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PROTAMINE 14000 IU/ml Solution

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Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Protamine sulfate Leo Pharma

Contents of the leaflet

  1. PATIENT INFORMATION LEAFLET
  2. Leaflet accompanying the packaging: patient information
  3. Protamine sulfate LEO Pharma, 1400 anti-heparin IU/mL
    1. Read the leaflet carefully before using the medicine, as it contains important information for the patient.
    2. Table of contents of the leaflet
  4. What is Protamine sulfate LEO Pharma and what is it used for
  5. Important information before using Protamine sulfate LEO Pharma
    1. When not to use Protamine sulfate LEO Pharma
    2. Warnings and precautions
    3. Children and adolescents
    4. Protamine sulfate LEO Pharma and other medicines
    5. Pregnancy and breastfeeding
    6. Driving and using machines
    7. Protamine sulfate LEO Pharma contains sodium
  6. How to use Protamine sulfate LEO Pharma
    1. Using more than the recommended dose of Protamine sulfate LEO Pharma
  7. Possible side effects
    1. Severe side effects
    2. Less severe side effects that have been observed during administration of Protamine sulfate LEO Pharma:
    3. Reporting side effects
  8. How to store Protamine sulfate LEO Pharma
  9. Contents of the pack and other information
    1. What Protamine sulfate LEO Pharma contains
    2. What Protamine sulfate LEO Pharma looks like and contents of the pack
    3. Marketing authorization holder and manufacturer
    4. Marketing authorization holder
    5. Manufacturer
    6. Date of last revision of the leaflet:
    7. Protamine sulfate LEO Pharma
    8. 1400 anti-heparin IU/mL (which corresponds to 10 mg/mL) solution for injection/infusion
    9. 1 mL contains 1400 anti-heparin IU of protamine sulfate (10 mg)
    10. 5 mL contains 7000 anti-heparin IU of protamine sulfate (50 mg)
    11. For more information, see the Summary of Product Characteristics (SPC).
    12. Dosage and administration
    13. Neutralization of heparin
    14. Neutralization of low molecular weight heparin (LMWH)
    15. Cardiopulmonary bypass procedures
    16. Special precautions for disposal

PATIENT INFORMATION LEAFLET

Leaflet accompanying the packaging: patient information

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

Protamine sulfate LEO Pharma, 1400 anti-heparin IU/mL

(which corresponds to 10 mg/mL), solution for injection/infusion
Protamine sulfate

Read the leaflet carefully before using the medicine, as it contains important information for the patient.

  • Keep this leaflet, you may need to read it again.
  • This product is usually administered by a doctor or nurse. If you have any doubts, consult your doctor, nurse, or pharmacist.
  • If the patient experiences any side effects, including any side effects not listed in this leaflet, tell your doctor, pharmacist, or nurse. See section 4.

Table of contents of the leaflet

  • 1. What is Protamine sulfate LEO Pharma and what is it used for
  • 2. Important information before using Protamine sulfate LEO Pharma
  • 3. How to use Protamine sulfate LEO Pharma
  • 4. Possible side effects
  • 5. How to store Protamine sulfate LEO Pharma
  • 6. Contents of the pack and other information

1. What is Protamine sulfate LEO Pharma and what is it used for

The active substance is protamine sulfate, which is used as an antidote to counteract the effects of heparin and low molecular weight heparin (LMWH) and reduce the impact of these substances on the body.
Heparins are used to prevent blood clotting and may cause bleeding.
The patient may receive this medicine:

  • To help stop bleeding caused by heparin/LMWH
  • To prevent frequent bleeding, if the patient has been treated with heparin/LMWH and is to undergo surgery
  • To reverse the effects of heparin used in certain types of heart surgery.
Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

2. Important information before using Protamine sulfate LEO Pharma

When not to use Protamine sulfate LEO Pharma

  • if the patient is allergic to protamine sulfate or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Before starting treatment with Protamine sulfate LEO Pharma, discuss it with your doctor, pharmacist, or nurse if the patient:

  • is diabetic using insulin (especially protamine insulin)
  • is allergic to fish
  • is an infertile man (cannot have children) or has undergone a vasectomy (an operation that makes a man infertile)
  • has previously been treated with protamine sulfate, protamine insulin, or protamine chloride.

Children and adolescents

Protamine sulfate LEO Pharma is not indicated for use in children and adolescents.

Protamine sulfate LEO Pharma and other medicines

Tell your doctor or pharmacist about all medicines the patient is taking, has recently taken, or might take.

