HISTIGEN 16 mg Tablets

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Doctor
5.0(14)

Sergey Ilyasov

PsychiatryNeurology7 years of experience

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Book a video appointment
€106
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Histigen

Contents of the leaflet

  1. Package Leaflet: Information for the User
  2. Histigen, 8 mg, tablets
  3. Histigen, 16 mg, tablets
    1. Important: Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.
    2. Table of Contents of the Leaflet:
    3. What is Histigen and what is it used for
  4. Important information before taking Histigen
    1. When not to take Histigen
    2. Warnings and precautions
    3. Special warnings
    4. Histigen and other medicines
    5. Pregnancy, breastfeeding, and fertility
    6. Driving and using machines
  5. How to take Histigen
    1. Overdose of Histigen
    2. Missing a dose of Histigen
  6. Possible side effects
    1. Reporting side effects
  7. How to store Histigen
  8. Contents of the pack and other information
    1. What Histigen contains
    2. What Histigen looks like and contents of the pack
    3. Marketing authorization holder and manufacturer
    4. Viatris Healthcare Sp. z o.o.
    5. Date of last revision of the leaflet:

Package Leaflet: Information for the User

Histigen, 8 mg, tablets

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

Histigen, 16 mg, tablets

(Betahistini dihydrochloridum)

Important: Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4.

Table of Contents of the Leaflet:

  • 1. What is Histigen and what is it used for
  • 2. Important information before taking Histigen
  • 3. How to take Histigen
  • 4. Possible side effects
  • 5. How to store Histigen
  • 6. Contents of the pack and other information

1.

What is Histigen and what is it used for

Histigen contains betahistine, which belongs to a group of medicines used to treat vertigo.
This medicine is indicated for the treatment of certain types of vertigo.

2. Important information before taking Histigen

When not to take Histigen

  • if you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6);
  • if your doctor has diagnosed you with a tumor of the adrenal gland, which can cause high blood pressure (pheochromocytoma).

Warnings and precautions

Special warnings

If you have asthma, you should discuss this with your doctor or pharmacist before taking Histigen.
In such cases, patients taking Histigen should be monitored for the risk of bronchospasm.
Patient with a history of peptic ulcer (gastric ulcers) or patients who have had peptic ulcer in the past should be monitored during treatment.
Do not take Histigen for the following types of vertigo:

  • mild positional vertigo,
  • vertigo associated with central nervous system disorders.

Taking the medicine with food may help reduce gastrointestinal upset.
Before taking the medicine, talk to your doctor or pharmacist.

Histigen and other medicines

Tell your doctor or pharmacist about all medicines you are taking, have recently taken, or might take.
In particular, inform your doctor or pharmacist if you are taking any of the following medicines:

  • antihistamines, which may reduce the effect of betahistine. Betahistine may also reduce the effect of antihistamines.
  • monoamine oxidase inhibitors, used to treat Parkinson's disease. They may increase the effect of Histigen.

Pregnancy, breastfeeding, and fertility

Do not take Histigen during pregnancy, unless your doctor has decided that it is necessary.
If you become pregnant during treatment, consult your doctor, as they will assess whether it is necessary to continue treatment.
If you are pregnant, breastfeeding, or think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

Histigen is unlikely to affect your ability to drive or use machines.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

3. How to take Histigen

Always take this medicine exactly as your doctor has told you.
If you are not sure, ask your doctor or pharmacist.
Dosage
The usual dose is 1 to 2 tablets three times a day. Do not take more than 6 tablets per day.
Caution is advised when giving this medicine to elderly patients.
Use in children and adolescents:
It is not recommended to use betahistine in children and adolescents under 18 years of age.
Method of administration
Oral use.
Take the medicine with food to avoid stomach upset.
Swallow the tablet with a glass of water. Do not chew.

Overdose of Histigen

If you have taken too much of this medicine (overdose), contact your doctor or go to the hospital immediately.

