Background pattern

Candepres Hct

About the medicine

How to use Candepres Hct

Leaflet attached to the packaging: patient information

Candepres HCT, 32 mg + 12.5 mg, tablets

Candepres HCT, 32 mg + 25 mg, tablets

Candesartan cilexetil + Hydrochlorothiazide

Read the leaflet carefully before taking the medicine, as it contains important information for the patient.

Keep this leaflet, so you can read it again if you need to.
In case of any doubts, consult a doctor or pharmacist.
This medicine has been prescribed to a specific person. Do not pass it on to others.
The medicine may harm another person, even if their symptoms are the same.
If the patient experiences any side effects, including those not listed in this leaflet, they should tell their doctor or pharmacist. See section 4.

Table of contents of the leaflet:

  • 1. What is Candepres HCT and what is it used for
  • 2. Important information before taking Candepres HCT
  • 3. How to take Candepres HCT
  • 4. Possible side effects
  • 5. How to store Candepres HCT
  • 6. Contents of the packaging and other information

1. What is Candepres HCT and what is it used for

The name of the medicine is Candepres HCT. It is used in adults to treat high blood pressure (hypertension). The medicine contains two active substances: candesartan cilexetil and hydrochlorothiazide, which together lower blood pressure.
Candesartan cilexetil belongs to a group of medicines called angiotensin II receptor antagonists. It causes a decrease in blood vessel tension and their expansion, which helps to lower blood pressure.
Hydrochlorothiazide belongs to a group of diuretic medicines. It helps to remove water and salt (such as sodium) from the body with urine, which helps to lower blood pressure.
A doctor may prescribe Candepres HCT if blood pressure is not properly controlled while taking only candesartan cilexetil or only hydrochlorothiazide (monotherapy).

2. Important information before taking Candepres HCT

When not to take Candepres HCT

if the patient is allergicto candesartan cilexetil or hydrochlorothiazide or to any of the other ingredients of this medicine (listed in section 6);
if the patient is allergic to sulfonamide medicines. In case of doubt, consult a doctor;
if the patient has severe liver diseaseor bile duct narrowing(difficulty in draining bile from the gallbladder);
if the patient has severe kidney problems;
after the 3rd month of pregnancy(it is also recommended to avoid taking Candepres HCT in early pregnancy - see below the section on pregnancy);
if the patient has ever been diagnosed with gout;
if the patient has persistent low potassium levelsin the blood;
if the patient has persistent high calcium levelsin the blood;
if the patient has diabetesor has kidney problemsand is taking a blood pressure-lowering medicine containing aliskiren.
If the patient is unsure whether any of the above applies to them, they should consult a doctor or pharmacist before taking Candepres HCT.

Warnings and precautions

Before starting treatment with Candepres HCT, the patient should discuss it with their doctor or pharmacist if:

the patient has heart, liver, or kidney problems;
the patient has recently undergone a kidney transplant;
the patient currently has or has recently had severe vomitingor has diarrhea;
the patient has been diagnosed with adrenal gland disease(called Conn's syndrome or primary hyperaldosteronism);
the patient has diabetes;
the patient has been diagnosed with a disease called systemic lupus erythematosus(SLE);
the patient has low blood pressure;
the patient has had a strokein the past;
the patient has had an allergyor asthmain the past;
the patient has had breathing problemsor lung problems(including pneumonia or fluid accumulation in the lungs) after taking hydrochlorothiazide. If the patient experiences severe shortness of breath or difficulty breathing after taking Candepres HCT, they should seek medical help immediately.
the patient is taking any of the following medicines used to treat high blood pressure:

