This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use Nifuroksazid Polfarmex

Package Leaflet: Information for the User

NIFUROKSAZYD POLFARMEX, 200 mg, film-coated tablets

Nifuroxazidum

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

This medicine should always be taken exactly as described in this package leaflet for the patient, or as directed by a doctor or pharmacist.

This package leaflet should be kept in case it needs to be read again.
If advice or additional information is needed, a pharmacist should be consulted.
If the patient experiences any side effects, including any possible side effects not listed in the package leaflet, they should inform their doctor or pharmacist. See section 4.
If there is no improvement or the patient feels worse after 3 days, they should contact their doctor.

Package Leaflet Contents

1. What is Nifuroksazyd Polfarmex and what is it used for
2. Important information before taking Nifuroksazyd Polfarmex
3. How to take Nifuroksazyd Polfarmex
4. Possible side effects
5. How to store Nifuroksazyd Polfarmex
6. Package contents and other information

1. What is Nifuroksazyd Polfarmex and what is it used for

Nifuroksazyd Polfarmex is a 5-nitrofuran derivative and an antibacterial agent. It exhibits local action in the intestinal lumen against certain species of bacteria.
Nifuroksazyd Polfarmex does not destroy non-pathogenic bacteria that normally occur in the gastrointestinal tract. It does not cause the development of bacterial strains resistant to its action.
After oral administration, the product is partially absorbed (10-20%) from the gastrointestinal tract and is extensively metabolized, with the main circulating compounds in the blood being metabolites.
Nifuroksazyd Polfarmex is used in acute and chronic bacterial diarrhea in adults and children over 7 years old.

2. Important information before taking Nifuroksazyd Polfarmex

When not to take Nifuroksazyd Polfarmex

If the patient is allergic to nifuroxazide, 5-nitrofuran derivatives, or any of the other ingredients of this medicine (listed in section 6). An allergic reaction may manifest as a rash, swelling of the face, lips, tongue, or difficulty breathing, confusion, pallor, rapid breathing, weakness, and fainting (if such symptoms occur, a doctor should be consulted immediately).
It should not be used in children under 7 years old, as children of this age may have difficulty swallowing the tablet.

Warnings and precautions

If diarrhea persists after 2 or 3 days of treatment or worsens during treatment, a doctor should be consulted immediately.
In the event of an allergic reaction with symptoms such as rash, itching, swelling, confusion, pallor, rapid breathing, weakness, and fainting, the use of Nifuroksazyd Polfarmex should be discontinued.
It is necessary to drink plenty of fluids, sweet or salty, to replenish lost fluids due to diarrhea (average water requirement for an adult is 2 liters).
It is recommended to continue eating during the entire duration of diarrhea:
excluding certain food products - in particular raw vegetables, fruits, green vegetables, spicy dishes, as well as frozen food and cold drinks;
grilled meat and rice are preferred;
alcohol should not be consumed during treatment with nifuroxazide.
As a precautionary measure, Nifuroksazyd Polfarmex should not be administered during pregnancy and breastfeeding.

In the event of severe and prolonged diarrhea, severe vomiting, or loss of appetite, a doctor should be consulted, as intravenous hydration may be necessary.
Before starting treatment with Nifuroksazyd Polfarmex, it should be discussed with a doctor or pharmacist.

Nifuroksazyd Polfarmex and other medicines

The patient should inform their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.
Nifuroksazyd Polfarmex reduces the absorption of many medicines from the gastrointestinal tract. Therefore, during treatment with Nifuroksazyd Polfarmex, other oral medicines should not be taken at the same time.

Taking Nifuroksazyd Polfarmex with food, drink, and alcohol

See "Warnings and precautions" and section 3.
Consuming alcohol during treatment with Nifuroksazyd Polfarmex may cause acute and severe intolerance reactions (so-called disulfiram-like reactions).

Pregnancy and breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult a doctor or pharmacist before taking this medicine. As a precautionary measure, Nifuroksazyd Polfarmex should not be administered during pregnancy and breastfeeding. In women of childbearing age, Nifuroksazyd Polfarmex can be used only if they are using effective contraception.

Driving and operating machinery

Nifuroksazyd Polfarmex does not affect the ability to drive and operate machinery.