Missing a dose of Histigen

If you miss a dose, take the next dose at the scheduled time. Do not take a double dose to make up for the missed dose.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects (occurring in 1 to 10 users):

  • nausea
  • gastrointestinal disorders
  • headache

Frequency not known (frequency cannot be estimated from the available data):

  • severe decrease in platelet count
  • allergic reactions, which may include swelling of the face, lips, tongue, or throat, causing difficulty in breathing (anaphylaxis)
  • mild gastrointestinal upset, such as vomiting, dry mouth, diarrhea, abdominal pain, bloating, and gas. These side effects can be avoided by taking the tablet with food or reducing the dose.
  • skin allergic reactions, in particular anaphylaxis, rash, redness, itching

Reporting side effects

If you experience any side effects, including those not listed in this leaflet, tell your doctor or pharmacist.
Side effects can be reported directly to the Department of Post-Marketing Surveillance of Adverse Reactions to Medicinal Products, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products,
Al. Jerozolimskie 181C,
02-222 Warsaw,
tel.: +48 22 49 21 301,
fax: +48 22 4921 309,
website: https://smz.ezdrowie.gov.pl.
Reporting side effects will help to provide more information on the safety of this medicine.

5. How to store Histigen

Keep the medicine out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the carton after "EXP". The expiry date refers to the last day of that month.
There are no special precautions for storage.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Histigen contains

  • The active substance is betahistine dihydrochloride (Betahistini dihydrochloridum).
  • The other ingredients are: microcrystalline cellulose, mannitol, citric acid monohydrate, colloidal anhydrous silica, talc.

What Histigen looks like and contents of the pack

Histigen 8 mg is a white or almost white, round tablet with a diameter of about 7 mm, with a score line and marked "256" on one side.
Histigen 16 mg is a white or almost white, round, biconvex tablet with a score line and marked "267" on both sides of the score line on one side. The diameter of the tablet is about 8.5 mm.
Pack sizes:
PVC/PVDC-Aluminum blisters in a cardboard box, containing 30, 60, or 100 tablets.
Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder
Viatris Limited
Damastown Industrial Park
Mulhuddart, Dublin 15
DUBLIN
Ireland
Manufacturer
Mylan Laboratories SAS
Route de Belleville
Lieu-dit Maillard
01400 Châtillon-sur-Chalaronne
France
For further information, contact the marketing authorization holder:

Viatris Healthcare Sp. z o.o.

Tel. +48 22 54 66 400

Date of last revision of the leaflet:

Online doctors for Histigen

Discuss questions about Histigen, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(14)

Sergey Ilyasov

PsychiatryNeurology7 years of experience

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Book a video appointment
€106
Doctor
5.0(22)

Taisiia Proida

Psychiatry7 years of experience

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

Book a video appointment
€156
Doctor
5.0(6)

Anastasiia Hladkykh

Psychiatry15 years of experience

Dr Anastasiia Hladkykh is a physician-psychotherapist and psychologist with over 14 years of experience working with individuals struggling with various types of addictions and their families. She provides online consultations for adults, combining medical knowledge with deep psychological support and practical tools.

Key areas of expertise:

  • Addiction treatment: alcohol and drug dependence, gambling addiction, compulsive behaviours, codependent relationships.
  • Support for families of addicted individuals, behavioural correction within the family system, guidance for maintaining remission.
  • Mental health: depression, bipolar disorder, obsessive-compulsive disorder (OCD), anxiety disorders, phobias, PTSD, generalised anxiety, emotional trauma, and the psychological impact of loss or emigration.
  • Psychoeducation: explaining complex mental health concepts in simple language, helping patients and their families understand diagnoses and treatment steps.
Therapeutic approach:
  • Client-centred, straightforward, and empathetic – focused on practical outcomes and emotional stabilisation.
  • Prescribes medications when needed, but always aims to minimise unnecessary pharmaceutical use.
  • Certified in multiple evidence-based methods: CBT, NLP (Master Practitioner), Ericksonian hypnosis, symbol drama, art therapy, and systemic therapy.
  • Each consultation results in a clear, structured plan – patients leave knowing exactly what to do next.
Experience and background:
  • Member of the German association Gesundheitpraktikerin and the NGO “Mit dem Sonne in jedem Herzen.”
  • More than 18 publications in international peer-reviewed journals, translated into several languages.
  • Volunteer work with Ukrainian refugees and military personnel at the University Clinic of Regensburg.
Book a video appointment
€156
Doctor
5.0(1)