  • ACE inhibitor(such as enalapril, lisinopril, ramipril), especially if the patient has diabetic kidney disease
  • aliskirenif the patient has had malignant skin cancerin the past or if an unexpected skin changeoccurs during treatment. Treatment with hydrochlorothiazide, especially in high doses and for a long time, may increase the risk of certain types of skin cancer and lip cancer (non-melanoma skin cancer). When taking Candepres HCT, the patient should protect their skin from sunlight and UV radiation; if the patient experiences vision loss or eye pain. These may be symptoms of fluid accumulation in the vascular layer surrounding the eye (excessive fluid accumulation between the choroid and sclera) or increased pressure inside the eye - they can occur within a few hours to weeks after taking Candepres HCT and, if left untreated, can lead to permanent vision loss. The risk of these disorders may be higher in patients who have previously been allergic to penicillin or sulfonamides; the patient is pregnant or plans to become pregnant.It is not recommended to take Candepres HCT in early pregnancy and it should not be taken after the 3rd month of pregnancy, as it may harm the fetus (see also the section on pregnancy).

The doctor may recommend regular checks of kidney function, blood pressure, and electrolyte levels (such as potassium) in the blood. See also the information in the section "When not to take Candepres HCT".
If the patient has any of the above conditions, the doctor may prescribe more frequent check-ups and perform certain tests.
If the patient is to undergo surgery, they should inform their doctor or dentist that they are taking Candepres HCT, as its combination with certain medicines used during general anesthesia may cause excessive lowering of blood pressure.
Candepres HCT may increase the sensitivity of the skin to sunlight.

Children and adolescents

Candepres HCT should not be used in children and adolescents (under 18 years of age) due to lack of experience in this age group.
If the patient is an athlete and is to undergo a doping test, they should inform their doctor about taking Candepres HCT, as one of its active substances may cause a positive test result.

Candepres HCT and other medicines

Tell your doctor or pharmacist about all medicines you are currently taking or have recently taken, as well as any medicines you plan to take.

Candepres HCT may affect the way some medicines work, and other medicines may affect the way Candepres HCT works. If the patient is taking certain medicines, their doctor may need to perform blood tests from time to time.
In particular, tell your doctor or pharmacist if you are taking any of the following medicines, as your doctor may need to change the dose or recommend other precautions:
ACE inhibitoror aliskiren(see also the information in the section "When not to take Candepres HCT" and "Warnings and precautions");
other blood pressure-lowering medicines, including beta-blockers, aliskiren-containing medicines, diazoxide, and ACE inhibitors, such as enalapril, captopril, lisinopril, or ramipril;
medicines that regulate heart rhythm (anti-arrhythmic medicines), such as digoxin and beta-blockers;
non-steroidal anti-inflammatory medicines (NSAIDs), such as ibuprofen, naproxen, diclofenac, celecoxib, or etoricoxib (medicines used to treat pain and inflammation);
aspirin (in doses greater than 3 g per day), a medicine used to treat pain and inflammation;
potassium supplements or salt substitutes containing potassium (medicines that increase potassium levels in the blood);
heparin (a blood thinner);
diuretic medicines;
lithium (a medicine used to treat mental disorders);
medicines whose effects may be influenced by potassium levels in the blood, such as certain antipsychotic medicines;
medicines used to lower cholesterol levels, such as colestyramine or colestipol (resin medicines that lower fat levels);
calcium or vitamin D supplements;
anticholinergic medicines, such as atropine and bipiperidine;
amantadine (a medicine used to treat Parkinson's disease or severe viral infections);
barbiturates (a group of sedative medicines, also used to treat epilepsy);
medicines used to treat cancer;
corticosteroids, such as prednisolone;
adrenocorticotropic hormone (ACTH);
antidiabetic medicines (in tablet or insulin form);
laxatives;
amphotericin (a medicine used to treat fungal infections);
carbenoxolone (a medicine used to treat esophageal or stomach disease);
penicillin or cotrimoxazole, also known as trimethoprim with sulfamethoxazole (antibiotics);
cyclosporine, a medicine used to prevent organ rejection;
other medicines that may enhance the blood pressure-lowering effect, such as baclofen (a muscle relaxant), amifostine (used to treat cancer), and certain antipsychotic medicines.

Candepres HCT with food, drink, and alcohol

Candepres HCT can be taken with or without food.
If the patient is taking Candepres HCT, they should consult their doctor before consuming alcohol. Alcohol may cause dizziness or fainting.

