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Neurobion Advance

Neurobion Advance

Ask a doctor about a prescription for Neurobion Advance

5.0(15)
Doctor

Giorgi Eremeishvili

Urology21 years of experience

Giorgi Eremeishvili is a top-category urologist, a Candidate of Medical Sciences, and a licensed physician in Spain. He provides expert assistance in the diagnosis and treatment of a wide range of urological conditions in both men and women, employing a comprehensive approach and evidence-based principles.

Key areas of expertise:

  • Erectile dysfunction, decreased libido, premature ejaculation.
  • Male infertility: comprehensive diagnosis and modern treatment methods.
  • Prostate gland diseases: acute and chronic prostatitis, prostatic adenoma (benign prostatic hyperplasia), prostate cancer.
  • Inflammatory diseases of the genitourinary system: acute and chronic cystitis, pyelonephritis, epididymitis, orchitis, urethritis.
  • Sexually transmitted infections (STIs): chlamydia, ureaplasmosis, mycoplasmosis, gardnerellosis, candidiasis, herpetic infections, HPV, CMV, trichomoniasis, and others.
  • Urination disorders: urinary retention, frequent urination, urinary incontinence, overactive bladder, neurogenic bladder.
  • Neoplasms: cysts, tumors of the kidneys, bladder, testicles, prostate gland (including prostate cancer).
  • Surgical interventions: determining indications and selecting optimal minimally invasive methods.

Dr. Eremeishvili applies an integrated approach to each case. This includes thorough preoperative preparation, postoperative observation, and regular dynamic follow-up during the treatment process to achieve the best possible outcomes. All diagnostic and therapeutic recommendations are based on current evidence-based medicine and comply with the recommendations of the European Association of Urology, guaranteeing high-quality and effective care.

If you are seeking qualified assistance in diagnosing or treating urological conditions, book an online consultation with Dr. Giorgi Eremeishvili. Get expert support, accurate diagnosis, and a personalized treatment plan from the comfort of your home.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Neurobion Advance

Package Leaflet: Information for the Patient

Neurobion Advance

100 mg + 50 mg + 1 mg, coated tablets

Thiamine nitrate+ Pyridoxine hydrochloride+ Cyanocobalamin

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

This medicine should always be taken exactly as described in this package leaflet for the patient, or as directed by a doctor, pharmacist, or nurse.

  • This package leaflet should be kept in case it needs to be read again.
  • If advice or additional information is needed, a pharmacist should be consulted.
  • If the patient experiences any side effects, including any side effects not listed in this package leaflet, they should inform their doctor, pharmacist, or nurse. See section 4.
  • If there is no improvement or the patient feels worse after 30 days, they should contact their doctor.

Table of Contents of the Package Leaflet

  • 1. What is Neurobion Advance and what is it used for
  • 2. Important information before taking Neurobion Advance
  • 3. How to take Neurobion Advance
  • 4. Possible side effects
  • 5. How to store Neurobion Advance
  • 6. Contents of the pack and other information

1. What is Neurobion Advance and what is it used for

Neurobion Advance is a medicine containing thiamine (vitamin B1), pyridoxine (vitamin B6), and cyanocobalamin (vitamin B12), intended for use only in adults. It can be taken to prevent a decrease in the level of these vitamins in the body or to treat their deficiency (insufficient amount of these vitamins in the body). A low level of vitamins B1, B6, or B12 may occur when:

  • the patient does not consume sufficient amounts of foods containing these vitamins;
  • the patient's body is unable to absorb these vitamins from food;
  • the patient has undergone stomach or intestinal surgery, which may affect the absorption of nutrients;
  • the patient has certain diseases, such as inflammatory diseases, which may cause an increased consumption of vitamins by the body;
  • the patient has diseases such as kidney disease, which may cause the removal of more vitamins from the body than normal. A low level of vitamin B1, B6, or B12 may occur more frequently in older adults or patients with neurological diseases, diabetes, or gastrointestinal diseases, such as inflammatory bowel disease or celiac disease. Initially, there may be no symptoms of a low level of vitamin B1, B6, or B12, but symptoms such as fatigue or a feeling of numbness and tingling in the hands and feet may occur.

This medicine should only be used when the patient has any of the above-mentioned symptoms or diseases (i.e., diagnosis has been confirmed by a doctor), and their treatment has been recommended by a doctor.

2. Important information before taking Neurobion Advance

When not to take Neurobion Advance:

  • if the patient is allergic to vitamin B1, B6, B12, or any of the other ingredients of this medicine (listed in section 6);
  • if the patient is under 18 years old.