Nifuroksazyd Polfarmex contains 3.84 mg of lactose monohydrate in one film-coated tablet

If the patient has previously been diagnosed with intolerance to certain sugars, they should consult a doctor before taking the medicine. The medicine contains 0.00384 g of lactose (0.00192 g of glucose and 0.00192 g of galactose) in one film-coated tablet. This should be taken into account in patients with diabetes.

3. How to take Nifuroksazyd Polfarmex

This medicine should always be taken exactly as described in this package leaflet for the patient, or as directed by a doctor or pharmacist. If there are any doubts, a doctor or pharmacist should be consulted.
The recommended dose is:
Adults:800 mg per day in 2-4 divided doses.
Children over 7 years old:600-800 mg per day in 2-4 divided doses.
Nifuroksazyd Polfarmex should not be taken for more than 3 days without consulting a doctor. If symptoms worsen or do not improve after 3 days, a doctor should be consulted. The medicine should not be taken for more than 7 days.
The medicine is taken orally. The tablets should be swallowed whole, washed down with a sufficient amount of liquid (a glass of water). The tablets should not be chewed or crushed.
Nifuroksazyd Polfarmex should not be taken for more than 3 days without consulting a doctor.
If symptoms worsen or do not improve after 3 days, a doctor should be consulted.
During treatment for diarrhea with Nifuroksazyd Polfarmex, it is necessary to replenish fluids (see "Warnings and precautions" in section 2).

Taking a higher dose of Nifuroksazyd Polfarmex than recommended

In the event of taking a higher dose of the medicine than recommended, a doctor or pharmacist should be consulted immediately. The doctor should be shown the packaging with the tablets.

Missing a dose of Nifuroksazyd Polfarmex

If a dose is missed, it should be taken as soon as possible, unless it is almost time for the next dose.
A double dose should not be taken to make up for a missed dose.

Stopping treatment with Nifuroksazyd Polfarmex

Treatment should not be stopped before 3 days have passed, even if the patient feels better.
If there are any further doubts about taking this medicine, a doctor or pharmacist should be consulted.

4. Possible side effects

Like all medicines, Nifuroksazyd Polfarmex can cause side effects, although not everybody gets them.
A doctor should be consulted immediately if an allergic reaction occurs:

allergic reactions, e.g., skin reactions; rash, urticaria, angioedema (manifested as swelling of the face, lips, tongue, or difficulty breathing);
anaphylactic shock (manifested as confusion, pallor, rapid breathing, weakness, and fainting).

The following side effects may also occur:
rare (less than 1 in 1000 patients):
rash;
skin pustules.
unknown (frequency cannot be estimated from available data):
granulocytopenia (reduced number of a certain type of white blood cell - granulocytes);
nodular prurigo in contact allergy to nifuroxazide;
abdominal pain;
nausea;
worsening of diarrhea.
If mild abdominal pain, nausea, and diarrhea occur, there is no need for special treatment or discontinuation of nifuroxazide. If the symptoms are severe, the medicine should be discontinued. In such cases, nitrofuran derivatives should be avoided in the future.

Reporting side effects

If any side effects occur, including any side effects not listed in the package leaflet, a doctor or pharmacist should be informed. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: (22) 49 21 301
Fax: (22) 49 21 309,
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help gather more information on the safety of the medicine.

5. How to store Nifuroksazyd Polfarmex

The medicine should be stored out of sight and reach of children.
It should be stored at a temperature below 25°C.
The medicine should not be used after the expiration date stated on the packaging and blister after: "EXP". The expiration date refers to the last day of the specified month.
Medicines should not be disposed of via wastewater or household waste. A pharmacist should be asked how to dispose of unused medicines. This will help protect the environment.

6. Package contents and other information

What Nifuroksazyd Polfarmex contains

The active substance of the medicine is nifuroxazide (Nifuroxazidum).
One film-coated tablet contains 200 mg of nifuroxazide.
The other ingredients are: potato starch, povidone K-25, magnesium stearate.
Coating: lactose monohydrate, hypromellose 6cP, titanium dioxide (E 171), macrogol 6000, yellow iron oxide (E 172).

What Nifuroksazyd Polfarmex looks like and what the package contains

Nifuroksazyd Polfarmex - film-coated tablet, yellow, round, biconvex, with a nominal diameter of 10 mm, without spots and damage.
The package contains 20 or 30 film-coated tablets.