Pregnancy and breastfeeding

Pregnancy

If the patient suspects that they are pregnant (or may have become pregnant), they must inform

their doctor.The doctor will usually advise the patient to stop taking Candepres HCT before becoming pregnant or as soon as pregnancy is confirmed and recommend taking another medicine instead. It is not recommended to take Candepres HCT in early pregnancy and it should not be taken after the 3rd month of pregnancy, as it may harm the fetus.
Breastfeeding
If the patient is breastfeeding or plans to breastfeed, they should inform their doctor. Candepres HCT is not recommended during breastfeeding, so doctors may recommend alternative treatment for patients who want to breastfeed (especially newborns or premature babies).

Driving and using machines

Some patients taking Candepres HCT may experience drowsiness or dizziness. In such cases, they should not drive vehicles, use any tools, or operate any machines.

Candepres HCT contains lactose

If the patient has been diagnosed with intolerance to some sugars, they should contact their doctor before taking this medicine.

Candepres HCT contains sodium

The medicine contains less than 1 mmol (23 mg) of sodium per tablet, which means it is considered "sodium-free".

3. How to take Candepres HCT

This medicine should always be taken as directed by the doctor. In case of doubt, consult a doctor or pharmacist. It is important to take Candepres HCT every day.
The recommended dose of Candepres HCT is one tablet once a day.
The tablet should be swallowed with water.
Try to take the medicine at the same time every day. This makes it easier to remember to take the medicine.

Taking a higher dose of Candepres HCT than recommended

In case of taking a larger amount of Candepres HCT than recommended, contact a doctor or pharmacist immediately.

Missing a dose of Candepres HCT

Do not take a double dose to make up for a missed dose. Take the next tablet at the usual time.

Stopping treatment with Candepres HCT

If the patient stops taking Candepres HCT, their blood pressure may rise again.
Therefore, do not stop taking the medicine without consulting a doctor.
In case of any further doubts about taking this medicine, consult a doctor or pharmacist.

4. Possible side effects

Like all medicines, Candepres HCT can cause side effects, although not everybody gets them.
It is important for the patient to know that these side effects are possible. Some of them may be caused by candesartan cilexetil, and some by hydrochlorothiazide.

If any of the following allergic reactions occur, stop taking Candepres HCT and seek medical help immediately:

difficulty breathing with swelling of the face, lips, tongue, and (or) throat, with or without such swelling;
swelling of the face, lips, tongue, and (or) throat, which may cause difficulty swallowing;
severe skin itching (with hives).
Also, stop the medicine and seek medical help immediately if the patient experiences
acute respiratory failure (symptoms include severe shortness of breath, fever, weakness, and confusion).
This side effect is very rare (may occur less often than in 1 in 10,000 people).
Candepres HCT may cause a decrease in the number of white blood cells. This may lead to a weakened immune system and an increased risk of infection, as well as fatigue, infection, or fever. In such cases, consult a doctor. The doctor may recommend blood tests to check if Candepres HCT has caused changes in blood composition (agranulocytosis).
Other possible side effects:
Common(may occur in less than 1 in 10 people)
Changes in blood test results:

  • decreased sodium levels in the blood. If this is significant, the patient may experience weakness, lack of energy, or muscle cramps.
  • increased or decreased potassium levels in the blood, especially in patients with kidney problems or heart failure. If these disorders are significant, the patient may experience fatigue, weakness, irregular heartbeat, or tingling.
  • increased cholesterol, sugar, or uric acid levels in the blood. Presence of sugar in the urine. Feeling of dizziness or weakness. Headache. Respiratory tract infection.

