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Furocef

Furocef

Ask a doctor about a prescription for Furocef

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Furocef

Leaflet attached to the packaging: patient information

Furocef, 250 mg, film-coated tablets

Furocef, 500 mg, film-coated tablets

Cefuroxime

Read the leaflet carefully before taking the medicine, as it contains important information for the patient.

  • The leaflet should be kept in case it needs to be read again.
  • In case of any doubts, the patient should consult a doctor or pharmacist.
  • This medicine has been prescribed to a specific person. It should not be given to others. The medicine may harm another person, even if the symptoms of their illness are the same.
  • If the patient experiences any side effects, including any side effects not listed in this leaflet, they should tell their doctor or pharmacist. See section 4.

Table of contents of the leaflet

  • 1. What is Furocef and what is it used for
  • 2. Important information before taking Furocef
  • 3. How to take Furocef
  • 4. Possible side effects
  • 5. How to store Furocef
  • 6. Contents of the packaging and other information

1. What is Furocef and what is it used for

Furocef is an antibiotic used in adults, adolescents, and children with a body weight of over 40 kg.
The medicine works by killing bacteria that cause infections. Furocef belongs to a group of medicines called
cephalosporins.
Furocef is used to treat infections of the:

  • throat,
  • sinuses,
  • middle ear,
  • lungs or chest,
  • urinary tract,
  • skin and soft tissues.

Furocef may also be used:

  • to treat early stages of Lyme disease (borreliosis - an infection transmitted by ticks).

2. Important information before taking Furocef

When not to take Furocef

  • or any of the other ingredients of this medicine (listed in section 6),
  • if the patient has ever had a severe allergic reaction (hypersensitivity) to any other type of beta-lactam antibiotic (penicillins, monobactams, or carbapenems),
  • if the patient has ever had a severe skin rash or skin peeling, blisters, and (or) mouth ulcers after taking cefuroxime or other cephalosporin antibiotics.

If any of the above applies to the patient, they should not takeFurocef without consulting a
doctor.

Warnings and precautions

Before starting to take Furocef, the patient should discuss it with their doctor or pharmacist.
Severe skin reactions, such as:
Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic
symptoms (DRESS), have been reported with cefuroxime. If the patient notices any of the symptoms associated with severe skin reactions described in section 4, they should seek medical advice immediately.
While taking Furocef, the patient should be aware of the following conditions and tell their doctor if they experience any of them: allergic reactions, fungal infections (e.g., thrush), and severe diarrhea (pseudomembranous colitis). This will reduce the risk of complications. See "Conditions to watch out for" in section 4.

Blood tests

Furocef may affect the results of blood sugar tests and a blood test called the Coombs test.
If the patient is to have blood tests, they should tell the person taking the blood samplethat they are taking Furocef.

Furocef and other medicines

The patient should tell their doctor or pharmacist about all medicines they are taking, have recently taken, or might take, including those obtained without a prescription.
The patient should tell their doctor or pharmacistif they are taking:

  • medicines that reduce stomach acid(e.g., antacids used to treat heartburn) may affect the action of Furocef.
  • probenecid.
  • oral anticoagulants (blood thinners).

Furocef with food and drink

Furocef should be taken after a meal. This will help increase the effectiveness of the treatment.

Pregnancy, breastfeeding, and fertility

The patient should inform their doctor before taking Furocef:

  • if they are pregnant, think they may be pregnant, or plan to become pregnant,
  • if they are breastfeeding.

The doctor will assess whether the benefits of taking Furocef during pregnancy and breastfeeding outweigh the risks to the baby.

Driving and using machines

Furocef may cause dizzinessand other side effects that may impair the patient's alertness.
The patient should not drive or operate machineryif they do not feel well.

Furocef contains sodium

The medicine contains less than 1 mmol (23 mg) of sodium per tablet, which means it is considered "sodium-free".

3. How to take Furocef

This medicine should always be taken exactly as advised by the doctor or pharmacist.If the patient is unsure, they should consult their doctor or pharmacist.
Furocef should be taken after a meal. This will help increase the effectiveness of the treatment. The tablets should be swallowed with water.
The tablets should not be chewed, crushed, or divided- this may reduce the effectiveness of the treatment.

Usual dose

Adults, adolescents, and children (≥40 kg)

The usual dose of Furocef is 250 mg to 500 mg twice a day, depending on the severity and type of infection.

Use in children

Furocef 250 mg and 500 mg, film-coated tablets, are not suitable for use in young children with a body weight below 40 kg.
The usual dose of Furocef is 10 mg/kg body weight (not more than 125 mg) to 15 mg/kg body weight (not more than 250 mg) twice a day, depending on:

  • the severity and type of infection.

Depending on the disease and the patient's response to treatment, the initial dose may be changed or more than one treatment cycle may be necessary.

Patients with kidney disease

If the patient has kidney disease, the doctor may change the dose of Furocef.
If this applies to the patient, they should tell their doctor.

Taking more Furocef than prescribed

If the patient takes more Furocef than prescribed, they may experience neurological disorders, including an increased risk of seizures(epileptic fits).
The patient should contact their doctor or emergency services immediately.If possible, they should show the packaging of Furocef.

Missing a dose of Furocef

The patient should not take a double dose to make up for a missed dose.They should take the next dose at the usual time.