Marketing authorization holder and manufacturer

Polfarmex S.A.
ul. Józefów 9
99-300 Kutno
Poland (Poland)
Phone: 24 357 44 44
Fax: 24 357 45 45
e-mail: [email protected]

Date of last revision of the package leaflet:

Country of registration
Poland
Active substance
nifuroxazide
Prescription required
No
Manufacturer
Polfarmex S.A.
Importer
Polfarmex S.A.
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
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Prescription not required
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Dosage form: Tablets, 100 mg
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Alternatives to Nifuroksazid Polfarmex in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Nifuroksazid Polfarmex in Ukraine

NIFUROKSAZID RIHTER

Dosage form: tablets, 100 mg

Active substance: nifuroxazide

Manufacturer: TOV "Gedeon Rihter Pol'sa" (kontrol' akosti, dozvil na vipusk serii; virobnictvo nerozfasovanogo produktu, pervinna upakovka, vtorinna upakovka)

Prescription required

NIFUROKSAZID RIHTER

Dosage form: suspension, 220mg/5ml, 90ml in a bottle

Active substance: nifuroxazide

Manufacturer: Gedeon Rihter Rumunia A.T. (virobnictvo nerozfasovanogo produktu, pervinna upakovka, vtorinna upakovka, kontrol' akosti)

Prescription required

NIFUROKSAZID ALKALOID

Dosage form: suspension, 200mg/5ml; 90ml in a bottle

Active substance: nifuroxazide

Manufacturer: ALKALOID AD Skop'e

Prescription required

NIFUROKSAZID ALKALOID

Dosage form: capsules, 200 mg capsules in blister

Active substance: nifuroxazide

Manufacturer: ALKALOID AD Skop'e

Prescription required

NIFUROKSAZID ALKALOID

Dosage form: capsules, 100 mg capsules in blister

Active substance: nifuroxazide

Manufacturer: ALKALOID AD Skop'e

Prescription required

NIFUROKSAZID-SPERKO

Dosage form: capsules, 200mg

Active substance: nifuroxazide

Manufacturer: Spil'ne ukrains'ko-ispans'ke pidpriemstvo "Sperko Ukraina" (povnij cikl virobnictva, vipusk serii; kontrol' akosti)

Prescription required

Online doctors for Nifuroksazid Polfarmex

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Nifuroksazid Polfarmex – subject to medical assessment and local rules.

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Tomasz Grzelewski

Dermatology20 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

seasonal and perennial allergies
allergic rhinitis and chronic nasal symptoms
asthma and breathing difficulties
food and medication allergies
urticaria, atopic dermatitis and skin reactions
recurrent infections in children
sports-related health questions
general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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follow-up after hospital discharge
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Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

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Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
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Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Chronic pain lasting more than 3 months.
Migraines and recurring headaches.
Neck, back, lower back, and joint pain.
Post-traumatic pain following injury or surgery.
Nerve-related pain, fibromyalgia, and neuralgia.

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Respiratory infections (colds, bronchitis, pneumonia).
High blood pressure and metabolic conditions such as diabetes.
Preventive care and routine health check-ups.

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Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
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Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
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General internal medicine and preventive care:

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Lab test analysis, therapy adjustments, medication management.
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Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

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Mar Tabeshadze

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Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.

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Jonathan Marshall Ben Ami

Family medicine8 years of experience

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Respiratory infections (cold, flu, bronchitis, pneumonia).
ENT conditions such as sinusitis, ear infections, and tonsillitis.
Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
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Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
Acute conditions requiring urgent medical attention.
Headaches, migraines, and minor injuries.
Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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Dmytro Horobets

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Areas of expertise:

Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Karim BenHarbi

General medicine8 years of experience

Dr. Karim Ben Harbi is a licensed general practitioner based in Italy. He provides online consultations for adults and children, combining international clinical experience with evidence-based medicine. His care approach is focused on accurate diagnosis, preventive care, and personalised health guidance.

Dr. Ben Harbi received his medical degree from Sapienza University in Rome. His training included hands-on experience in diverse settings — tropical medicine, rural healthcare, and urban outpatient practice. He also conducted clinical research in microbiology, exploring the role of the gut microbiome in chronic gastrointestinal issues.

You can consult Dr. Ben Harbi for:

General health concerns, prevention, and primary care.
Hypertension, type 1 and type 2 diabetes, metabolic issues.
Cold, cough, flu, respiratory infections, sore throat, fever.
Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
Skin rashes, mild allergic reactions, basic dermatological complaints.
Medication guidance, treatment adjustments, prescription review.
Paediatric concerns — fever, infections, general well-being.
Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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