Warnings and precautions

Before taking Neurobion Advance, the patient should discuss it with their doctor, pharmacist, or nurse:

  • if the patient has megaloblastic anemia. Vitamin B12 (cyanocobalamin) may mask the symptoms of megaloblastic anemia due to folate deficiency. Taking Neurobion Advance may mask this condition due to the presence of vitamin B12 (cyanocobalamin), so caution should be exercised to avoid masking the correct diagnosis.

If the patient experiences any new symptoms after taking Neurobion Advance, they should stop taking the product and consult their doctor, pharmacist, or nurse.

Children and adolescents

Neurobion Advance should not be used in children and adolescents under 18 years old due to the high content of vitamins B1, B6, and B12.

Neurobion Advance and other medicines

The patient should tell their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take. Vitamin B6 may increase the severity of side effects and reduce the therapeutic effect of levodopa. Medicines containing substances such as dopamine decarboxylase inhibitors (e.g., medicines used to treat Parkinson's disease) may cause a deficiency of vitamin B6. Pyridoxine antagonists, such as isoniazid, cycloserine, penicillamine, or hydralazine, may reduce the effectiveness of vitamin B6. Long-term use of loop diuretics (medicines that increase urine production and excretion), such as furosemide, may cause accelerated elimination of vitamin B1 and a decrease in its blood level, as well as a decrease in the blood level of vitamin B6.

Taking Neurobion Advance with food, drink, and alcohol

Alcohol impairs the absorption of vitamin B1.

Pregnancy, breastfeeding, and fertility

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before taking this medicine.

Driving and using machines

No effects of Neurobion Advance on the ability to drive or use machines have been observed.

Neurobion Advance contains sodium

The medicine contains less than 1 mmol (23 mg) of sodium per coated tablet, which means the medicine is considered "sodium-free".

3. How to take Neurobion Advance

This medicine should always be taken exactly as described in this package leaflet for the patient, or as directed by a doctor, pharmacist, or nurse. In case of doubt, the patient should consult their doctor, pharmacist, or nurse. The recommended dose for adults is 1 tablet per day. The tablet should be swallowed with a liquid, during or after a meal. If there is no improvement or the patient feels worse after 30 days, they should contact their doctor. This medicine should not be taken for more than 30 days without consulting a doctor. The patient should consult their doctor if they wish to continue treatment.

Use in children and adolescents

Neurobion Advance should not be used in children and adolescents under 18 years old due to the high content of vitamins B1, B6, and B12.

Overdose of Neurobion Advance

In case of accidental overdose of Neurobion Advance, the patient should inform their doctor or pharmacist or contact the nearest hospital emergency department for additional advice. Symptoms of neuropathy may occur when taking more than one tablet per day for six months or longer, such as increased or decreased sensation of pressure, temperature, and pain in the arms, hands, feet, or legs, numbness, tingling, muscle weakness, decreased reflexes, or other neurological symptoms. In such a case, the patient should stop taking the product and consult their doctor, pharmacist, or nurse.

Missed dose of Neurobion Advance

If the patient forgets to take Neurobion Advance, they should take one dose as soon as possible during the next meal on the same day. The patient should not take a double dose to make up for the missed tablet. In case of further doubts about the use of this medicine, the patient should consult their doctor, pharmacist, or nurse.

4. Possible side effects

Like all medicines, Neurobion Advance can cause side effects, although not everybody gets them. The following side effects may occur with an unknown frequency (frequency cannot be estimated from the available data) during treatment with Neurobion Advance:

  • symptoms of allergic reactions, such as sweating, tachycardia (rapid heart rate), and skin reactions with accompanying itching and hives;
  • gastrointestinal disorders, such as nausea, vomiting, diarrhea, and abdominal pain;
  • change in urine color (red discoloration of urine, which may occur in the first hours after taking the tablet and usually disappears shortly after treatment is discontinued).
  • headache.

Reporting side effects

If the patient experiences any side effects, including any side effects not listed in this package leaflet, they should inform their doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181C, 02-222 Warsaw, Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309, Website: https://smz.ezdrowie.gov.pl. Side effects can also be reported to the marketing authorization holder. By reporting side effects, more information can be collected on the safety of the medicine.

5. How to store Neurobion Advance

There are no special precautions for storage. The medicine should be stored out of sight and reach of children. The medicine should not be used after the expiration date stated on the label after EXP. The expiration date refers to the last day of the month stated. Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Contents of the pack and other information

What Neurobion Advance contains

The active substances of the medicine are thiamine nitrate, pyridoxine hydrochloride, and cyanocobalamin. Each coated tablet contains 100 mg of thiamine nitrate, 50 mg of pyridoxine hydrochloride, and 1 mg of cyanocobalamin. The other ingredients are: Tablet core:microcrystalline cellulose, gelatin, sodium croscarmellose, hypromellose, magnesium stearate, colloidal anhydrous silica, sodium carboxymethylcellulose (type A) Clear coating:polyvinyl alcohol, talc, glycerol monocaprylate, sodium lauryl sulfate White coating:hypromellose, polydextrose, titanium dioxide, macrogol Coating:white beeswax, carnauba wax

What Neurobion Advance looks like and contents of the pack

White, round, biconvex coated tablets Blister packs in a cardboard box, available in packs of 30 tablets.