Daria Portnova

Psychiatry31 years of experience

Dr Daria Portnova is a psychiatrist and psychotherapist with over 30 years of clinical experience. She works with adults and adolescents aged 14 and over, providing online psychiatric and psychotherapeutic consultations. In her practice, Dr Portnova supports patients facing the onset of mental health conditions, chronic psychiatric disorders, psychotic symptoms, trauma-related states, and complex emotional crises. Her work is structured and safety-focused, with an emphasis on stabilisation, accurate diagnosis, and long-term improvement in quality of life. Patients consult Dr Daria Portnova for the following concerns: 

  • existential crises and complex life situations;
  • loss, grief, and emotional exhaustion;
  • relationship difficulties, separation, and divorce;
  • psychological and psychiatric trauma, including complex PTSD (cPTSD);
  • anxiety disorders: generalised anxiety disorder and panic disorder;
  • social anxiety and social phobia;
  • obsessive-compulsive disorder (OCD);
  • sleep disorders;
  • depressive disorders;
  • bipolar affective disorder;
  • schizoaffective disorder;
  • schizophrenia;
  • personality disorders.

Dr Portnova combines psychiatric assessment with a psychotherapeutic approach. She works with evidence-based methods, including cognitive behavioural therapy (CBT) and third-wave approaches such as ACT, FACT, and CFT. Consultations are focused on clear clinical understanding, practical recommendations, and ongoing support over time.

Book a video appointment
€116
Doctor
5.0(1)

Pedro Alvarez Guerrero

Psychiatry8 years of experience

Dr. Alvarez Guerrero graduated in Medicine from the San Pablo CEU University in Madrid. He subsequently completed his specialization in Psychiatry in the Department of Psychiatry at Hospital Sant Joan de Deu in Manresa (Barcelona), where over the course of four years he acquired solid training in the bio-psycho-social model, developing his expertise across the different areas of mental health.

During his residency, he undertook training placements at Hospital Clínic de Barcelona, where he trained for several months in the psychiatric consultation-liaison unit. He also completed another placement at Hospital de Cruces in Bilbao, in the first-episode psychosis unit.

Throughout his professional career, Dr. Alvarez Guerrero has sought to complement his medical training with psychotherapeutic tools that allow him to address mental health disorders from a comprehensive perspective. For this reason, he specialized in Brief Strategic Psychotherapy through the Spanish Society of Psychosomatic Medicine and Psychotherapy, an approach focused on targeted and effective interventions.

With the aim of deepening his knowledge and promoting the rational use of treatments, he also completed a Master’s Degree in Psychopharmacology at the University of Valencia, which has enabled him to rigorously integrate the most up-to-date scientific evidence into the clinical management of psychopharmacological treatments.

He has also shown a particular interest in the field of legal psychiatry, completing an Official Master’s Degree in Legal, Forensic and Criminological Psychopathology at the Universitat Internacional de Catalunya. This training has allowed him to acquire the necessary competencies for the preparation of psychiatric expert reports in judicial and medico-legal contexts, thereby broadening the scope of his professional activity.

Book a video appointment
€116

Get Histigen Prescription Online

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Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

Is a prescription required for Histigen?

Histigen requires a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in Histigen?

The active ingredient in Histigen is betahistine. This information helps identify medicines with the same composition but different brand names.

Who manufactures Histigen?

Histigen is manufactured by Mylan Laboratories SAS. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of Histigen online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Histigen is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy Histigen in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy Histigen in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to Histigen?

Other medicines with the same active substance (betahistine) include Apobetina, Apobetina, Apobetina. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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