Uncommon(may occur in less than 1 in 100 people)
Low blood pressure, which may cause dizziness or fainting.
Lack of appetite, diarrhea, constipation, stomach upset.
Skin rash, hives, sun-induced skin rash.
Rare(may occur in less than 1 in 1,000 people)
Jaundice (yellowing of the skin or whites of the eyes). In such cases, consult a doctor immediately.
Affecting kidney function, especially in patients with kidney problems or heart failure.
Sleep disorders, depression, restlessness.
Tingling or numbness in the hands or feet.
Temporary blurred vision.
Heart rhythm disorders.
Breathing difficulties (including pneumonia or fluid accumulation in the lungs).
High fever (fever).
Pancreatitis, which causes moderate or severe abdominal pain.
Muscle cramps.
Blood vessel damage, which causes red or purple spots on the skin.
Decreased number of red or white blood cells or platelets, with possible fatigue, infection, fever, or easy bruising.
Severe, rapidly developing rash with blistering or peeling of the skin, as well as possible blistering in the mouth.
Very rare(may occur in less than 1 in 10,000 people)
Swelling of the face, lips, tongue, and (or) throat.
Itching.
Back pain, joint pain, and muscle pain.
Changes in liver function, including hepatitis. Possible symptoms include fatigue, yellowing of the skin and whites of the eyes, and flu-like symptoms.
Cough.
Nausea.
Frequency not known(cannot be estimated from available data)
Sudden short-sightedness.
Vision loss or eye pain due to increased pressure (possible symptoms of fluid accumulation in the vascular layer surrounding the eye - excessive fluid accumulation between the choroid and sclera - or acute angle-closure glaucoma).
Systemic lupus erythematosus (an allergic disorder that causes fever, joint pain, rash, e.g., redness, blistering, peeling of the skin, and lump formation).
Malignant skin tumors and lip tumors (non-melanoma skin cancer).

Reporting side effects

If side effects occur, including those not listed in this leaflet, tell your doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products:
Al. Jerozolimskie 181C, 02-222 Warsaw
tel.: +48 22 49 21 301, fax: +48 22 49 21 309, website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of the medicine.

5. How to store Candepres HCT

Keep the medicine out of sight and reach of children.
Do not use this medicine after the expiry date stated on the carton and blister after EXP. The expiry date refers to the last day of the month.
Store in the original packaging to protect from moisture.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Contents of the packaging and other information

What Candepres HCT contains

Tablets 32 mg + 12.5 mg

  • Active substancesare candesartan cilexetil and hydrochlorothiazide. Each tablet contains 32 mg of candesartan cilexetil and 12.5 mg of hydrochlorothiazide.
  • Other ingredients are: lactose monohydrate, yellow iron oxide (E172), red iron oxide (E172), black iron oxide (E172), cornstarch, povidone K30, carrageenan, sodium croscarmellose, and magnesium stearate.

Tablets 32 mg + 25 mg

  • Active substancesare candesartan cilexetil and hydrochlorothiazide. Each tablet contains 32 mg of candesartan cilexetil and 25 mg of hydrochlorothiazide.
  • Other ingredients are: lactose monohydrate, red iron oxide (E172), black iron oxide (E172), titanium dioxide (E171), cornstarch, povidone K30, carrageenan, sodium croscarmellose, and magnesium stearate.

What Candepres HCT looks like and contents of the pack

Tablets 32 mg + 12.5 mg
Light brown, speckled, oblong, biconvex tablet with the symbol ‘32’ embossed on one side and a score line on both sides.
Tablets 32 mg + 25 mg
Brown-red, speckled, oblong, biconvex tablet with the symbol ‘H 32’ embossed on one side and a score line on both sides.
The score line on the tablet is only to facilitate breaking and does not allow for division into equal doses.
Aluminum/Aluminum blister pack with a desiccant, in a cardboard box.
Pack sizes: 28, 30, 56, 60, or 90 tablets.

