How to use Pegorion
Contents of the leaflet
- Package Leaflet: Information for the User
- Pegorion, 12 g, Powder for Oral Solution
- What is Pegorion and What is it Used For
- Important Information Before Taking Pegorion
- How to Take Pegorion
- Possible Side Effects
- How to Store Pegorion
- Contents of the Package and Other Information
Package Leaflet: Information for the User
Pegorion, 12 g, Powder for Oral Solution
Macrogol
Read the Package Leaflet Carefully Before Taking the Medicinal Product
This medicinal product should always be taken exactly as described in this package leaflet or as directed by your doctor or pharmacist.
- Keep this package leaflet. You may need to read it again.
- If you have any further questions, ask your pharmacist.
- If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. See section 4.
- If after 14 days there is no improvement or you feel worse, you should contact your doctor.
Table of Contents of the Package Leaflet:
- 1. What is Pegorion and What is it Used For
- 2. Important Information Before Taking Pegorion
- 3. How to Take Pegorion
- 4. Possible Side Effects
- 5. How to Store Pegorion
- 6. Contents of the Package and Other Information
1. What is Pegorion and What is it Used For
Pegorion is used to treat constipation and to soften and ease the passage of hard or dry stools (faecal impaction/obstruction). The active substance, macrogol, works by absorbing water, thereby increasing the amount of water in the stools, making them softer and easier to pass. If after 14 days there is no improvement or you feel worse, you should contact your doctor.
2. Important Information Before Taking Pegorion
When Not to Take Pegorion
- if you are allergic to macrogol;
- if you have a bowel obstruction due to a physical or functional disorder of the bowel wall;
- if you have a perforation of the bowel wall;
- if you have severe inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis, toxic megacolon);
- if you have abdominal pain of unknown origin.
Warnings and Precautions
Before taking Pegorion, talk to your doctor or pharmacist.
- if constipation occurs suddenly or gets worse. This could be a sign of bowel obstruction;
- if you experience sudden abdominal pain or rectal bleeding while taking Pegorion for bowel clearance, you should contact your doctor or seek medical attention immediately.
- if you have liver or kidney problems or if you are taking diuretics and experience diarrhoea;
- if constipation is accompanied by pain, fever, or abdominal discomfort.
Remember that treatment of constipation with any medicinal product is only a supplement to a healthy lifestyle and diet, for example:
- increased fluid and fibre intake,
- regular physical activity and bowel habit rehabilitation.
Children and Adolescents
Pegorion powder for oral solution in a 12 g sachet is not intended for use in children under 8 years of age. For children aged 2 to 7 years, 6 g sachets (Pegorion Junior powder for oral solution 6 g) are available. In children, treatment of constipation should not last more than 3 months due to the lack of adequate clinical data beyond 3 months. Therefore, after 3 months of treatment, a full clinical evaluation should be performed to determine the cause of constipation in the patient. In case of diarrhoea, caution should be exercised in patients with a tendency to develop water and electrolyte imbalance.
Pegorion and Other Medicinal Products
Tell your doctor or pharmacist about all medicinal products you are taking or have recently taken, as well as any you plan to take. Pegorion may reduce the absorption of other medicinal products. If you need to thicken fluids to be able to swallow them safely, Pegorion may counteract the thickening effect.
Pregnancy and Breastfeeding
Pegorion can be used during pregnancy and breastfeeding.
Driving and Using Machines
Pegorion has no influence on the ability to drive and use machines.
3. How to Take Pegorion
Take this medicinal product exactly as described in this package leaflet or as directed by your doctor or pharmacist. If you are not sure, talk to your doctor or pharmacist. One sachet of powder (12 g) should be dissolved in 200 ml (a glass) of liquid: water, juice, tea, or coffee. The solution should be prepared just before taking. Treatment of chronic constipation: Adults and children over 8 years: The recommended dose is 1 sachet (12 g) once or twice daily. The dose can be adjusted to produce a comfortable and consistent bowel movement. Pegorion powder for oral solution in a 12 g sachet is not intended for use in children under 8 years of age. For children aged 2 to 7 years, 6 g sachets (Pegorion Junior powder for oral solution 6 g) are available. Treatment with Pegorion usually lasts for up to 2 weeks. If symptoms do not improve after 2 weeks of treatment, you should contact your doctor. Your doctor may also recommend longer treatment. Long-term treatment may be necessary if you are taking medicinal products that cause constipation or have a disease that causes constipation. Softening of dry stools (treatment of faecal impaction/obstruction): Adults and children over 12 years: 5-10 sachets (5-10 x 12 g) per day for 1-3 days. Patients with cardiovascular disorders: The dose should be divided so that no more than two sachets are taken in one hour.
