow Oral Solution.
Rupafin is Packaged in PET Bottles with an LDPE Connector and an HDPE Child-Resistant Closure in a Cardboard Box. Each Bottle Contains 120 ml of Rupafin Solution. The Package Includes a 5 ml PP/PE Measuring Syringe with 0.25 ml Gradations.

Marketing Authorization Holder

NOUCOR HEALTH, S.A.
Av. Camí Reial, 51-57
08184 Palau-solitá i Plegamans
Barcelona, Spain

Manufacturer

Italfarmaco S.A.
San Rafael, 3
Pol. Ind. Alcobendas
28108 Alcobendas
Spain
NOUCOR HEALTH, S.A.
Av. Camí Reial, 51-57
08184 Palau-solitá i Plegamans
Barcelona, Spain
For More Information, Contact the Marketing Authorization Holder's Representative:
Zentiva Polska Sp. z o. o.
ul. Bonifraterska 17
00-203 Warsaw
Tel. (22) 375 92 00

This Medicinal Product is Authorized in the Member States of the European Economic Area Under the Following Names:

Rupatall
Belgium, Luxembourg
Rinialer
Malta, Portugal
Rupafin
Austria, Bulgaria, Croatia, Cyprus, Denmark, Estonia, Greece, Spain,
Netherlands, Ireland, Iceland, Liechtenstein, Lithuania, Latvia, Germany, Norway,
Poland, Slovakia, Slovenia, Italy
Rupatadine
United Kingdom
Wystamm
France
Tamalis
Czech Republic, Romania, Hungary
Pafinur
Finland, Sweden
Date of Last Revision of the Package Leaflet:April 2024

Alternatives to Rupafin in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Rupafin in Испания

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Alternative to Rupafin in Украина

Dosage form: таблетки, таблетки 10 мг
Active substance: рупатадин
Manufacturer: NOUKOR HELS, S.A
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Dosage form: раствор, 1 мг/мл; 120 мл во флаконе
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Active substance: рупатадин
Prescription required
Dosage form: раствор, 1 мг/мл, 100 мл во флаконе
Active substance: рупатадин
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Online doctors for Rupafin

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Rupafin – subject to medical assessment and local rules.

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Doctor

Tomasz Grzelewski

Dermatology20 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Her approach is never one-size-fits-all – each consultation begins with a deep dive into your unique health history, test results, and emotional landscape. Consultations are available in Ukrainian, Polish, and Russian.
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Dr. Correa combines medical knowledge with an aesthetic and holistic approach to help patients improve both health and quality of life.

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Experience and qualifications:

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Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Patients commonly consult Dr Marta Reguero Capilla for:

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Dr Reguero Capilla works in a structured and attentive manner, explaining medical decisions clearly and helping patients make informed choices about their own health or their child’s care.

When clinically appropriate, she may provide recommendations for further tests or referrals that patients can use within Spanish medical networks, including Sanitas and DKV, in accordance with the terms and conditions of those services.

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