Marketing authorization holder and manufacturer

Marketing authorization holder
Sandoz GmbH
Biochemiestrasse 10
6250 Kundl, Austria
Manufacturer
Lek Pharmaceuticals d.d.
Verovškova 57
1526 Ljubljana, Slovenia
Salutas Pharma GmbH
Otto-von-Guericke Allee 1,
39179 Barleben, Germany
Lek Pharmaceuticals d.d.
Trimlini 2D
9220 Lendava, Slovenia
Lek S.A.
ul. Domaniewska 50 C
02-672 Warsaw

To obtain more detailed information about the medicine and its names in the Member States of the European Economic Area, contact:

Sandoz Polska Sp. z o.o.
ul. Domaniewska 50 C
02-672 Warsaw
tel. 22 209 70 00
Date of last revision of the leaflet:02/2022
Sandoz logo

  • Country of registration
  • Active substance
  • Prescription required
    Yes
  • Importer
    Lek Pharmaceuticals d.d. Lek Pharmaceuticals d.d. LEK S.A. Salutas Pharma GmbH

Talk to a doctor online

Need help understanding this medicine or your symptoms? Online doctors can answer your questions and offer guidance.

5.0(21)
Doctor

Ekaterina Agapova

Neurology8 years of experience

Dr. Ekaterina Agapova is a neurologist specialising in the diagnosis and treatment of neurological conditions and chronic pain. She provides online consultations for adults, combining evidence-based medicine with a personalised approach.

She offers expert care for:

  • Headaches and migraines, including tension-type and cluster headaches.
  • Neck and back pain, both acute and chronic.
  • Chronic pain syndromes – fibromyalgia, neuropathic pain, post-traumatic pain.
  • Mononeuropathies – carpal tunnel syndrome, trigeminal neuralgia, facial nerve palsy.
  • Polyneuropathies – diabetic, toxic, and other types.
  • Multiple sclerosis – diagnosis, monitoring, long-term support.
  • Dizziness and coordination disorders.
  • Sleep disturbances – insomnia, daytime sleepiness, fragmented sleep.
  • Anxiety, depression, and stress-related conditions.

Dr. Agapova helps patients manage complex neurological symptoms like pain, numbness, weakness, poor sleep, and emotional distress. Her consultations focus on accurate diagnosis, clear explanation of findings, and tailored treatment plans.

If you’re struggling with chronic pain, migraines, nerve disorders, or sleep problems, Dr. Agapova offers professional guidance to restore your well-being.

CameraBook a video appointment
More times
5.0(37)
Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

CameraBook a video appointment
More times
5.0(12)
Doctor

Jonathan Marshall Ben Ami

Family medicine8 years of experience

Dr. Jonathan Marshall Ben Ami is a licensed family medicine doctor in Spain. He provides comprehensive care for adults and children, combining general medicine with emergency care expertise to address both acute and chronic health concerns.

Dr. Ben Ami offers expert diagnosis, treatment, and follow-up for:

  • Respiratory infections (cold, flu, bronchitis, pneumonia).
  • ENT conditions such as sinusitis, ear infections, and tonsillitis.
  • Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
  • Urinary tract infections and other common infections.
  • Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
  • Acute conditions requiring urgent medical attention.
  • Headaches, migraines, and minor injuries.
  • Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

CameraBook a video appointment
More times
5.0(4)
Doctor

Salome Akhvlediani

Pediatrics11 years of experience

Dr Salome Akhvlediani is a paediatrician providing online consultations for children of all ages. She supports families with preventive care, diagnosis, and long-term management of both acute and chronic conditions.

Her areas of focus include:

  • Fever, infections, cough, sore throat, and digestive issues.
  • Preventive care – vaccinations, regular check-ups, and health monitoring.
  • Allergies, asthma, and skin conditions.
  • Nutritional advice and healthy development support.
  • Sleep difficulties, fatigue, and behavioural concerns.
  • Ongoing care for chronic or complex health conditions.
  • Guidance for parents and follow-up after medical treatment.

Dr Akhvlediani combines professional care with a warm, attentive approach – helping children stay healthy and supporting parents at every stage of their child’s growth.

CameraBook a video appointment
More times
View all doctors

Get updates and exclusive offers

Be the first to know about new services, marketplace updates, and subscriber-only promos.

Subscribe
Follow us on social media
FacebookInstagram
Logo
Oladoctor
Find a doctor
Doctors by specialty
Services
Choose language
© 2025 Oladoctor. All rights reserved.
VisaMastercardStripe