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Entecavir Sinoptis

Ask a doctor about a prescription for Entecavir Sinoptis

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Doctor

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Entecavir Sinoptis

Package Leaflet: Information for the User

Entecavir Synoptis, 0.5 mg, Film-Coated Tablets

Entecavir Synoptis, 1 mg, Film-Coated Tablets

Entecavir

Read all of this leaflet carefully before taking this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Pack and Other Information

  • 1. What is Entecavir Synoptis and what is it used for
  • 2. Before you take Entecavir Synoptis
  • 3. How to take Entecavir Synoptis
  • 4. Possible side effects
  • 5. How to store Entecavir Synoptis
  • 6. Contents of the pack and other information

1. What is Entecavir Synoptis and what is it used for

Entecavir Synoptis is an antiviral medicine used to treat adults with long-term (chronic) hepatitis B virus (HBV) infection.

HBVcan cause damage to the liver. Entecavir Synoptis reduces the amount of virus in the body and improves liver function.

Entecavir Synoptis is also used to treat chronic HBV infection in children and adolescents from 2 to less than 18 years of age.

Chronic HBV infectioncan cause damage to the liver. Entecavir Synoptis reduces the amount of virus in the body and improves liver function.

2. Before you take Entecavir Synoptis

Do not take Entecavir Synoptis

  • If you are allergic (hypersensitive)to entecavir or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Before taking Entecavir Synoptis, tell your doctor or pharmacist if you have ever had any kidney problems. This is important because Entecavir Synoptis is removed from the body by the kidneys and you may need a lower dose or to take it less often.

  • If you have had any previous liver problems, tell your doctor. This is important because some people taking Entecavir Synoptis have had severe liver problems.

Do not stop taking Entecavir Synoptis without talking to your doctor first

Some people who stop taking Entecavir Synoptis have had severe liver problems. Your doctor will monitor your liver function for several months after you stop taking Entecavir Synoptis.

  • Tell your doctor if you have ever had HIV (human immunodeficiency virus) infection. You should not take Entecavir Synoptis to treat chronic hepatitis B virus infection if you are not also taking medicines to control your HIV infection. Entecavir Synoptis will not control your HIV infection, and you may develop resistance to HIV medicines.

Taking Entecavir Synoptis does not stop you from infecting others with HBV

HBVcan be passed on through sexual contact or body fluids (including blood). You should continue to take precautions to prevent passing HBV to others.

Entecavir Synoptis belongs to a group of medicines that can cause lactic acidosis (a build-up of lactic acid in the blood) and an enlarged liver

Symptoms such as nausea, vomiting, and abdominal pain can indicate the development of lactic acidosis. This rare but serious side effect has sometimes been fatal. Lactic acidosis occurs more often in women, especially those who are overweight. Your doctor will monitor you while you are taking Entecavir Synoptis.

  • If you have been treated for chronic hepatitis B before, tell your doctor.

Children and adolescents

Entecavir Synoptis should not be used in children under 2 years of age or weighing less than 10 kg.

Entecavir Synoptis with other medicines

Tell your doctor or pharmacist about all the medicines you are taking, have recently taken, or might take.

Taking Entecavir Synoptis with food and drink

Entecavir Synoptis can be taken with or without food. If you have taken medicines containing lamivudine in the past, talk to your doctor about the best way to take Entecavir Synoptis.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. It is not known if entecavir is safe to use during pregnancy. Entecavir Synoptis should not be used during pregnancy unless clearly necessary. Women who can become pregnant should use effective contraception while taking Entecavir Synoptis. If you are breastfeeding, tell your doctor. It is not known if entecavir passes into breast milk.

Driving and using machines

Dizziness, fatigue, and somnolence (sleepiness) are common side effects that may affect your ability to drive or use machines. If you are affected, do not drive or use machines.

Entecavir Synoptis contains lactose and maltodextrin

This medicine contains lactose and maltodextrin (glucose). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. How to take Entecavir Synoptis

The dose of Entecavir Synoptis may vary from person to person

Always take Entecavir Synoptis exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.

