ALPICORT 2 mg + 0.05 Mg + 4 Mg/Ml Liquid

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About the medicine

How to use Alpicort E

Contents of the leaflet

  1. Package Leaflet: Information for the Patient
  2. Warning! Keep the Leaflet! Information on the Immediate Packaging in a Foreign Language.
  3. Alpicort E
    1. You should carefully read the contents of the leaflet before using the medicine, as it contains important information for the patient.
    2. Table of Contents of the Leaflet:
  4. What is Alpicort E and what is it used for
  5. Important information before using Alpicort E
    1. When not to use Alpicort E:
    2. Warnings and precautions
    3. Alpicort E and other medicines
    4. Pregnancy and breastfeeding
    5. Driving and using machines
    6. Alpicort E contains propylene glycol
  6. How to use Alpicort E
    1. Duration of use
    2. Using more than the recommended dose of Alpicort E
    3. Missing a dose of Alpicort E
    4. Stopping use of Alpicort E
  7. Possible side effects
    1. Important side effects or symptoms to look out for and measures to be taken if they occur:
    2. Other side effects
    3. Reporting side effects
  8. How to store Alpicort E
  9. Contents of the packaging and other information
    1. What Alpicort E contains
    2. What Alpicort E looks like and contents of the pack
    3. Marketing authorization holder in Bulgaria, the country of export:
    4. Manufacturer:
    5. Parallel importer:
    6. Repackaged by:
    7. Date of leaflet approval: 16.04.2025

Package Leaflet: Information for the Patient

Warning! Keep the Leaflet! Information on the Immediate Packaging in a Foreign Language.

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Alpicort E

(2 mg + 0.05 mg + 4 mg)/ml, liquid for the skin
Prednisolone + Estradiol + Salicylic Acid

You should carefully read the contents of the leaflet before using the medicine, as it contains important information for the patient.

  • You should keep this leaflet, so that you can read it again if you need to.
  • In case of any doubts, you should consult a doctor or pharmacist.
  • This medicine has been prescribed specifically for you. Do not pass it on to others. The medicine may harm another person, even if their symptoms are the same.
  • If the patient experiences any side effects, including any side effects not listed in this leaflet, they should inform their doctor or pharmacist. See section 4.

Table of Contents of the Leaflet:

  • 1. What is Alpicort E and what is it used for
  • 2. Important information before using Alpicort E
  • 3. How to use Alpicort E
  • 4. Possible side effects
  • 5. How to store Alpicort E
  • 6. Contents of the packaging and other information

1. What is Alpicort E and what is it used for

Alpicort E is a liquid for the skin, containing prednisolone, female sex hormones, and salicylic acid for use on the scalp.
Indications: in various forms of alopecia, especially androgen-dependent alopecia.

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2. Important information before using Alpicort E

When not to use Alpicort E:

  • if the patient is allergic to prednisolone, salicylic acid, estradiol benzoate, or any of the other ingredients of this medicine (listed in section 6),
  • in infants, children, and adolescents under 18 years of age,
  • in cases of estrogen-dependent tumors or suspected estrogen-dependent tumors,
  • in cases of unexplained bleeding from the reproductive organs,
  • on mucous membranes, in the mouth, or in the eyes, and on the genital area or internally,
  • in cases of chickenpox, certain skin diseases (tuberculosis, syphilis), and inflammatory reactions to vaccinations,
  • in cases of fungal or bacterial skin infections,
  • in cases of perioral dermatitis (skin irritation around the mouth with redness and bumps) and rosacea (redness of the face with possible inflammatory or purulent pimples),
  • in cases of wet or acute scalp diseases.

Warnings and precautions

Before starting to use Alpicort E, you should discuss it with your doctor or pharmacist.
Alpicort E may only be used externally on the scalp due to its isopropyl alcohol content.
When treating for more than 2-3 weeks, due to the estrogen content in the solution, special precautions should be taken:

  • in cases of endometriosis (endometrial tissue outside the uterus) or mastopathy (breast tissue changes),
  • in women who are already taking estrogen-containing preparations, treatment should only be carried out under close medical supervision.

Protect your eyes and mucous membranes from contact with the preparation.
If the patient experiences blurred vision or other vision disturbances, they should contact their doctor.

Alpicort E and other medicines

Alpicort E may enhance the effects of other topically applied active substances due to its composition.
You should tell your doctor or pharmacist about all medicines you are currently taking or have recently taken, as well as any medicines you plan to take.