Pregnancy and breastfeeding

Pregnancy
If the patient is pregnant, thinks she may be pregnant, or plans to have a baby, she should consult her doctor, nurse, or pharmacist before using this medicine.
There is no available information on the use of this product in pregnant women.
Do not use Protamine sulfate LEO Pharma unless absolutely necessary.
Breastfeeding
If the patient is breastfeeding, she should consult her doctor, nurse, or pharmacist before using this medicine.
There is no available information on the use of this medicine in breastfeeding women.
If treatment with protamine sulfate LEO Pharma is necessary, breastfeeding should be discontinued.

Driving and using machines

Protamine sulfate LEO Pharma has no or negligible influence on the ability to drive and use machines.

Protamine sulfate LEO Pharma contains sodium

The medicine contains less than 1 mmol (23 mg) of sodium per 5 mL, which means it is essentially 'sodium-free'.

3. How to use Protamine sulfate LEO Pharma

The doctor will decide what dose of Protamine sulfate LEO Pharma is suitable for the patient.
This depends on the results of blood tests to determine how much heparin needs to be counteracted.
Protamine sulfate LEO Pharma is intended for intravenous administration and can be administered by slow injection (over about 10 minutes) into a vein or added to an intravenous infusion solution.
The patient may need additional doses, especially if it is necessary to counteract the effects of LMWH or if the operation is prolonged.
No more than 5 mL of this medicine will be administered in any 10-minute period.

This may interfere with the blood clotting process by prolonging the time it takes for the blood to clot.
If you have any further doubts about the use of this medicine, consult your doctor, pharmacist, or nurse.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Severe side effects

If you experience any of the following symptoms, contact your doctor, nurse, or local hospital immediately for emergency assistance:

  • Severe allergic reaction. Symptoms include severe breathing difficulties, wheezing, swelling of the face and lips, heart problems, and collapse (fainting due to low blood pressure)
  • High blood pressure in the lungs. Symptoms include severe breathing difficulties
  • Severe and prolonged low blood pressure. Symptoms include slow heart rate, blue skin, feeling of fainting or collapse (especially if Protamine sulfate LEO Pharma is administered too quickly)

Less severe side effects that have been observed during administration of Protamine sulfate LEO Pharma:

  • Low blood pressure. Symptoms include dizziness
  • Vomiting
  • Back pain
  • Bleeding
  • Allergic reaction, similar to hives or other skin rashes. Symptoms include feeling of warmth, skin redness, shortness of breath, and swelling of the deeper layers of the skin (sometimes with swelling of the tongue and airways).

Reporting side effects

If you experience any side effects, including any side effects not listed in this leaflet, tell your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Adverse Reaction Monitoring of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C, 02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl.
Side effects can also be reported to the marketing authorization holder.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Protamine sulfate LEO Pharma

  • Keep the medicine out of the sight and reach of children.
  • Do not use this medicine after the expiry date stated on the carton and label after EXP. The expiry date refers to the last day of the month stated.
  • This medicine does not require any special storage conditions.
  • Use immediately after opening the ampoule.
  • Any remaining solution should be discarded.
  • Only use if the solution is clear and the ampoule is intact.
  • After dilution for slow intravenous infusion, the mixture should be used immediately.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Protamine sulfate LEO Pharma contains

  • The active substance is protamine sulfate. 1 mL contains 1400 anti-heparin IU of protamine sulfate (10 mg), 5 mL contains 7000 anti-heparin IU of protamine sulfate (50 mg).
  • The other ingredients are sodium chloride, hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment), and water for injections.

What Protamine sulfate LEO Pharma looks like and contents of the pack

This product is a solution for injection/infusion, which is a clear, colorless liquid.
Ampoules of 5 mL. Pack of 5 ampoules.
Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

LEO Pharma A/S
Industriparken 55
2750 Ballerup
Denmark

Manufacturer

CENEXI
52, rue Marcel et Jacques Gaucher
94120 Fontenay-sous-Bois
France
To obtain more information on this medicine, contact the local representative of the marketing authorization holder:
LEO Pharma Sp. z o.o.
ul. Marynarska 15
02-674 Warsaw
Phone: 22 244 18 40
This medicine is authorized in the Member States of the European Economic Area under the following names:
Protaminsulfat LEO Pharma: Austria, Denmark, Finland, Germany, Iceland, Norway, Sweden, Czech Republic, Slovakia
Protamine sulfaat LEO Pharma: Belgium, Netherlands
Protamine sulfate LEO Pharma: Estonia, Greece, Ireland, Lithuania, Luxembourg, Malta
Sulfato de protamina LEO Pharma: Portugal
Protaminijev sulfat LEO Pharma: Slovenia
Protamina sulfato LEO Pharma: Spain
Protamina solfato LEO Pharma: Italy

Date of last revision of the leaflet:

<------------------------------------------------------------------------------------------------------------------------>
Information intended for healthcare professionals only:

Protamine sulfate LEO Pharma

1400 anti-heparin IU/mL (which corresponds to 10 mg/mL) solution for injection/infusion

1 mL contains 1400 anti-heparin IU of protamine sulfate (10 mg)

5 mL contains 7000 anti-heparin IU of protamine sulfate (50 mg)

For more information, see the Summary of Product Characteristics (SPC).

