Nicergolinum
Nicergoline, the active substance of the medicine, affects cerebral and peripheral circulation, reduces vascular resistance, inhibits platelet aggregation, and increases blood flow in blood vessels. Nicergoline stimulates metabolic processes in brain cells, increases oxygen and glucose utilization. Thanks to these properties, it improves impaired brain function due to hypoxia.
Nicergolin is used for mild and moderate dementia.
Nicergolin is indicated for use in adults.
Before starting treatment with Nicergolin, discuss it with your doctor:
If, during treatment with Nicergolin, your blood pressure drops, your doctor will recommend stopping the medicine.
In the case of patients taking nicergoline for a long time, before starting treatment, the doctor will check if the heart, lungs, and kidneys are functioning properly. During treatment, the doctor will pay special attention to any signs potentially related to the occurrence of fibrosis. If necessary, appropriate tests will be performed. If fibrosis occurs, treatment will be discontinued.
During treatment with Nicergolin, symptoms typical of ergot alkaloid poisoning (ergotism) may occur, such as: nausea, vomiting, diarrhea, abdominal pain, numbness and tingling in the fingers and toes, confusion, muscle pain in the limbs, cyanosis (see also "Taking a higher dose of Nicergolin than recommended" in section 3 of the leaflet). You should then immediately consult a doctor.
Tell your doctor about all medicines you are taking, have recently taken, or plan to take.
See section 3.
Do not drink alcohol while taking Nicergolin, as it may enhance the undesirable effects of the medicine on the nervous system.
If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, ask your doctor or pharmacist for advice before taking this medicine.
Nicergolin should not be taken during pregnancy. It is not known whether nicergoline passes into breast milk, so Nicergolin should not be taken during breastfeeding.
Nicergolin may cause drowsiness, fatigue, dizziness, and reduced reaction speed.
Avoid driving and operating machines until you are sure that the medicine does not cause these effects.
1 tablet contains 167.2 mg of lactose (which is 176 mg of lactose monohydrate). If you have been diagnosed with intolerance to some sugars, contact your doctor before taking the medicine.
Always take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor.
Normally, the medicine is taken as described below.
The recommended initial dose is 30 mg to 60 mg of nicergoline per day, which is 3 to 6 tablets per day in 2 or 3 divided doses.
Treatment is continued with the initial dose or the dose is reduced depending on the patient's condition.
The medicine should be taken orally before a meal, and if gastrointestinal disorders occur, during a meal. Swallow the tablet whole with water.
Patient with renal and/or hepatic impairment
In patients with renal impairment (serum creatinine > 2 mg%), the doctor will recommend a dose reduction.
Elderly patients
There is no need to modify the administration and dosage of the medicine in elderly patients.
If you feel that the effect of Nicergolin is too strong or too weak, consult your doctor.
If you have taken more than the recommended dose, consult your doctor immediately.
Overdose symptoms:
Slight decrease in blood pressure, which usually does not require treatment. Nicergoline poisoning, like other ergot alkaloids, manifests as peripheral circulation disorders in the form of decreased blood pressure (dizziness, fainting), skin cooling. There is no specific antidote. Symptomatic treatment should be used. In acute poisoning, gastric lavage and activated charcoal are used.
Do not take a double dose to make up for a forgotten dose.
If you have any further questions about the use of this medicine, ask your doctor or pharmacist.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects(occurring in 1 to 10 in 100 patients): discomfort in the abdominal cavity.
Uncommon side effects(occurring in 1 to 10 in 1,000 patients): excitement, confusion, insomnia, drowsiness, dizziness, headache, hypotension, facial flushing, constipation, diarrhea, nausea, itching, increased uric acid levels in the blood.
Frequency not known(cannot be estimated from the available data): feeling of heat, rash.
During long-term treatment with nicergoline, fibrotic reactions (scarring) of the heart muscle, lungs, peritoneum, and retroperitoneum may occur.
If you experience any side effects, including any not listed in this leaflet, tell your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products:
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: 22 49-21-301
Fax: 22 49-21-309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
By reporting side effects, you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the packaging after EXP.
The expiry date refers to the last day of the month stated.
Store in a temperature below 25°C.
Store in the original packaging to protect from light and moisture.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.
Nicergolin is an oral tablet.
Packaging:
A cardboard box contains 1 glass vial made of orange glass, containing 30 tablets.
Pharmaceutical Cooperative FILOFARM
ul. Pułaskiego 39
85-619 Bydgoszcz
For more detailed information on this medicine, contact the representative of the marketing authorization holder.
Pharmaceutical Cooperative FILOFARM
ul. Pułaskiego 39, 85-619 Bydgoszcz
Phone: 52 342 67 88
Information for the blind and visually impaired: The content of the Nicergolin leaflet is available in the Ulotka Audio system under the national free phone number 800 706 848.
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