Pregnancy and breastfeeding

Pregnancy
If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a baby, you should consult your doctor or pharmacist before using this medicine.
During pregnancy, Alpicort E should not be used due to its salicylic acid content, except when used on small areas (less than 5 cm²).
Alpicort E should not be used due to its estrogen content.
If you become pregnant during treatment, you should stop using Alpicort E immediately. However, previous studies have not shown any effect on subsequent fertility.
During long-term treatment with glucocorticoids - a component of Alpicort E - during pregnancy, growth disturbances and harm to the unborn child cannot be excluded.
Breastfeeding
Your doctor should consider that prednisolone passes into breast milk.
The doctor will carefully assess whether it is necessary to use Alpicort E during breastfeeding. If long-term treatment is necessary, you should stop breastfeeding.
During breastfeeding, estrogens may change the amount and composition of breast milk. Small amounts of estrogens or their metabolites may pass into breast milk and affect the child. Glucocorticoids also pass into breast milk. Therefore, you should not breastfeed during treatment with Alpicort E, or you should only start treatment after the breastfeeding period has ended.

Driving and using machines

Alpicort E does not affect the ability to drive or use machines.

Alpicort E contains propylene glycol

The medicine contains 50 mg of propylene glycol per 1 ml of solution (approximately equivalent to 180 mg of propylene glycol per single application). Propylene glycol may cause skin irritation.

3. How to use Alpicort E

This medicine should always be used exactly as your doctor has told you. If you are not sure, you should ask your doctor or pharmacist.
Alpicort E should always be used in accordance with the doctor's recommendations and the instructions in this leaflet. If you have any doubts, you should consult your doctor again.
Alpicort E is a solution for use on the skin.
If your doctor does not recommend otherwise, you should use Alpicort E once a day, preferably in the evening.
Once the inflammatory symptoms have improved, you can reduce the application to 2-3 times a week.
Each time you use the medicine, follow these steps:

  • Remove the cap from the applicator.
  • Turn the bottle with the applicator upside down over your head so that the opening at the top is facing downwards.
  • Apply the medicine by moving the applicator with the opening facing downwards over the affected areas.
  • After using Alpicort E, replace the cap on the applicator.
  • Then massage your scalp with your fingers for 2-3 minutes.

Duration of use

The duration of treatment for small areas should not exceed 2-3 weeks due to the presence of prednisolone in the solution. Clinical experience includes treatment periods of up to 6 months. No studies have been conducted on the duration of action after discontinuation of the medicine.

If you use more than the recommended dose, you should contact your doctor or pharmacist immediately.

Missing a dose of Alpicort E

You should not take a double dose to make up for a missed dose.
You should continue treatment by taking the next scheduled dose at the usual time.

Stopping use of Alpicort E

You should discuss further action with your doctor, as the effectiveness of the treatment may be compromised.
If you have any further doubts about using this medicine, you should consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, Alpicort E can cause side effects, although not everybody gets them.

Important side effects or symptoms to look out for and measures to be taken if they occur:

Rarely(may affect up to 1 in 1,000 people): skin hypersensitivity (allergic contact dermatitis).

Other side effects

Very rarely(may affect up to 1 in 10,000 people): as with the use of any corticosteroid preparations, long-term use may lead to skin changes (reduction of skin thickness, widening of small blood vessels, formation of striae, steroid acne, perioral dermatitis, excessive body hair growth).
Unknown(frequency cannot be estimated from the available data): blurred vision.
Additionally, short-term skin irritations (e.g., burning, redness) are possible.
During long-term use in high doses or on large areas, as well as in cases of misuse, systemic corticosteroid effects are possible.

Reporting side effects

If you experience any side effects, including any side effects not listed in this leaflet, you should inform your doctor or pharmacist. You can report side effects directly to the Department for Monitoring of Adverse Reactions to Medicinal Products, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181C, 02-222 Warsaw, Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309, website: https://smz.ezdrowie.gov.pl.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Alpicort E

The medicine should be kept out of the sight and reach of children.
Store in a temperature below 30°C. Store in the original packaging to protect from light.
Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the month stated.
Medicines should not be disposed of via wastewater or household waste.
You should ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the packaging and other information

What Alpicort E contains

  • The active substances are prednisolone, estradiol benzoate, and salicylic acid.
  • The excipients are isopropyl alcohol, propylene glycol, arginine, and purified water.

What Alpicort E looks like and contents of the pack

Alpicort E is a clear, colorless solution. The packaging contains a brown glass bottle with an applicator and a polypropylene closure, containing 100 ml of the medicine, and a leaflet.
For more detailed information, you should contact the marketing authorization holder or the parallel importer.