Overdose of Pegorion
Large doses may cause abdominal pain, diarrhoea, and vomiting. In case of overdose, stop taking the medicinal product.
4. Possible Side Effects
Like all medicinal products, Pegorion can cause side effects, although not everybody gets them. Some side effects can be serious. These include:
- Very rare side effects (may affect up to 1 in 10,000 people): Anaphylactic reactions (e.g., anaphylactic shock), angioedema (e.g., sudden swelling of the skin, mucous membranes, or internal organs).
If you experience any of these symptoms or other serious symptoms, you should contact your doctor or the emergency department of your nearest hospital immediately. If you experience an allergic reaction, do not take another dose of this medicinal product and talk to your doctor.
Other Side Effects
Common side effects (may affect up to 1 in 10 people):
- abdominal pain, abdominal distension, nausea, flatulence, or diarrhoea
Uncommon side effects (may affect up to 1 in 100 people):
- vomiting, urgent need to have a bowel movement, faecal incontinence
Very rare side effects (may affect up to 1 in 10,000 people):
- allergic reactions, such as rash, itching
Frequency not known (cannot be estimated from the available data):
- electrolyte and water balance disorders and dehydration, especially in elderly patients
Additional Side Effects in Children and Adolescents
Common side effects (may affect up to 1 in 10 people):
- abdominal pain, diarrhoea (which may cause anal pain)
Uncommon side effects (may affect up to 1 in 100 people):
- vomiting, flatulence, nausea
Frequency not known (cannot be estimated from the available data):
- allergic reactions, such as urticaria, rash, itching
Reporting of Side Effects
If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. You can also report side effects directly to the Department of Monitoring of Adverse Reactions to Medicinal Products, Urząd Rejestracji Produktów Leczniczych, Wyrobów Medycznych i Produktów Biobójczych, Al. Jerozolimskie 181 C, 02-222 Warszawa, Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309, Website: https://smz.ezdrowie.gov.pl. Side effects can also be reported to the marketing authorisation holder. By reporting side effects, you can help provide more information on the safety of this medicinal product.
5. How to Store Pegorion
Keep this medicinal product out of the sight and reach of children. This medicinal product does not require any special storage conditions. Do not use this medicinal product after the expiry date which is stated on the carton and sachet after EXP. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.
6. Contents of the Package and Other Information
What Pegorion Contains
- The active substance is macrogol 4000. One sachet contains 12 grams of macrogol 4000.
- The medicinal product does not contain any other ingredients.
What Pegorion Looks Like and Contents of the Package
White or almost white powder. The package contains 10, 20, or 50 sachets. Not all pack sizes may be marketed.
Marketing Authorisation Holder
Orion Corporation, Orionintie 1, 02200 Espoo, Finland
Manufacturer
Orion Corporation, Orion Pharma, Orionintie 1, 02200 Espoo, Finland. For further information on this medicinal product, please contact the local representative of the marketing authorisation holder: Orion Pharma Poland Sp. z o.o., [email protected]. Date of Last Revision of the Package Leaflet:29.10.2021

- Country of registration
- Dosage formPowder, 12 g
- ATC codeA06AD15
- Active substance
- Prescription requiredNo
- Manufacturer
- ImporterOrion Corporation
- This information is for reference only and does not constitute medical advice. Always consult a doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to PegorionDosage form: Powder, 10 gActive substance: macrogolPrescription not requiredDosage form: Powder, 10 gActive substance: macrogolPrescription requiredDosage form: Concentrate, 52.5 g/100 ml (13.125 g/25 ml)Active substance: macrogolManufacturer: Chephasaar, Chemisch-pharmazeutische Fabrik GmbHPrescription not required
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Frequently Asked Questions
Pegorion does not require a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.
The active ingredient in Pegorion is macrogol. This information helps identify medicines with the same composition but different brand names.
Pegorion is manufactured by Orion Corporation. Pharmacy brands and packaging may differ depending on the distributor.
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Pegorion is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.
You can buy Pegorion in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.
To obtain a prescription, you can use Oladoctor:
Other medicines with the same active substance (macrogol) include Forlax 10 g, Macrogol Aurovitas, Olopeg. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
















