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Bronho-vaxom

Bronho-vaxom

Ask a doctor about a prescription for Bronho-vaxom

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Bronho-vaxom

PATIENT INFORMATION LEAFLET: INFORMATION FOR THE USER

Broncho-Vaxom

7 mg, hard capsules

To be used in adults

Active substance: lyophilized bacterial lysate

Please read carefully the contents of this leaflet before taking the medicine, as it contains

important information for the patient.

  • This leaflet should be kept, as it may be necessary to read it again.
  • In case of any doubts, the doctor or pharmacist should be consulted.
  • This medicine has been prescribed specifically for one person. It should not be given to others. The medicine may harm another person, even if the symptoms of their disease are the same.
  • If the patient experiences any side effects, including any possible side effects not listed in this leaflet, the doctor or pharmacist should be informed. See section 4.

Table of contents of the leaflet

  • 1. What is Broncho-Vaxom and what is it used for
  • 2. Important information before taking Broncho-Vaxom
  • 3. How to take Broncho-Vaxom
  • 4. Possible side effects
  • 5. How to store Broncho-Vaxom
  • 6. Contents of the pack and other information

1. What is Broncho-Vaxom and what is it used for

Broncho-Vaxom is an immunostimulant medicine. It contains a lysate of bacteria that most commonly cause respiratory tract infections.
In humans, the medicine stimulates cellular and humoral immune mechanisms by activating macrophages, increasing the number of circulating T lymphocytes, and increasing the concentration of immunoglobulins secreted by the mucous membrane of the respiratory tract.
The indications for the use of Broncho-Vaxom are as follows:

  • prevention of recurrent respiratory tract infections (RTIs) in adults.

2. Important information before taking Broncho-Vaxom

When not to take Broncho-Vaxom

  • if the patient is allergic to the active substance or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Before starting to take Broncho-Vaxom, the doctor or pharmacist should be consulted.
In case of an allergic reaction to Broncho-Vaxom, treatment should be stopped immediately and the doctor informed.
It is not recommended to use Broncho-Vaxom to prevent pneumonia, as there are no clinical trial data confirming such an effect.
Use in the elderly
The elderly population was widely represented in clinical trials of Broncho-Vaxom. No safety concerns were identified.
Kidney function impairment
Data on the use of Broncho-Vaxom in patients with impaired kidney function are limited.
In preclinical toxicity studies, no signs of nephrotoxicity were observed in rats or dogs. Therefore, the use of Broncho-Vaxom in this patient group does not raise safety concerns.
Liver function impairment
There are no available data on the use of Broncho-Vaxom in patients with impaired liver function.
In preclinical toxicity studies, no signs of hepatotoxicity were observed in rats or dogs. Therefore, the use of Broncho-Vaxom in this patient group does not raise safety concerns.

Broncho-Vaxom and other medicines

The doctor or pharmacist should be informed about all medicines the patient is currently taking or has recently taken, as well as any medicines the patient plans to take.
No interactions have been identified between Broncho-Vaxom and other medicines.

Pregnancy, breastfeeding, and fertility

If the patient is pregnant or breastfeeding, thinks she may be pregnant, or plans to have a child, she should consult her doctor or pharmacist before taking this medicine.
Pregnancy
Only limited data are available on the use of Broncho-Vaxom in pregnant women.
Animal studies have not shown any direct or indirect harmful effects on reproduction.
As a precautionary measure, it is recommended to avoid the use of Broncho-Vaxom during pregnancy.
Breastfeeding
No studies have been conducted to assess the use of Broncho-Vaxom in breastfeeding women. As a precautionary measure, it is recommended to avoid the use of Broncho-Vaxom in breastfeeding women.

Driving and using machines

The medicine has no or negligible influence on the ability to drive and use machines.
Broncho-Vaxom contains sodium
This medicine contains less than 1 mmol of sodium (23 mg) per hard capsule, which means the medicine is considered "sodium-free".

3. How to take Broncho-Vaxom

This medicine should always be taken as directed by the doctor or pharmacist. In case of doubts, the doctor or pharmacist should be consulted.
Broncho-Vaxom is intended for oral use in adults.
The recommended dose is:
Prophylactic treatment cycle in case of recurrent respiratory tract infections:
One hard capsule (7 mg for adults) per day on an empty stomach, for 10 consecutive days per month for 3 consecutive months.
In case of an acute phase of respiratory tract infections, the medicinal product may be used in conjunction with appropriate treatment methods.
If necessary, the prophylactic treatment cycle can be repeated.
Method of administration
For oral use.
If the patient cannot swallow the capsule, it can be opened and its contents poured into a suitable amount of water, fruit juice, or milk.
The mixture dissolves under gentle stirring.
The mixture should be taken in its entirety within a few minutes and always stirred just before drinking.

Overdose of Broncho-Vaxom

The doctor should be contacted.

