This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use Co-bespres

LEAFLET INCLUDED IN THE PACKAGING: INFORMATION FOR THE PATIENT

Co-Bespres, 80 mg + 12.5 mg, film-coated tablets

Co-Bespres, 160 mg + 25 mg, film-coated tablets

Valsartan + Hydrochlorothiazide

You should carefully read the contents of this leaflet before taking the medicine, as it contains important information for the patient.

You should keep this leaflet, so that you can read it again if you need to.
If you have any further questions, you should ask your doctor or pharmacist.
This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
If you experience any side effects, including those not listed in this leaflet, you should tell your doctor or pharmacist. See section 4.

Table of contents of the leaflet

1. What is Co-Bespres and what is it used for
2. Important information before taking Co-Bespres
3. How to take Co-Bespres
4. Possible side effects
5. How to store Co-Bespres
6. Contents of the pack and other information

1. What is Co-Bespres and what is it used for

Co-Bespres film-coated tablets contain two active substances called valsartan and hydrochlorothiazide. Both of these substances help to control high blood pressure (hypertension).

Valsartanbelongs to a group of medicines called “angiotensin II receptor antagonists”, which help to control high blood pressure. Angiotensin II is a substance in the body that causes blood vessels to constrict, thereby increasing blood pressure. Valsartan works by blocking the action of angiotensin II, resulting in the blood vessels relaxing and blood pressure lowering.
Hydrochlorothiazidebelongs to a group of medicines called thiazide diuretics (also known as “water tablets”). Hydrochlorothiazide increases the amount of urine, which also lowers blood pressure.

Co-Bespres is used to treat high blood pressure that is not adequately controlled by a single active substance.

High blood pressure increases the workload of the heart and blood vessels. If left uncontrolled, it can lead to damage to the blood vessels in the brain, heart, and kidneys, which can result in a stroke, heart failure, or kidney failure. High blood pressure also increases the risk of heart attack. Lowering blood pressure to normal levels reduces the risk of such complications.

2. Important information before taking Co-Bespres

When not to take Co-Bespres

if you are allergic to valsartan, hydrochlorothiazide, sulfonamide derivatives (substances with a similar chemical structure to hydrochlorothiazide), or any of the other ingredients of this medicine (listed in section 6).
if you are pregnant more than 3 months (it is also recommended to avoid taking Co-Bespres in early pregnancy - see section 2: Pregnancy and breastfeeding).
if you have severe liver disease, bile duct obstruction (cholestasis), or liver problems (e.g., primary biliary cirrhosis).
if you have severe kidney disease.
if you are unable to urinate (anuria).
if you are undergoing dialysis.
if you have low levels of potassium or sodium in your blood, or high levels of calcium in your blood, despite treatment.
if you have gout.
if you have diabetes or kidney problems and are taking aliskiren, a medicine that lowers blood pressure.

If any of the above conditions apply to you, do not take Co-Bespres and consult your doctor.

Warnings and precautions

Before taking Co-Bespres, you should discuss it with your doctor or pharmacist.

if you are taking potassium-sparing medicines, potassium supplements, or salt substitutes containing potassium, or other medicines that increase potassium levels in your blood, such as heparin. Your doctor may need to monitor your potassium levels.
if you have low potassium levels in your blood.
if you have diarrhea or severe vomiting.
if you are taking high doses of diuretics (water tablets).
if you have severe heart disease.
if you have heart failure or have had a heart attack. You should strictly follow your doctor's recommendations for starting treatment - kidney function monitoring may also be necessary.
if you have narrowing of the renal arteries.
if you have had a kidney transplant.
if you have hyperaldosteronism - a condition where the adrenal glands produce too much of a hormone called aldosterone. In this case, Co-Bespres is not recommended.
if you have liver or kidney disease.
if you have ever had an allergic reaction, such as angioedema (swelling of the face, lips, tongue, or throat), after taking another medicine (including ACE inhibitors). You should inform your doctor if this has happened. If such symptoms occur while taking Co-Bespres, you should stop taking it immediately and never take it again. See section 4 “Possible side effects”.
if you have a fever, rash, and joint pain, which may be symptoms of systemic lupus erythematosus (SLE, an autoimmune disease).
if you have diabetes, have had gout, have high cholesterol or triglyceride levels in your blood.
if you have had allergic reactions to other blood pressure-lowering medicines of this group (angiotensin II receptor antagonists) or if you are allergic or have asthma.
if you have impaired vision or eye pain. These may be symptoms of fluid accumulation in the vascular layer surrounding the eye (excessive fluid accumulation between the choroid and sclera) or increased eye pressure, which can occur within a few hours to a few weeks after starting Co-Bespres. If left untreated, they can lead to complete loss of vision. In patients allergic to penicillin or sulfonamides, the risk of such complications is higher.