The recommended dose is:

  • For adults: 0.5 mg or 1 mg once daily (by mouth).
  • The dose depends on:
    • previous treatment for HBV and the medicines used
    • kidney problems; your doctor may prescribe a lower dose or recommend taking it less often
    • liver function

For children and adolescents (from 2 to less than 18 years of age): your doctor will decide the correct dose based on the child's weight.

If you take more Entecavir Synoptis than you should

Contact your doctor or pharmacist immediately.

If you forget to take Entecavir Synoptis

It is important that you do not miss any doses of Entecavir Synoptis. If you miss a dose, take it as soon as you remember, then take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose.

Do not stop taking Entecavir Synoptis without talking to your doctor first

Some people who stop taking Entecavir Synoptis have had severe liver problems. Tell your doctor immediately if you notice any changes in your symptoms after stopping Entecavir Synoptis.

4. Possible side effects

Like all medicines, Entecavir Synoptis can cause side effects, although not everybody gets them.

Adults

Common (affects up to 1 in 10 people):

  • headache, insomnia, fatigue, dizziness, somnolence
  • nausea, vomiting, diarrhea, dyspepsia
  • increased liver enzymes in the blood

Uncommon (affects up to 1 in 100 people):

  • rash
  • hair loss

Rare (affects up to 1 in 1,000 people):

  • severe allergic reactions

Children and adolescents

Side effects in children and adolescents are similar to those in adults and include:

Very common (affects more than 1 in 10 people):

  • low neutrophil count (a type of white blood cell important for fighting infections)

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

5. How to store Entecavir Synoptis

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister, bottle, or carton.

The expiry date refers to the last day of that month.

There are no special storage conditions for this medicine.

After first opening the bottle, the tablets should be used within 30 days.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

6. Contents of the pack and other information

What Entecavir Synoptis contains

  • The active substance is entecavir. Each film-coated tablet contains 0.5 mg or 1 mg of entecavir (as entecavir monohydrate).
  • The other ingredients are: lactose monohydrate, microcrystalline cellulose, crospovidone (type A), hydroxypropylcellulose, magnesium stearate.

Entecavir Synoptis 0.5 mg, film-coated tablets Tablet coating Opadry II OY-LS-28908 (white): titanium dioxide (E 171), lactose monohydrate, hypromellose 15 mPas, macrogol 4000, hypromellose 3 mPas, hypromellose 50 mPas. Entecavir Synoptis, 1 mg, film-coated tablets Tablet coating Opadry II 57U240038 (pink): hypromellose 15 mPas, titanium dioxide (E 171), polydextrose (E 1200), talc, maltodextrin, triglycerides of saturated fatty acids with medium chain length, iron oxide red (E 172), iron oxide yellow (E 172).

What Entecavir Synoptis looks like and contents of the pack

Entecavir Synoptis, 0.5 mg, film-coated tablets White to off-white, triangular tablets with "0.5" engraved on one side, 8.4 mm ± 0.2 mm in size and 3.7 mm ± 0.3 mm in thickness. Entecavir Synoptis, 1 mg, film-coated tablets Pink, triangular tablets with "1" engraved on one side, 10.6 mm ± 0.2 mm in size and 4.5 mm ± 0.3 mm in thickness. Entecavir Synoptis is available in cardboard boxes containing blisters of OPA/Aluminum/PVC/Aluminum or HDPE bottles with a child-resistant closure.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Synoptis Pharma Sp. z o. o. ul. Krakowiaków 65 02-255 Warszawa

Manufacturer

Pharmathen S.A. Dervenakion 6 Pallini Attiki, 15351 Greece Pharmathen International S.A. Industrial Park Sapes Rodopi Prefecture, Block No 5 Rodopi, 69300 Greece Heumann Pharma GmbH & Co. Generica KG Südwestpark 50 90449 Nürnberg Germany