Therapeutic indications:Protamine sulfate may be used to counteract the anticoagulant effect of heparin or LMWH (see SPC).

Dosage and administration

Protamine sulfate is administered by slow intravenous injection over a period of about 10 minutes or as a continuous, slow infusion. The maximum single injection (bolus dose) should not exceed 5 mL (7000 anti-heparin IU/50 mg of protamine sulfate). It is best if the dose is based on coagulation tests. For this purpose, the activated partial thromboplastin time (APTT), activated clotting time (ACT), anti-Xa test, and protamine neutralization test are suitable. Coagulation tests are usually performed 5 to 15 minutes after administration of protamine sulfate. Further doses may be required, as protamine sulfate is eliminated from the blood more quickly than heparin, and especially LMWH. Prolonged absorption after subcutaneous administration of heparin or LMWH may also indicate the need for multiple doses.

Neutralization of heparin

1 mL of Protamine sulfate LEO Pharma (10 mg of protamine sulfate) neutralizes approximately 1400 IU of heparin. Since heparin has a relatively short half-life after intravenous administration (from 30 minutes to 2 hours), the dose of protamine sulfate should be adjusted based on the time elapsed since the discontinuation of intravenous heparin administration. The dose of protamine sulfate in relation to the amount of heparin administered should be reduced if more than 15 minutes have passed since the end of intravenous heparin administration.

Neutralization of low molecular weight heparin (LMWH)

Typically, a dose of 1 mL of Protamine sulfate LEO Pharma (10 mg of protamine sulfate) per 100 anti-Xa IU of LMWH is recommended. Protamine sulfate neutralizes different LMWHs to varying degrees; therefore, for each LMWH, the manufacturer's own guidelines should be consulted in case of overdose. Protamine sulfate only partially neutralizes the anti-Xa activity induced by LMWH, and neutralization will not be more effective if higher doses of protamine sulfate are administered than recommended. The risk of incomplete neutralization with a single injection of protamine sulfate exists when neutralizing subcutaneously administered LMWH. The absorption phase from the injection site then leads to the release of additional LMWH into the circulation (the so-called "depot effect"). In such cases, repeated administration of protamine sulfate or a continuous, slow intravenous infusion may be necessary. When estimating the required dose of protamine sulfate, the half-life of LMWH in relation to the time elapsed since the last dose of LMWH should also be taken into account.

Cardiopulmonary bypass procedures

It is recommended that doses of protamine sulfate be based on coagulation tests. The activated partial thromboplastin time (APTT), activated clotting time (ACT), anti-Xa, and protamine neutralization test at the bedside are suitable for this purpose. Coagulation tests are usually performed 5 to 15 minutes after administration of protamine sulfate. Generally, a dose of 0.1 mL to 0.2 mL (1-2 mg) of Protamine sulfate LEO Pharma is administered intravenously per 100 units of heparin administered.

Special precautions for disposal

Use immediately after opening the ampoule.
Any remaining solution should be discarded.
The medicine can only be used if the solution is clear, without visible particles, and the ampoule is intact. Any unused product or waste material should be disposed of in accordance with local requirements.
Protamine sulfate LEO Pharma can be administered in a slow intravenous infusion, in which case sodium chloride 9 mg/mL should be used. Such mixtures should not be stored.

Online doctors for Protamine sulfate Leo Pharma

Discuss questions about Protamine sulfate Leo Pharma, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
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Doctor
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Yevgen Yakovenko

Family medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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5.0(3)

Lina Travkina

Family medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Abdullah Alhasan

General medicineCardiology11 years of experience

Dr. Abdullah Alhasan is a physician specialising in cardiology and general medicine, with international clinical experience and a commitment to evidence-based care. He offers online consultations for adults, focusing on both acute symptoms and long-term health management.