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Country of registration
Poland
Active substance
valsartan and diuretics
Prescription required
Yes
Manufacturer
Pharmachemie B.V. Teva Czech Industries s.r.o. Teva Operations Poland Sp. z o.o. Teva Pharmaceutical Works Private Limited Company
Importer
Pharmachemie B.V. Teva Czech Industries s.r.o. Teva Operations Poland Sp. z o.o. Teva Pharmaceutical Works Private Limited Company
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
Alternatives to Co-bespres
Aurovalsart Hct
Dosage form: Tablets, 80 mg + 12.5 mg
Active substance: valsartan and diuretics
Manufacturer: APL Swift Services (Malta) Ltd.
Prescription required
Aurovalsart Hct
Dosage form: Tablets, 160 mg + 12.5 mg
Active substance: valsartan and diuretics
Manufacturer: APL Swift Services (Malta) Ltd.
Prescription required
Aurovalsart Hct
Dosage form: Tablets, 160 mg + 25 mg
Active substance: valsartan and diuretics
Manufacturer: APL Swift Services (Malta) Ltd.
Prescription required

Alternatives to Co-bespres in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Co-bespres in Spain

VALSARTAN/HYDROCHLOROTHIAZIDE STADA 160mg/25mg FILM-COATED TABLETS

Dosage form: TABLET, 160 mg / 25 mg

Active substance: valsartan and diuretics

Manufacturer: Laboratorio Stada S.L.

Prescription required

VALSARTAN HYDROCHLOROTHIAZIDE COMBIX 80 mg/12.5 mg FILM-COATED TABLETS

Dosage form: TABLET, 80 mg Valsartan; 12.5 mg Hydrochlorothiazide

Active substance: valsartan and diuretics

Manufacturer: Laboratorios Combix S.L.U.

Prescription required

VALSARTAN HYDROCHLOROTHIAZIDE COMBIX 160 mg/25 mg FILM-COATED TABLETS

Dosage form: TABLET, 160 mg Valsartan; 25 mg Hydrochlorothiazide

Active substance: valsartan and diuretics

Manufacturer: Laboratorios Combix S.L.U.

Prescription required

VALSARTAN HYDROCHLOROTHIAZIDE COMBIX 160 mg/12.5 mg FILM-COATED TABLETS

Dosage form: TABLET, 160 mg Valsartan; 12.5 mg Hydrochlorothiazide

Active substance: valsartan and diuretics

Manufacturer: Laboratorios Combix S.L.U.

Prescription required

VALOMINDO 80 mg / 1.5 mg MODIFIED-RELEASE TABLETS

Dosage form: MODIFIED-RELEASE TABLET, 80 mg/1.5 mg

Active substance: valsartan and diuretics

Manufacturer: Krka D.D. Novo Mesto

Prescription required

VALOMINDO 160 mg/1.5 mg MODIFIED-RELEASE TABLETS

Dosage form: MODIFIED-RELEASE TABLET, 160 mg/1.5 mg

Active substance: valsartan and diuretics

Manufacturer: Krka D.D. Novo Mesto

Prescription required

Alternative to Co-bespres in Ukraine

DIOKOR 80

Dosage form: tablets, 80 mg/12.5 mg

Active substance: valsartan and diuretics

Manufacturer: TOV "Farma Start

Prescription required

DIOKOR 160

Dosage form: tablets, 160 mg/12.5 mg

Active substance: valsartan and diuretics

Manufacturer: TOV "Farma Start

Prescription required

VANATEKS KOMBI

Dosage form: tablets, 80 mg/12.5 mg

Active substance: valsartan and diuretics

Manufacturer: Farmacevticnij Zavod "POL'FARMA" S. A.

Prescription required

VANATEKS KOMBI

Dosage form: tablets, 160 mg/25 mg

Active substance: valsartan and diuretics

Manufacturer: Farmacevticnij Zavod "POL'FARMA" S. A.

Prescription required

VANATEKS KOMBI

Dosage form: tablets, 160mg/12.5mg

Active substance: valsartan and diuretics

Manufacturer: Farmacevticnij Zavod "POL'FARMA" S. A.

Prescription required

VAL'SARIA N

Dosage form: tablets, 80 mg/12.5 mg

Active substance: valsartan and diuretics

Manufacturer: Novartis Farma S.p.A.

Prescription required

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