This medicinal product is authorised in the Member States of the European Economic Area under the following names:

Denmark Entecavir Pharmathen United Kingdom Entecavir Germany Entecavir Heumann 0.5 mg & 1 mg Filmtabletten Italy Entecavir Kabi Spain Entecavir Kabi 0.5 mg comprimidos recubiertos con película EFG Entecavir Kabi 1.0 mg comprimidos recubiertos con película EFG Poland Entecavir Synoptis France ENTECAVIR PHARMATHEN 0.5 mg, comprimé pelliculé ENTECAVIR PHARMATHEN 1 mg, comprimé pelliculé

Date of last revision of the leaflet: January 2022

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Alternative to Entecavir Sinoptis in Spain

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Online doctors for Entecavir Sinoptis

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Entecavir Sinoptis – subject to medical assessment and local rules.

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Svetlana Kovalenko

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Dr Svetlana Kovalenko is a family medicine doctor with over 14 years of experience and a medical degree from Kharkiv National Medical University. She offers online consultations for adults, supporting patients with both acute and chronic conditions, preventive care, and personalised medical advice.

What patients commonly consult her for:

  • High blood pressure, type 2 diabetes, cholesterol management
  • Cold and flu symptoms: fever, cough, sore throat
  • Fatigue, sleep problems, headaches, general discomfort
  • Ongoing care for chronic conditions and medication review
  • Help interpreting test results and lab reports
  • Preventive check-ups and advice on healthy lifestyle habits

Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

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Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Areas of expertise:

  • dyslipidaemia and lipid metabolism disorders
  • prevention and management of atherosclerosis
  • blood pressure monitoring and antihypertensive therapy
  • arrhythmias: diagnosis, follow-up, and treatment adjustment
  • cardiovascular care and recovery support after Covid-19
Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.
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She helps with:

  • Viral infections and cold symptoms (flu, sore throat, cough, runny nose)
  • Review and adjustment of antibiotics
  • Skin rashes and allergic reactions
  • Chronic condition flare-ups, high blood pressure, headaches, fatigue
  • Lab and test interpretation
  • Medication review and adaptation to European standards
  • Patient navigation: what tests are needed, which specialists to see, when an in-person visit is required
Dr Minorskaya also specialises in the diagnosis and management of gastrointestinal conditions, including bloating, abdominal pain, chronic nausea, IBS, and SIBO. She supports patients with unexplained physical symptoms that may be linked to somatisation or stress, helping them find relief and improve quality of life.

She offers care for people undergoing GLP-1 therapy (Ozempic, Mounjaro, and others) for weight management. Her support follows Spanish clinical guidelines, from treatment planning and side effect counselling to regular follow-ups and coordination with private or public healthcare providers.

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Dr. Ben Ami offers expert diagnosis, treatment, and follow-up for:

  • Respiratory infections (cold, flu, bronchitis, pneumonia).
  • ENT conditions such as sinusitis, ear infections, and tonsillitis.
  • Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
  • Urinary tract infections and other common infections.
  • Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
  • Acute conditions requiring urgent medical attention.
  • Headaches, migraines, and minor injuries.
  • Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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Yevgen Yakovenko

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Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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His clinical background includes:

  • assessment of sudden or unclear symptoms
  • ongoing care for chronic conditions
  • follow-up after hospital discharge
  • interpretation of test results
  • medical support while abroad
Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

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He specialises in diagnosing and treating pain conditions that affect quality of life, including:

  • Chronic pain lasting more than 3 months.
  • Migraines and recurring headaches.
  • Neck, back, lower back, and joint pain.
  • Post-traumatic pain following injury or surgery.
  • Nerve-related pain, fibromyalgia, and neuralgia.
In addition to pain management, Dr. Popov helps patients with:
  • Respiratory infections (colds, bronchitis, pneumonia).
  • High blood pressure and metabolic conditions such as diabetes.
  • Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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Lina Travkina

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Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Dmytro Horobets

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Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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