Main areas of consultation:

  • Chest pain, shortness of breath, heart palpitations, high blood pressure
  • Hypertension control and cardiovascular disease prevention
  • Interpretation of ECG, blood tests, and Holter monitor results
  • Management of heart failure and coronary artery disease
  • General medical issues: infections, fever, fatigue, gastrointestinal symptoms
  • Guidance on diagnostics, treatment plans, and medication adjustments
Dr. Alhasan’s approach is based on thorough assessment, clear communication, and personalised care – helping patients understand their health and make informed decisions about their treatment.
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Dmytro Horobets

Family medicineEndocrinology7 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Doctor
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Duarte Meneses

Family medicineGeneral medicine5 years of experience

Dr. Duarte Meneses is a licensed family medicine and general practice doctor based in Portugal, with additional expertise in occupational health. He provides online consultations for adults, offering medical support for both acute symptoms and chronic health conditions.

  • Common symptoms such as fever, sore throat, cough, fatigue, or digestive issues
  • Chronic conditions including hypertension, diabetes, high cholesterol, and thyroid problems
  • Mental health concerns such as stress, sleep issues, anxiety, and burnout
  • Preventive care: health check-ups, lifestyle advice, and follow-up for existing conditions
  • Work-related health questions, sick leave documentation, and medical guidance for returning to work
Dr. Meneses graduated from the University of Beira Interior and has years of experience working with diverse patient populations. He is fluent in Portuguese, English, Spanish, and French.

His approach is friendly, clear, and focused on delivering practical medical advice tailored to each patient’s needs.

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Mar Tabeshadze

EndocrinologyGeneral medicine11 years of experience

Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

  • Diagnostic consultations for suspected endocrine disorders
  • Management of thyroid conditions, including in pregnant women
  • Early detection and treatment of type 1 and type 2 diabetes, with personalised therapy plans
  • Obesity treatment: identifying underlying causes of weight gain, combining medication and non-pharmacological strategies, and long-term support
  • Diagnosis and treatment of endocrine-related skin, hair, and nail issues
  • Ongoing care for patients with osteoporosis, pituitary, and adrenal gland disorders
Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.
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€66
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Sergio Correa

General medicineGeriatrics8 years of experience

Dr. Sergio Correa is a licensed general practitioner, aesthetic medicine specialist, and trichologist with experience in emergency care and preventive health. He offers online consultations in English and Spanish, supporting adult patients with a wide range of medical concerns – from acute symptoms to chronic condition management.His areas of focus include:

  • General and urgent care: fever, fatigue, infections, digestive issues, respiratory symptoms, and other common concerns
  • Chronic condition support: hypertension, high cholesterol, diabetes, thyroid issues
  • Aesthetic medicine and dermatology: acne, skin ageing, hyperpigmentation, personalised skincare guidance
  • Trichology: hair loss, scalp conditions, treatment strategies for men and women
  • Preventive care: health check-ups, lifestyle advice, second opinions

Dr. Correa combines medical knowledge with an aesthetic and holistic approach to help patients improve both health and quality of life.

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Antonio Cayatte

General medicine44 years of experience

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic. His clinical background includes: 

  • assessment of sudden or unclear symptoms
  • ongoing care for chronic conditions
  • follow-up after hospital discharge
  • interpretation of test results
  • medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association. Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Dr. Antonio Cayatte provides comprehensive care for a broad spectrum of common health concerns, including:

  • Respiratory & ENT: acute bronchitis, concerns related to pneumonia, sinusitis, tonsillitis, ear infections, sore throat conditions, and allergic rhinitis
  • Eye Health: allergic and infectious conjunctivitis, as well as red or irritated eyes
  • Digestive & Urinary: gastroesophageal reflux disease (GERD), gastritis, urinary tract infections, and cystitis
  • Chronic Conditions: hypertension, elevated cholesterol, and structured weight management planning
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Get Protamine sulfate Leo Pharma Prescription Online

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Frequently Asked Questions

Is a prescription required for Protamine sulfate Leo Pharma?

Protamine sulfate Leo Pharma does not require a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in Protamine sulfate Leo Pharma?

The active ingredient in Protamine sulfate Leo Pharma is protamine. This information helps identify medicines with the same composition but different brand names.

Who manufactures Protamine sulfate Leo Pharma?

Protamine sulfate Leo Pharma is manufactured by Cenexi. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of Protamine sulfate Leo Pharma online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Protamine sulfate Leo Pharma is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy Protamine sulfate Leo Pharma in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy Protamine sulfate Leo Pharma in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to Protamine sulfate Leo Pharma?

Other medicines with the same active substance (protamine) include Siarhan protamini 1%, Acetilcisteine Sandoz, Flumazenil B.braun 0,1 mg/ml roztvur do vstzhikivani. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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