Stopping Furocef

The patient should not stop taking Furocef without consulting their doctor. It is important not to
shorten the prescribed treatment period with Furocef.The patient should not stop taking Furocef without their doctor's advice, even if they feel better. Shortening the recommended treatment period may lead to a relapse of the disease.
If the patient has any further doubts about taking this medicine, they should consult their doctor or pharmacist.

4. Possible side effects

Like all medicines, Furocef can cause side effects, although not everybody gets them.

Conditions to watch out for

A small number of people taking Furocef have reported an allergic reaction or potentially severe skin reaction. The symptoms may be:

  • widespread rash, high fever, and swollen lymph nodes (DRESS or hypersensitivity syndrome),
  • chest pain associated with an allergic reaction, which may be a sign of an allergic myocardial infarction (Kounis syndrome),
  • severe allergic reactionwith symptoms such as: raised, itchy rash, swelling, sometimes of the face or mouth, which may make breathing difficult,
  • skin rash, which may develop into blistersand look like small rings(a dark spot in the center surrounded by a lighter border with a dark ring around the edge),
  • widespread rashes with blisters and peeling skin(which may be a sign of Stevens-Johnson syndrome or toxic epidermal necrolysis),
  • fungal infections. Medicines like Furocef can cause an overgrowth of yeast ( Candida) in the body, leading to a fungal infection (e.g., thrush). The risk of this side effect is higher if Furocef is taken for a long time.
  • severe diarrhea(pseudomembranous colitis). Medicines like Furocef can cause inflammation of the colon (large intestine), leading to severe diarrhea, usually with blood and mucus, abdominal pain, and fever.
  • Jarisch-Herxheimer reaction.When taking Furocef to treat Lyme disease (borreliosis), some patients may experience a high fever, chills, muscle and headache, and skin rash. This is known as a Jarisch-Herxheimer reaction. These symptoms usually last from a few hours to a day.

If the patient experiences any of these symptoms, they should contact their doctor or nurse immediately.

Common side effects(may affect up to 1 in 10 people):

  • fungal infections (e.g., thrush)
  • headache
  • dizziness
  • diarrhea
  • nausea
  • stomach pain.

Common side effects that may be seen in blood tests:

  • increased white blood cell count (eosinophilia)
  • increased liver enzyme activity.

Uncommon side effects(may affect up to 1 in 100 people):

  • vomiting
  • skin rashes.

Uncommon side effects that may be seen in blood tests:

  • decreased platelet count (thrombocytopenia)
  • decreased white blood cell count (leukopenia)
  • positive Coombs test result.

Other side effects

Other side effects occur in a very small number of patients, but the exact frequency is unknown:

  • severe diarrhea (pseudomembranous colitis)
  • allergic reactions
  • skin reactions (including severe)
  • high fever
  • yellowing of the whites of the eyes or skin
  • inflammation of the liver.

Side effects that may be seen in blood tests:

  • rapid breakdown of red blood cells (hemolytic anemia).

Reporting side effects

If the patient experiences any side effects, including any side effects not listed in this leaflet, they should tell their doctor or pharmacist. Side effects can be reported directly to the Department of Medicinal Product Monitoring, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C, 02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of this medicine.

5. How to store Furocef

The medicine should be stored out of sight and reach of children.
The medicine should not be taken after the expiry date stated on the packaging after "EXP". The expiry date refers to the last day of the month.
The batch number is stated on the packaging after "Lot".
There are no special precautions for storing the medicine.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines they no longer use. This will help protect the environment.

6. Contents of the packaging and other information

What Furocef contains

  • The active substance of Furocef is cefuroxime. Furocef, 250 mg, film-coated tablets Each film-coated tablet contains 250 mg of cefuroxime, equivalent to 300.715 mg of cefuroxime axetil. Furocef, 500 mg, film-coated tablets Each film-coated tablet contains 500 mg of cefuroxime, equivalent to 601.43 mg of cefuroxime axetil.
  • The other ingredients are: microcrystalline cellulose, sodium croscarmellose, sodium lauryl sulfate, colloidal anhydrous silica, calcium stearate, calcium carbonate, and crospovidone (type A) in the tablet core, and hypromellose 6cp, titanium dioxide (E 171), propylene glycol, and brilliant blue FCF (E 133) in the tablet coating. See section 2 "Furocef contains sodium".

What Furocef looks like and contents of the pack

Furocef 250 mg, film-coated tablets: blue, biconvex, film-coated tablets in the shape of a capsule with the inscription "204" on one side and smooth on the other; dimensions: 15.1 mm x 8.1 mm
Furocef 500 mg, film-coated tablets: blue, biconvex, film-coated tablets in the shape of a capsule with the inscription "203" on one side and smooth on the other; dimensions: 19.1 mm x 9.1 mm
Packaging:10, 12, 14, 15, 16, 20, or 24 film-coated tablets, in a cardboard box.
Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

KRKA, d.d., Novo mesto, Šmarješka cesta 6, 8501 Novo mesto, Slovenia
To obtain more detailed information on the names of medicinal products in other EU member states, the patient should contact the local representative of the marketing authorization holder:
KRKA-POLSKA Sp. z o.o.
ul. Równoległa 5
02-235 Warsaw
Phone: 22 57 37 500
Date of last revision of the leaflet:18.08.2023

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Alternative to Furocef in Spain

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