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Neurobion Advance

Neurobion Advance

Ask a doctor about a prescription for Neurobion Advance

5.0(46)
Doctor

Nuno Tavares Lopes

Family medicine17 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Neurobion Advance

Package Leaflet: Information for the Patient

Neurobion Advance

100 mg + 50 mg + 1 mg, coated tablets

Thiamine nitrate+ Pyridoxine hydrochloride+ Cyanocobalamin

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

This medicine should always be taken exactly as described in this package leaflet for the patient, or as directed by a doctor, pharmacist, or nurse.

  • This package leaflet should be kept in case it needs to be read again.
  • If advice or additional information is needed, a pharmacist should be consulted.
  • If the patient experiences any side effects, including any side effects not listed in this package leaflet, they should inform their doctor, pharmacist, or nurse. See section 4.
  • If there is no improvement or the patient feels worse after 30 days, they should contact their doctor.

Table of Contents of the Package Leaflet

  • 1. What is Neurobion Advance and what is it used for
  • 2. Important information before taking Neurobion Advance
  • 3. How to take Neurobion Advance
  • 4. Possible side effects
  • 5. How to store Neurobion Advance
  • 6. Contents of the pack and other information

1. What is Neurobion Advance and what is it used for

Neurobion Advance is a medicine containing thiamine (vitamin B1), pyridoxine (vitamin B6), and cyanocobalamin (vitamin B12), intended for use only in adults. It can be taken to prevent a decrease in the level of these vitamins in the body or to treat their deficiency (insufficient amount of these vitamins in the body). A low level of vitamins B1, B6, or B12 may occur when:

  • the patient does not consume sufficient amounts of foods containing these vitamins;
  • the patient's body is unable to absorb these vitamins from food;
  • the patient has undergone stomach or intestinal surgery, which may affect the absorption of nutrients;
  • the patient has certain diseases, such as inflammatory diseases, which may cause an increased consumption of vitamins by the body;
  • the patient has diseases such as kidney disease, which may cause the removal of more vitamins from the body than normal. A low level of vitamin B1, B6, or B12 may occur more frequently in older adults or patients with neurological diseases, diabetes, or gastrointestinal diseases, such as inflammatory bowel disease or celiac disease. Initially, there may be no symptoms of a low level of vitamin B1, B6, or B12, but symptoms such as fatigue or a feeling of numbness and tingling in the hands and feet may occur.

This medicine should only be used when the patient has any of the above-mentioned symptoms or diseases (i.e., diagnosis has been confirmed by a doctor), and their treatment has been recommended by a doctor.

2. Important information before taking Neurobion Advance

When not to take Neurobion Advance:

  • if the patient is allergic to vitamin B1, B6, B12, or any of the other ingredients of this medicine (listed in section 6);
  • if the patient is under 18 years old.

Warnings and precautions

Before taking Neurobion Advance, the patient should discuss it with their doctor, pharmacist, or nurse:

  • if the patient has megaloblastic anemia. Vitamin B12 (cyanocobalamin) may mask the symptoms of megaloblastic anemia due to folate deficiency. Taking Neurobion Advance may mask this condition due to the presence of vitamin B12 (cyanocobalamin), so caution should be exercised to avoid masking the correct diagnosis.

If the patient experiences any new symptoms after taking Neurobion Advance, they should stop taking the product and consult their doctor, pharmacist, or nurse.

Children and adolescents

Neurobion Advance should not be used in children and adolescents under 18 years old due to the high content of vitamins B1, B6, and B12.

Neurobion Advance and other medicines

The patient should tell their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take. Vitamin B6 may increase the severity of side effects and reduce the therapeutic effect of levodopa. Medicines containing substances such as dopamine decarboxylase inhibitors (e.g., medicines used to treat Parkinson's disease) may cause a deficiency of vitamin B6. Pyridoxine antagonists, such as isoniazid, cycloserine, penicillamine, or hydralazine, may reduce the effectiveness of vitamin B6. Long-term use of loop diuretics (medicines that increase urine production and excretion), such as furosemide, may cause accelerated elimination of vitamin B1 and a decrease in its blood level, as well as a decrease in the blood level of vitamin B6.

Taking Neurobion Advance with food, drink, and alcohol

Alcohol impairs the absorption of vitamin B1.

Pregnancy, breastfeeding, and fertility

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before taking this medicine.

Driving and using machines

No effects of Neurobion Advance on the ability to drive or use machines have been observed.