Marketing authorization holder

P&G Health Germany GmbH Sulzbacher Strasse 40 65824 Schwalbach am Taunus Germany For more detailed information on this medicine, the patient should contact the local representative of the marketing authorization holder: Procter & Gamble Health Poland Sp. z o.o. ul. Zabraniecka 20, 03-872 Warsaw tel. 801 25 88 25

Manufacturer

P&G Health Austria GmbH. & Co. OG Hösslgasse 20 9800 Spittal an der Drau Austria

This medicinal product is authorized in the Member States of the European Economic Area under the following names:

Czech Republic Neurobion Hungary Neurobion 100 mg/50 mg/1 mg filmtabletta Poland Neurobion Advance Slovakia Neurobion 100 mg/50 mg/1 mg filmom obalené tablety

Date of last revision of the package leaflet: 12/2023

  • Country of registration
  • Prescription required
    No
  • Manufacturer
  • Importer
    P&G Health Austria GmbH & Co. OG
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Online doctors for Neurobion Advance

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Neurobion Advance – subject to medical assessment and local rules.

5.0(15)
Doctor

Giorgi Eremeishvili

Urology21 years of experience

Giorgi Eremeishvili is a top-category urologist, a Candidate of Medical Sciences, and a licensed physician in Spain. He provides expert assistance in the diagnosis and treatment of a wide range of urological conditions in both men and women, employing a comprehensive approach and evidence-based principles.

Key areas of expertise:

  • Erectile dysfunction, decreased libido, premature ejaculation.
  • Male infertility: comprehensive diagnosis and modern treatment methods.
  • Prostate gland diseases: acute and chronic prostatitis, prostatic adenoma (benign prostatic hyperplasia), prostate cancer.
  • Inflammatory diseases of the genitourinary system: acute and chronic cystitis, pyelonephritis, epididymitis, orchitis, urethritis.
  • Sexually transmitted infections (STIs): chlamydia, ureaplasmosis, mycoplasmosis, gardnerellosis, candidiasis, herpetic infections, HPV, CMV, trichomoniasis, and others.
  • Urination disorders: urinary retention, frequent urination, urinary incontinence, overactive bladder, neurogenic bladder.
  • Neoplasms: cysts, tumors of the kidneys, bladder, testicles, prostate gland (including prostate cancer).
  • Surgical interventions: determining indications and selecting optimal minimally invasive methods.

Dr. Eremeishvili applies an integrated approach to each case. This includes thorough preoperative preparation, postoperative observation, and regular dynamic follow-up during the treatment process to achieve the best possible outcomes. All diagnostic and therapeutic recommendations are based on current evidence-based medicine and comply with the recommendations of the European Association of Urology, guaranteeing high-quality and effective care.

If you are seeking qualified assistance in diagnosing or treating urological conditions, book an online consultation with Dr. Giorgi Eremeishvili. Get expert support, accurate diagnosis, and a personalized treatment plan from the comfort of your home.

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Dr. Sergei Nalkin, PhD, is a neurologist, specialising in sports medicine and rehabilitation. He provides expert care for patients with neurological, musculoskeletal, and post-traumatic conditions, focusing on functional recovery and long-term symptom relief.

Dr. Nalkin offers consultations and treatment for:

  • Neurological disorders including migraines, tension headaches, and peripheral neuropathies.
  • Rehabilitation after stroke, brain injury, and spinal cord trauma.
  • Chronic pain syndromes and musculoskeletal dysfunctions.
  • Sports-related injuries: prevention, treatment, and recovery planning.
  • Coordination and movement disorders affecting mobility and balance.
  • Custom rehabilitation programmes for neurological and orthopedic conditions.

With a personalised, evidence-based approach, Dr. Nalkin helps patients restore physical function, reduce pain, and improve quality of life through targeted therapy and long-term support.

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General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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She treats adults with respiratory illnesses such as pneumonia, COPD and bronchial asthma, as well as cardiovascular conditions including hypertension and ischaemic heart disease. Her practice also covers gastrointestinal complaints and chronic comorbidities that require careful, structured medical supervision.

Dr Boichuk provides care for children from birth, including acute respiratory viral infections, infectious diseases, pneumonia, bronchitis, bronchial obstruction syndromes and allergic reactions. She offers clear, evidence-based guidance to parents and ensures safe follow-up throughout the child’s recovery.

