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Debretin

Debretin

Ask a doctor about a prescription for Debretin

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Dmytro Horobets

Family medicine6 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Karim BenHarbi

General medicine8 years of experience

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Dr. Ben Harbi received his medical degree from Sapienza University in Rome. His training included hands-on experience in diverse settings — tropical medicine, rural healthcare, and urban outpatient practice. He also conducted clinical research in microbiology, exploring the role of the gut microbiome in chronic gastrointestinal issues.

You can consult Dr. Ben Harbi for:

  • General health concerns, prevention, and primary care.
  • Hypertension, type 1 and type 2 diabetes, metabolic issues.
  • Cold, cough, flu, respiratory infections, sore throat, fever.
  • Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
  • Skin rashes, mild allergic reactions, basic dermatological complaints.
  • Medication guidance, treatment adjustments, prescription review.
  • Paediatric concerns — fever, infections, general well-being.
  • Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Debretin

Package Leaflet: Information for the Patient

Debretin, 100 mg, Film-Coated Tablets

Trimebutine Maleate

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, including any not listed in this leaflet, tell your doctor or pharmacist. See section 4.

Table of Contents of the Leaflet

  • 1. What is Debretin and what is it used for
  • 2. Important information before taking Debretin
  • 3. How to take Debretin
  • 4. Possible side effects
  • 5. How to store Debretin
  • 6. Contents of the pack and other information

1. What is Debretin and what is it used for

Trimebutine stimulates intestinal motility. The action of the medicine depends on the functional state of the gastrointestinal tract. Regulation of peristalsis includes the entire gastrointestinal tract: the tension of the lower esophageal sphincter, the process of gastric emptying, the peristalsis of the small and large intestines. Trimebutine stimulates the muscles of the intestine with reduced function and acts spasmolytically on muscles with increased motor excitability. Maximum blood concentration occurs after 1 to 2 hours. The medicine is excreted mainly with urine.

Indications

Debretin is used to treat:

  • motility disorders of the gastrointestinal tract, referred to as irritable bowel syndrome;
  • functional disorders of the gastrointestinal tract: diarrhea, constipation, abdominal pain, intestinal spasm.

2. Important information before taking Debretin

When not to take Debretin:

Warnings and precautions

Before taking Debretin, discuss it with your doctor or pharmacist.

Debretin and other medicines

Tell your doctor or pharmacist about all the medicines you are taking, or have recently taken, and about any medicines you plan to take. Concomitant administration of trimebutine with zotepine may enhance anticholinergic effects. Synergism of trimebutine action in combination with rizatriptan in the treatment of migraine headaches has been reported.

Debretin with food and drink

See section 3.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. There are no sufficient data to confirm the safety of trimebutine during pregnancy. The medicine should not be given to women in the first trimester of pregnancy. In the second and third trimesters of pregnancy, the medicine can be used only in cases of absolute necessity. During breastfeeding, taking the medicine is not contraindicated.

Driving and using machines

Debretin does not affect the ability to drive and use machines.

3. How to take Debretin

Take this medicine always as directed by your doctor. If you are not sure, ask your doctor or pharmacist. The medicine is intended for use in adults only. Adults: 1 tablet 3 times a day. In exceptional cases, the dose can be increased to 6 tablets a day in divided doses.

Method of administration

Swallow the tablet whole with a glass of water.

Overdose of Debretin

If you have taken more than the recommended dose of the medicine, seek medical advice immediately. In case of overdose, symptomatic treatment is recommended.

Missed dose of Debretin

Do not take a double dose to make up for a forgotten dose. Return to the dosage schedule prescribed by your doctor. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Debretin can cause side effects, although not everybody gets them. Rare (≥1/10 000 to <1>

Reporting of side effects

If you experience any side effects, including any not listed in this leaflet, tell your doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products, Al. Jerozolimskie 181C, 02-222 Warsaw, Tel.: + 48 22 49 21 301, Fax: + 48 22 49 21 309, Website: https://smz.ezdrowie.gov.pl. Side effects can also be reported to the marketing authorization holder. By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Debretin

Keep the medicine out of the sight and reach of children. Store in a temperature below 25 ° C. Store in a dry place, in the original packaging. Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the month. The inscription on the packaging after the abbreviation EXP means the expiry date, and after the abbreviation Lot/LOT means the batch number. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Debretin contains

  • The active substance is trimebutine maleate. Each tablet contains 100 mg of trimebutine maleate.
  • The other ingredients are: core: microcrystalline cellulose, crospovidone, magnesium stearate; coating: hypromellose, microcrystalline cellulose, stearic acid, titanium dioxide (E171).

What Debretin looks like and contents of the pack

Debretin is white, spherical tablets with a dividing line. The pack contains 20, 30, 40, 60 or 100 film-coated tablets. Not all pack sizes may be marketed.

Marketing authorization holder

Zakłady Farmaceutyczne POLPHARMA S.A., ul. Pelplińska 19, 83-200 Starogard Gdański, tel. + 48 22 364 61 01

Manufacturer

Zakłady Farmaceutyczne POLPHARMA S.A., Medana Division in Sieradz, ul. Władysława Łokietka 10, 98-200 Sieradz, Zakłady Farmaceutyczne POLPHARMA S.A., ul. Pelplińska 19, 83-200 Starogard Gdański, Zakłady Farmaceutyczne POLPHARMA S.A., Production Division in Nowa Dęba, ul. Metalowca 2, 39-460 Nowa Dęba

Date of last revision of the leaflet:

Alternatives to Debretin in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Debretin in Ukraine

Dosage form: tablets, 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, tablets 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, tablets 200mg
Active substance: trimebutine
Prescription required
Dosage form: tablets, tablets 100mg
Active substance: trimebutine
Prescription required

Alternative to Debretin in Spain

Dosage form: TABLET, 135 mg
Active substance: mebeverine
Prescription required

Online doctors for Debretin

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Debretin – subject to medical assessment and local rules.

5.0(12)
Doctor

Dmytro Horobets

Family medicine6 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

CameraBook a video appointment
€60
December 2009:00
December 2009:30
December 2709:00
December 2709:30
January 309:00
More times
0.0(0)
Doctor

Karim BenHarbi

General medicine8 years of experience

Dr. Karim Ben Harbi is a licensed general practitioner based in Italy. He provides online consultations for adults and children, combining international clinical experience with evidence-based medicine. His care approach is focused on accurate diagnosis, preventive care, and personalised health guidance.

Dr. Ben Harbi received his medical degree from Sapienza University in Rome. His training included hands-on experience in diverse settings — tropical medicine, rural healthcare, and urban outpatient practice. He also conducted clinical research in microbiology, exploring the role of the gut microbiome in chronic gastrointestinal issues.

You can consult Dr. Ben Harbi for:

  • General health concerns, prevention, and primary care.
  • Hypertension, type 1 and type 2 diabetes, metabolic issues.
  • Cold, cough, flu, respiratory infections, sore throat, fever.
  • Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
  • Skin rashes, mild allergic reactions, basic dermatological complaints.
  • Medication guidance, treatment adjustments, prescription review.
  • Paediatric concerns — fever, infections, general well-being.
  • Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

CameraBook a video appointment
€79
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Dr Habrykevych follows evidence-based medical standards and adapts each consultation to the patient’s individual situation. The online format allows for timely medical support without the need for an in-person visit.
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Her work also includes developing personalised immunisation plans and supporting families with long-term preventive care.

Known for her structured clinical approach and clear communication, Dr Liudmyla Boichuk offers patients of all ages comprehensive, reliable and evidence-based medical care.

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  • Chronic conditions: diabetes, thyroid disorders.
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Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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