Neurobion Advance contains sodium

The medicine contains less than 1 mmol (23 mg) of sodium per coated tablet, which means the medicine is considered "sodium-free".

3. How to take Neurobion Advance

This medicine should always be taken exactly as described in this package leaflet for the patient, or as directed by a doctor, pharmacist, or nurse. In case of doubt, the patient should consult their doctor, pharmacist, or nurse. The recommended dose for adults is 1 tablet per day. The tablet should be swallowed with a liquid, during or after a meal. If there is no improvement or the patient feels worse after 30 days, they should contact their doctor. This medicine should not be taken for more than 30 days without consulting a doctor. The patient should consult their doctor if they wish to continue treatment.

Use in children and adolescents

Neurobion Advance should not be used in children and adolescents under 18 years old due to the high content of vitamins B1, B6, and B12.

Overdose of Neurobion Advance

In case of accidental overdose of Neurobion Advance, the patient should inform their doctor or pharmacist or contact the nearest hospital emergency department for additional advice. Symptoms of neuropathy may occur when taking more than one tablet per day for six months or longer, such as increased or decreased sensation of pressure, temperature, and pain in the arms, hands, feet, or legs, numbness, tingling, muscle weakness, decreased reflexes, or other neurological symptoms. In such a case, the patient should stop taking the product and consult their doctor, pharmacist, or nurse.

Missed dose of Neurobion Advance

If the patient forgets to take Neurobion Advance, they should take one dose as soon as possible during the next meal on the same day. The patient should not take a double dose to make up for the missed tablet. In case of further doubts about the use of this medicine, the patient should consult their doctor, pharmacist, or nurse.

4. Possible side effects

Like all medicines, Neurobion Advance can cause side effects, although not everybody gets them. The following side effects may occur with an unknown frequency (frequency cannot be estimated from the available data) during treatment with Neurobion Advance:

  • symptoms of allergic reactions, such as sweating, tachycardia (rapid heart rate), and skin reactions with accompanying itching and hives;
  • gastrointestinal disorders, such as nausea, vomiting, diarrhea, and abdominal pain;
  • change in urine color (red discoloration of urine, which may occur in the first hours after taking the tablet and usually disappears shortly after treatment is discontinued).
  • headache.

Reporting side effects

If the patient experiences any side effects, including any side effects not listed in this package leaflet, they should inform their doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181C, 02-222 Warsaw, Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309, Website: https://smz.ezdrowie.gov.pl. Side effects can also be reported to the marketing authorization holder. By reporting side effects, more information can be collected on the safety of the medicine.

5. How to store Neurobion Advance

There are no special precautions for storage. The medicine should be stored out of sight and reach of children. The medicine should not be used after the expiration date stated on the label after EXP. The expiration date refers to the last day of the month stated. Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Contents of the pack and other information

What Neurobion Advance contains

The active substances of the medicine are thiamine nitrate, pyridoxine hydrochloride, and cyanocobalamin. Each coated tablet contains 100 mg of thiamine nitrate, 50 mg of pyridoxine hydrochloride, and 1 mg of cyanocobalamin. The other ingredients are: Tablet core:microcrystalline cellulose, gelatin, sodium croscarmellose, hypromellose, magnesium stearate, colloidal anhydrous silica, sodium carboxymethylcellulose (type A) Clear coating:polyvinyl alcohol, talc, glycerol monocaprylate, sodium lauryl sulfate White coating:hypromellose, polydextrose, titanium dioxide, macrogol Coating:white beeswax, carnauba wax

What Neurobion Advance looks like and contents of the pack

White, round, biconvex coated tablets Blister packs in a cardboard box, available in packs of 30 tablets.

Marketing authorization holder

P&G Health Germany GmbH Sulzbacher Strasse 40 65824 Schwalbach am Taunus Germany For more detailed information on this medicine, the patient should contact the local representative of the marketing authorization holder: Procter & Gamble Health Poland Sp. z o.o. ul. Zabraniecka 20, 03-872 Warsaw tel. 801 25 88 25

Manufacturer

P&G Health Austria GmbH. & Co. OG Hösslgasse 20 9800 Spittal an der Drau Austria

This medicinal product is authorized in the Member States of the European Economic Area under the following names:

Czech Republic Neurobion Hungary Neurobion 100 mg/50 mg/1 mg filmtabletta Poland Neurobion Advance Slovakia Neurobion 100 mg/50 mg/1 mg filmom obalené tablety

Date of last revision of the package leaflet: 12/2023

  • Country of registration
  • Prescription required
    No
  • Manufacturer
  • Importer
    P&G Health Austria GmbH & Co. OG
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Online doctors for Neurobion Advance

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Neurobion Advance – subject to medical assessment and local rules.