Marketing authorization holder in Bulgaria, the country of export:

Dr. August Wolff GmbH & Co. KG Arzneimittel
Sudbrackstrasse 56
33611 Bielefeld
Germany

Manufacturer:

Dr. August Wolff GmbH & Co. KG Arzneimittel
Sudbrackstrasse 56
33611 Bielefeld
Germany

Parallel importer:

InPharm Sp. z o.o.
ul. Strumykowa 28/11
03-138 Warsaw

Repackaged by:

InPharm Sp. z o.o. Services sp. k.
ul. Chełmżyńska 249
04-458 Warsaw
Marketing authorization number in Bulgaria, the country of export:20011278
Parallel import authorization number:281/15

Date of leaflet approval: 16.04.2025

[Information about the trademark]

  • Country of registration
  • Dosage form
    Liquid, (2 mg + 0.05 mg + 4 mg)/ml
  • ATC code
    D07XA02
  • Active substance
  • Prescription required
    Yes
  • Marketing authorisation holder (MAH)
    Dr. August Wolff GmbH & Co. KG Arzneimittel
  • Alternatives to Alpicort E
    Dosage form: Liquid, (2 mg + 0.05 mg + 4 mg)/ml
    Active substance: prednisolone
    Prescription required
    Dosage form: Liquid, (2 mg + 0.05 mg + 4 mg)/ml
    Active substance: prednisolone
    Prescription required
    Dosage form: Liquid, (2 mg + 0.05 mg + 4 mg)/ml
    Active substance: prednisolone
    Prescription required

Online doctors for Alpicort E

Discuss questions about Alpicort E, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(1)

Tomasz Grzelewski

DermatologyAllergology21 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€86
Doctor
5.0(4)

Lizaveta Trafimchuk Takhvaniuk

DermatologyFamily medicine10 years of experience

Dr. Lizaveta Trafimchuk Takhvaniuk graduated in Medicine and subsequently specialized in Dermatology and Venereology. She has more than 10 years of clinical experience and is licensed to practice in Spain, where she focuses on the comprehensive diagnosis and treatment of dermatological conditions.

Throughout her education and professional career, Dr. Trafimchuk has gained extensive experience in managing diseases of the skin, hair, and nails, as well as in the diagnosis, treatment, and prevention of sexually transmitted infections (STIs). Her clinical approach is based on evidence-based medicine, combined with personalized care tailored to each patient’s needs.

In her daily practice, she treats a wide range of dermatological conditions, including chronic inflammatory dermatoses such as acne, rosacea, atopic dermatitis, psoriasis, and eczema. She also has experience in treating pigmentation disorders, including melasma, post-inflammatory hyperpigmentation, and dyschromia.

She has developed a particular interest in trichology, treating various types of alopecia, chronic hair loss, and scalp disorders. In addition, she has experience in managing infectious dermatoses of fungal, viral, and bacterial origin, as well as in evaluating benign and suspicious skin lesions, with referral to specialized care when necessary.

With a strong interest in a comprehensive approach to skin health, she also treats scars, post-procedural skin changes, and conditions related to hormonal factors and aging, including those associated with pregnancy, menopause, and age-related skin changes.

Thanks to her experience and continuous professional development, Dr. Trafimchuk provides high-quality medical care that is professional, confidential, and aligned with modern dermatology standards.

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€72
Doctor
0.0(0)

Daria Litash

Dermatology2 years of experience

Dr. Daria Litash is an experienced physician specializing in general medicine, weight management, healthy weight loss, and overall wellness. Her approach combines thorough medical assessment with personalized recommendations to help patients improve their health and maintain an active, balanced lifestyle.

During every online consultation, she places particular emphasis on taking a detailed medical history and identifying the underlying causes of symptoms. When clinically appropriate, she recommends blood tests or additional diagnostic investigations to provide a more accurate assessment and create an individualized treatment plan.

Her main areas of expertise include:

  • Healthy weight management and weight loss
  • Overweight treatment and long-term weight maintenance
  • Hair loss assessment and management
  • Skin health evaluation
  • General medical consultations for adults
  • Preventive medicine and healthy lifestyle guidance

Dr. Litash also holds a qualification in Aesthetic Medicine, allowing her to approach skin and hair concerns from both a medical and preventive perspective, always following evidence-based principles and current clinical recommendations.

Her professional background includes several years of experience working in community pharmacy in Spain, providing her with extensive knowledge of medications, treatment options, and therapeutic alternatives available on the Spanish market, as well as experience in selecting international pharmaceutical products when clinically appropriate.

Her online consultations are designed to provide clear, personalized, and patient-centered medical care, helping individuals better understand their health, make informed treatment decisions, and achieve sustainable long-term wellbeing.

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€96

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Frequently Asked Questions

Is a prescription required for Alpicort E?

Alpicort E requires a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in Alpicort E?

The active ingredient in Alpicort E is prednisolone. This information helps identify medicines with the same composition but different brand names.

Who manufactures Alpicort E?

Alpicort E is manufactured by Dr. August Wolff GmbH & Co. KG Arzneimittel. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of Alpicort E online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Alpicort E is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy Alpicort E in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy Alpicort E in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to Alpicort E?

Other medicines with the same active substance (prednisolone) include Alpicort E, Alpicort E, Alpicort E. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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