Missed dose of Broncho-Vaxom

A double dose should not be taken to make up for a missed capsule. The next dose should be taken at the usual time.

Stopping treatment with Broncho-Vaxom

Treatment should not be stopped without consulting the doctor.
In case of doubts related to the use of the medicine, the doctor or pharmacist should be consulted.

4. Possible side effects

Like all medicines, Broncho-Vaxom can cause side effects, although not everybody gets them.
The following side effects have been observed:

Common (may affect up to 1 in 10 people):

Headache, cough, diarrhea, abdominal pain, rash

Uncommon (may affect up to 1 in 100 people):

Nausea, vomiting, hives, fever, fatigue
Allergic reactions, including: rash with red spots on the skin, rash covering the whole body, redness (erythema), swelling, including swelling of the eyelids or face, fluid accumulation in the feet, ankles, or legs (peripheral edema), swelling, facial swelling, itching, including itching all over the body, shortness of breath

Frequency not known (frequency cannot be estimated from the available data):

Facial swelling, lips, tongue, throat, hands, and feet (angioedema)
In case of skin reactions and respiratory system disorders, gastrointestinal disorders, the use of Broncho-Vaxom should be stopped and medical advice sought.

Reporting side effects

If any side effects occur, including any possible side effects not listed in this leaflet, the doctor or pharmacist should be informed. Side effects can also be reported directly to the Department of Pharmacovigilance of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products:
Jerozolimskie Avenue 181 C
02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of the medicine.

5. How to store Broncho-Vaxom

Store in a place out of sight and reach of children.
Do not use this medicine after the expiry date stated on the blister and carton, in the section marked "Expiry date" (EXP). The expiry date refers to the last day of the month.
Store below 25°C.
Store in the original package to protect from moisture.
Medicines should not be disposed of via wastewater or household waste. The pharmacist should be asked how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Contents of the pack and other information

What Broncho-Vaxom contains

The active substance is OM-85 lyophilisate
40 mg
including lyophilized bacterial lysates:
Haemophilus influenzae, Streptococcus (Diplococcus)
pneumoniae Klebsiella pneumoniae ssp. pneumoniae and ssp.
ozaenae, Staphylococcus aureus, Streptococcus pyogenes and
sanguinis (viridans), Moraxella (Branhamella/Neisseria)
catarrhalis
7 mg
propyl gallate (E 310)
84 micrograms
sodium glutamate (E 621)
3.03 mg
mannitol
up to 40 mg
Other ingredients of the medicine arestarch (gelatinized), magnesium stearate, mannitol
Composition of the capsule shell:
gelatin, indigo carmine (E 132), titanium dioxide (E 171)

What Broncho-Vaxom looks like and contents of the pack

Broncho-Vaxom is in non-transparent capsules with a blue body and blue cap.
Pack of 10 hard capsules (1 blister of 10, in a carton)
Pack of 30 hard capsules (3 blisters of 10, in a carton)
Not all pack sizes may be marketed.

Marketing authorization holder and importer

Marketing authorization holder

OMEDICAMED Unipessoal Lda,
Avenida António Augusto de Aguiar nº 19 – 4º
1050-012 Lisboa
Portugal

Importer

FLAVINE PHARMA FRANCE
3 voie d’Allemagne,
13127 Vitrolles, France.
For more detailed information, please contact:
Sandoz Polska Sp. z o.o.
Domaniewska 50 C
02-672 Warsaw
Phone: 22 209 70 00, e-mail: [email protected]
Date of last revision of the leaflet:January 2023

Alternatives to Bronho-vaxom in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Bronho-vaxom in Ukraine

Dosage form: tablets, 14 or 28 tablets in a container
Prescription required
Dosage form: capsules, 3.5 mg
Dosage form: capsules, 7 mg, 10 capsules in a blister
Dosage form: capsules, 7 mg, 10 capsules in a blister
Manufacturer: OM Farma SA
Prescription required
Dosage form: capsules, 3.5 mg; 10 capsules in a blister
Manufacturer: OM Farma SA
Prescription required
Dosage form: tablets, 10 tablets in a blister
Prescription not required

Alternative to Bronho-vaxom in Spain

Dosage form: PULMONARY INHALATION, 800 ppm mol/mol
Active substance: nitric oxide
Prescription required
Dosage form: PULMONARY INHALATION, 450 ppm mol/mol
Active substance: nitric oxide
Prescription required
Dosage form: TABLET, 50 mg / 75 mg
Active substance: ivacaftor and tezacaftor
Prescription required
Dosage form: TABLET, 100 mg tezacaftor / 150 mg ivacaftor
Active substance: ivacaftor and tezacaftor
Prescription required
Dosage form: PULMONARY INHALATION, 800 ppm (V/V)
Active substance: nitric oxide
Prescription required
Dosage form: ORAL SOLUTION/SUSPENSION, 75 MG / 94 MG
Active substance: ivacaftor and lumacaftor
Prescription required

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