5.0(46)
Doctor

Nuno Tavares Lopes

Family medicine17 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Duarte Meneses

Family medicine4 years of experience

Dr. Duarte Meneses is a licensed family medicine and general practice doctor based in Portugal, with additional expertise in occupational health. He provides online consultations for adults, offering medical support for both acute symptoms and chronic health conditions.

  • Common symptoms such as fever, sore throat, cough, fatigue, or digestive issues
  • Chronic conditions including hypertension, diabetes, high cholesterol, and thyroid problems
  • Mental health concerns such as stress, sleep issues, anxiety, and burnout
  • Preventive care: health check-ups, lifestyle advice, and follow-up for existing conditions
  • Work-related health questions, sick leave documentation, and medical guidance for returning to work
Dr. Meneses graduated from the University of Beira Interior and has years of experience working with diverse patient populations. He is fluent in Portuguese, English, Spanish, and French.

His approach is friendly, clear, and focused on delivering practical medical advice tailored to each patient’s needs.

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Sergio Correa

General medicine7 years of experience

Dr. Sergio Correa is a licensed general practitioner, aesthetic medicine specialist, and trichologist with experience in emergency care and preventive health. He offers online consultations in English and Spanish, supporting adult patients with a wide range of medical concerns – from acute symptoms to chronic condition management.

His areas of focus include:

  • General and urgent care: fever, fatigue, infections, digestive issues, respiratory symptoms, and other common concerns
  • Chronic condition support: hypertension, high cholesterol, diabetes, thyroid issues
  • Aesthetic medicine and dermatology: acne, skin ageing, hyperpigmentation, personalised skincare guidance
  • Trichology: hair loss, scalp conditions, treatment strategies for men and women
  • Preventive care: health check-ups, lifestyle advice, second opinions

Dr. Correa combines medical knowledge with an aesthetic and holistic approach to help patients improve both health and quality of life.

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Farouk Laafif

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Dr. Farouk Laafif is a psychiatrist providing online consultations for adults and adolescents facing emotional or mental health challenges. His clinical approach integrates psychopharmacology with psychotherapy, with a strong focus on the connection between mental and physical well-being.

He offers compassionate, evidence-based support for individuals dealing with:

  • depression and anxiety disorders
  • bipolar affective disorder
  • schizophrenia and other psychotic conditions
  • psychosomatic symptoms and chronic stress
  • treatment planning and medication adjustment
Dr. Laafif combines scientific expertise with human empathy, helping patients restore emotional balance, improve daily functioning, and regain confidence in their recovery journey.
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Hocine Lokchiri

General medicine20 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Alina Tsurkan

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Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Svetlana Kovalenko

Family medicine14 years of experience

Dr Svetlana Kovalenko is a family medicine doctor with over 14 years of experience and a medical degree from Kharkiv National Medical University. She offers online consultations for adults, supporting patients with both acute and chronic conditions, preventive care, and personalised medical advice.

What patients commonly consult her for:

  • High blood pressure, type 2 diabetes, cholesterol management
  • Cold and flu symptoms: fever, cough, sore throat
  • Fatigue, sleep problems, headaches, general discomfort
  • Ongoing care for chronic conditions and medication review
  • Help interpreting test results and lab reports
  • Preventive check-ups and advice on healthy lifestyle habits

Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

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Iryna Reznychenko

Gynecology25 years of experience

Dr Iryna Reznychenko is an obstetrician-gynaecologist, paediatric gynaecologist, and certified lactation consultant. She provides online consultations for women at all stages of life – from adolescence to menopause. Her work combines medical care for gynaecological conditions with dedicated support for breastfeeding challenges, both physical and emotional.

Areas of expertise:

  • interpretation of test results and personalised treatment planning
  • menstrual irregularities, PCOS, endometriosis
  • abnormal uterine bleeding, endometrial hyperplasia, cervical dysplasia
  • care during perimenopause and menopause, hormonal balance, cancer prevention
  • breastfeeding issues: nipple pain, cracked skin, blocked ducts, low milk supply
  • support during the postpartum and lactation period
Dr Reznychenko offers a clear, attentive and professional approach. Her consultations help prevent minor discomforts from developing into more serious concerns – all in a convenient online format.
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Tomasz Grzelewski

Dermatology20 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Doctor

Lina Travkina

Family medicine12 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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