Her work also includes developing personalised immunisation plans and supporting families with long-term preventive care.

Known for her structured clinical approach and clear communication, Dr Liudmyla Boichuk offers patients of all ages comprehensive, reliable and evidence-based medical care.

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Oleksandr Babushkin

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Dr Oleksandr Babushkin is an orthopaedic and trauma specialist providing online consultations for adults with joint, muscle, and spine-related concerns. He helps patients accurately assess symptoms, manage chronic and acute musculoskeletal conditions, and build effective recovery strategies through evidence-based care.

Online consultations include:

  • Evaluation of musculoskeletal symptoms: acute or chronic pain, stiffness, and reduced mobility.
  • Diagnosis and treatment advice for joint pain (knees, hips, shoulders, elbows), back and neck pain.
  • Support for conditions such as osteoarthritis, bursitis, tendinitis, and nerve compression syndromes.
  • Guidance after injuries: strains, sprains, bruises, suspected fractures, and overuse injuries.
  • Recovery support following orthopaedic surgery or trauma.
  • Monitoring treatment progress and adjusting therapy based on your symptoms and test results.

You can book a consultation if you experience:

  • Joint pain, limited mobility, or cracking sounds during movement.
  • Back or neck pain, especially with prolonged sitting or physical activity.
  • Chronic discomfort that affects your daily life or sleep.
  • Need for post-surgical follow-up or rehabilitation planning.

Dr Babushkin combines his expertise in orthopaedics and trauma care with a personalised, structured approach — helping patients regain mobility, reduce pain, and improve quality of life.

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She offers expert care for:

  • Headaches and migraines, including tension-type and cluster headaches.
  • Neck and back pain, both acute and chronic.
  • Chronic pain syndromes – fibromyalgia, neuropathic pain, post-traumatic pain.
  • Mononeuropathies – carpal tunnel syndrome, trigeminal neuralgia, facial nerve palsy.
  • Polyneuropathies – diabetic, toxic, and other types.
  • Multiple sclerosis – diagnosis, monitoring, long-term support.
  • Dizziness and coordination disorders.
  • Sleep disturbances – insomnia, daytime sleepiness, fragmented sleep.
  • Anxiety, depression, and stress-related conditions.

Dr. Agapova helps patients manage complex neurological symptoms like pain, numbness, weakness, poor sleep, and emotional distress. Her consultations focus on accurate diagnosis, clear explanation of findings, and tailored treatment plans.

If you’re struggling with chronic pain, migraines, nerve disorders, or sleep problems, Dr. Agapova offers professional guidance to restore your well-being.

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Allergology7 years of experience

Dr Marta Reguero Capilla is an allergist and immunologist who works with both adults and children. She specialises in the diagnosis, treatment, and ongoing management of allergic and immune-related conditions through online consultations.

In her practice, Dr Reguero Capilla helps patients understand the causes of their symptoms, review test results, and choose appropriate treatment or monitoring strategies. Her consultations are suitable both for first-time assessments and for follow-up care over time.

Patients commonly consult Dr Marta Reguero Capilla for:

  • allergic rhinitis, seasonal allergies, and perennial allergy symptoms;
  • allergic conditions in adults and children;
  • bronchial asthma and allergy-related respiratory symptoms;
  • urticaria (acute and chronic) and angioedema;
  • food allergies and reactions to foods, additives, or medications;
  • atopic dermatitis, allergic rashes, and persistent itching;
  • unexplained or recurrent allergic reactions;
  • interpretation of laboratory tests, allergy testing, and immunology results;
  • immune system concerns, frequent infections, and reduced immune response;
  • ongoing medical follow-up and treatment adjustment.
Dr Reguero Capilla works in a structured and attentive manner, explaining medical decisions clearly and helping patients make informed choices about their own health or their child’s care.

When clinically appropriate, she may provide recommendations for further tests or referrals that patients can use within Spanish medical networks, including Sanitas and DKV, in accordance with the terms and conditions of those services.

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Nikita Savin

Pediatrics4 years of experience

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  • Preventive care and vaccination planning, including catch-up schedules for children.
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  • Diagnosis, treatment planning, and clinical monitoring for paediatric conditions.
  • Nutritional guidance for infants, including the choice of adapted milk formulas tailored to medical needs.
  • Early identification of rare and orphan diseases.
  • Ongoing care for children with chronic or complex health conditions.
By combining paediatrics with a personalised approach, Dr. Savin ensures professional support that addresses both the physical health and overall well-being of children, while guiding parents at every stage of their child’s growth.
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Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
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  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
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She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
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  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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